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27건 · 최신순-
[Application of single-layer forearm flap in the repair of perforating defect of palate].
To evaluate the feasibility and clinical efficacy of a single-layer radial forearm free flap (RFFF) for through-and-through palatal defects. The single-layer forearm flap was used to repair 6 cases of perforating palatal defect due to oral …
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Anatomical Mapping of the Masseter for Safe Botulinum Toxin Injection: A Cadaveric Study.
[BACKGROUND] Botulinum toxin (BTX) is commonly used in masseter injections to enhance facial contour. However, the injection may harm the surrounding structure due to insufficient research on the anatomical structure of the masseter region.…
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Preexpanded Brachial Artery Perforator Propeller Flap: An Addition to the Armamentarium for Postburn Axillary Contracture Reconstruction.
[BACKGROUND] Postburn axillary contracture is a common complication that leads to functional impairment and unsatisfactory aesthetic outcomes. The authors present their experience with axillary contracture reconstruction using preexpanded b…
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Rectal neuroendocrine tumor during anorectal surgery: three case reports and a review of the literature.
[BACKGROUND] Rectal neuroendocrine tumors (NET) are thought to originate from the diffuse neuroendocrine system. The lack of apparent signs of illness and the patient's non-specific presentations often cause a delay in diagnosis, until in t…
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The Clinical Application and Significance of Contouring the Middle Cerebral Artery Under the Guidance of Three Dimensional Time-of-Flight Magnetic Resonance Angiography During the Surgical Resection of Insular Gliomas.
[OBJECTIVE] The clinical application of middle cerebral artery contouring, guided by the three-dimensional time-of-flight magnetic resonance angiography (3D-TOF MRA) during the surgical resection of insular glioma, was retrospectively analy…
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Machine learning approach to predict surgical site infection in head and neck squamous cell carcinoma patients after free flap reconstruction.
Head and neck squamous cell carcinoma (HNSCC) patients undergoing free flap reconstruction face a high risk of surgical site infection (SSI). Logistic regression (LR) models for SSI prediction are limited by linear assumptions, while machin…
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Ameliorative effects of HGF-overexpressed exosomes derived from ADMSCs on oxidative stress in hepatic fibrosis.
[BACKGROUND] Hepatic fibrosis, ultimately causing hepatic sclerosis, remains significant health concerns. Adipose-derived mesenchymal stem cell (ADMSC)-derived exosomes (Exo) exhibit amelioration of liver injury. Hepatocyte growth factor (H…
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Efficacy of injection therapies in reducing hemiplegic shoulder pain: a systematic review and meta-analysis.
[OBJECTIVE] This systematic review of randomized controlled trials (RCTs) with meta-analysis aimed to investigate the efficacy of injection therapies in reducing hemiplegic shoulder pain (HSP) in stroke survivors. [METHODS] PubMed, Embase …
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Integrated metabolomics and proteomics analysis in children with cerebral palsy exposed to botulinum toxin-A.
[BACKGROUND] We previously examined plasma metabolic changes before and after botulinum toxin-A injections of cerebral palsy (CP) children and showed that the glycine, serine and threonine metabolism may play a key role in neuritogenesis. T…
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Causes and therapeutic limitations of clinical alopecia and the advent of human pluripotent stem cell follicular transplantation.
Hair loss is a prevalent condition that affects many people worldwide and is often associated with self-neglect and anxiety. Hair transplantation is emerging as a viable therapeutic option for addressing several forms of hair loss that are …
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Case Report on Necrotizing Fasciitis after Liposuction and Abdominoplasty.
Liposuction and abdominoplasty are common cosmetic procedures, but they can lead to severe complications such as necrotizing fasciitis (NF), which is a life-threatening infection with rapid progression and significant mortality rates. NF ca…
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Untethered Microgrippers for Precision Medicine.
Microgrippers, a branch of micro/nanorobots, refer to motile miniaturized machines that are of a size in the range of several to hundreds of micrometers. Compared with tethered grippers or other microscopic diagnostic and surgical equipment…
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Localization of the Submandibular Glands Using High-Frequency Ultrasound.
[BACKGROUND] Injecting botulinum toxin (BTX) into the submandibular glands (SMGs) can treat drooling symptoms in neurological diseases and improve the aesthetics of SMG hypertrophy and ptotic SMGs. [OBJECTIVES] This study aimed to define t…
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Gut commensal metabolite rhamnose promotes macrophages phagocytosis by activating SLC12A4 and protects against sepsis in mice.
Sepsis progression is significantly associated with the disruption of gut eubiosis. However, the modulatory mechanisms of gut microbiota operating during sepsis are still unclear. Herein, we investigated how gut commensals impact sepsis dev…
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Clinical efficacy of flap transfer coverage in the treatment of vesicovaginal fistula.
[INTRODUCTION AND HYPOTHESIS] Vesicovaginal fistula (VVF) brings severe psychological, physiological, and social stress to patients, which seriously affects the quality of their sexual life. Traditional transvaginal repair surgery can cause…
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Therapeutic effect of exosomes derived from hepatocyte-growth-factor-overexpressing adipose mesenchymal stem cells on liver injury.
[UNLABELLED] Adipose mesenchymal stem cell-derived exosomes (ADMSC-Exo) are a new strategy for the treatment of liver injury. However, mesenchymal stem cells (MSCs) exert therapeutic effects mainly by secreting hepatocyte growth factor (HGF…
- A rare case of multiple eccrine hidrocystoma with severe hyperhidrosis successfully treated with botulinum toxin-A injection.
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Individualized High Double Eyelid Fold Correction in Secondary Blepharoplasty: A Free-Style Design.
[BACKGROUND] High crease correction is difficult to achieve in secondary blepharoplasty. Currently, patients tend to have more precise requirements for crease-lowering procedures, such as low in-fold or low out-fold creases. For the out-fol…
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Biohybrid Micro- and Nanorobots for Intelligent Drug Delivery.
Biohybrid micro- and nanorobots are integrated tiny machines from biological components and artificial components. They can possess the advantages of onboard actuation, sensing, control, and implementation of multiple medical tasks such as …
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Techniques and long-term outcomes of Y-shaped autologous dura mater wrap-clipping of blood blister-like aneurysms.
[BACKGROUND] The optimal surgical strategy for treating internal carotid artery (ICA) blood blister-like aneurysms (BBAs) has remained unclear. Wrap-clipping is one of the recommended treatments for BBAs, but the long-term clinical and angi…
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Clinical characteristics and management experience of schwannoma in extremities: Lessons learned from a 10-year retrospective study.
[INTRODUCTION] Schwannomas are the most common neoplastic lesions of the peripheral nerves when growing on the extremities, they usually have adverse effects on patients due to the exposed and functional nature of the region. [METHODS] In …
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Ultrasound-guided injection of botulinum toxin type A blocks cardiac sympathetic ganglion to improve cardiac remodeling in a large animal model of chronic myocardial infarction.
[BACKGROUND] Strategies to improve various cardiovascular diseases by blocking cardiac sympathetic ganglion have been increasingly available currently. Botulinum toxin type A (BTA), a typical neurotoxin, has been shown to block neural trans…
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Double Eyelid Shape Preference: A Large Sample Survey.
[BACKGROUND] Double eyelid blepharoplasty is a popular procedure among Asian population. Double eyelid shape is important to achieving high satisfaction rate. Currently, there lacks large sample survey and detailed analysis on preferred dou…
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A randomized controlled trial evaluating the hemodynamic impact of ultrasound-guided great auricular nerve block in middle ear microsurgery.
[BACKGROUND] The peri-operative effectiveness of ultrasound-guided great auricular nerve block (GANB) in patients, especially in adult patients undergoing middle ear microsurgery remains unclear. We hypothesized that ultrasound-guided GANB …
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miR-506 regulates cell proliferation and apoptosis by affecting RhoA/ROCK signaling pathway in hepatocellular carcinoma cells.
[BACKGROUND] Hepatocellular carcinoma (HCC), is the third leading cause of cancer-related death. MicroRNA-506 (miR-506) has been reported to exhibit abnormal expression in HCC; however, the role of miR-506 in HCC and the molecular mechanism…
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Emerging roles of RAC1 in treating lung cancer patients.
The Ras-related C3 botulinum toxin substrate 1 (RAC1), a member of the Rho family of small guanosine triphosphatases, is critical for many cellular activities, such as phagocytosis, adhesion, migration, motility, cell proliferation, and axo…
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A facelift for the general transcription factor TFIIA.
TFIIA was classified as a general transcription factor when it was first identified. Since then it has been debated to what extent it can actually be regarded as "general". The most notable feature of TFIIA is the proteolytical cleavage of …