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2건 · 최신순-
Building-block architecture of botulinum toxin complex: Conformational changes provide insights into the hemagglutination ability of the complex.
produces the botulinum neurotoxin (BoNT). Previously, we provided evidence for the "building-block" model of botulinum toxin complex (TC). In this model, a single BoNT is associated with a single nontoxic nonhemagglutinin (NTNHA), yielding …
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Conformational divergence in the HA-33/HA-17 trimer of serotype C and D botulinum toxin complex.
Clostridium botulinum produces a large toxin complex (L-TC) comprising botulinum neurotoxin associated with auxiliary nontoxic proteins. A complex of 33- and 17-kDa hemagglutinins (an HA-33/HA-17 trimer) enhances L-TC transport across the i…