보툴리눔독소 주사 Botulinum Toxin Injection

[INTRODUCTION] Facial aging results from intrinsic biologic decline and extrinsic environmental influences, producing progressive changes in skin structure, collagen integrity, and soft-tissue support. Botulinum neurotoxin type A (BoNTA) is…

The aim was to investigate the effects of botulinum toxin type A (BTX-A) treatment on sleep quality in patients diagnosed with probable sleep bruxism and awake bruxism. A prospective observational study was conducted on 40 female patients. …

Gastroparesis is a chronic gastric motility disorder marked by delayed gastric emptying in the absence of mechanical obstruction. For patients with symptoms refractory to medical and dietary therapy, Gastric Peroral Endoscopic Myotomy (G-PO…

[OBJECTIVES] Botulinum toxin A (BtxA) injection for AdLD is typically performed approxiamately every 3 months. DaxibotulinumtoxinA-lanm (Daxi) is a peptide-formulated neuromodulator with reported longer therapeutic duration. This study comp…

[BACKGROUND] Chronic anal fissures are a painful condition characterized by a tear in the anal mucosa. Botulinum toxin injection is a minimally invasive treatment option, but long-term effectiveness in recurrent or persistent cases remains …

Metabolic dysfunction-associated steatohepatitis (MASH), an inflammatory subtype of metabolic dysfunction-associated fatty liver disease (MAFLD), drives hepatic dysfunction and poses a significant health burden. Lipophagy dysfunction disrup…

[BACKGROUND] The first International Parkinson and Movement Disorder Society Evidence-Based Medicine (MDS-EBM) review for essential tremor (ET) was published in 2019; since then, the modified Grading of Recommendations, Assessment, Developm…

[BACKGROUND] Many popular botulinum neurotoxin treatments are off-label, yet no review has comprehensively captured their effects. This study provides a systematic review of neurotoxin's off-label aesthetic applications, focusing on muscle …

[PURPOSE] Autologous fat transfer is widely used in reconstructive and aesthetic surgery; however, its efficacy is often limited by suboptimal fat graft survival. Various pharmacological adjuncts have been proposed to enhance fat graft viab…

[BACKGROUND] Counterfeit Botulinum Toxin A (BoNT-A) poses a growing global threat, particularly in aesthetic medicine where regulatory oversight is minimal and underreporting is widespread. Traditional pharmacovigilance systems such as FAER…

[OBJECTIVE] Functional popliteal artery entrapment syndrome (fPAES) is characterized by exertional leg pain caused by hypertrophic musculature in young adults. If history, examination and imaging suggest fPAES, treatment is surgical includi…

Botulism is a rare but high-consequence foodborne intoxication in which early recognition and prompt reporting are essential for a timely public health response. We conducted a retrospective review of suspected botulism notifications report…

[BACKGROUND] Immunothrombosis entails a tight interplay between thrombotic and inflammatory pathways and plays a pathological role in ischemic stroke and venous thrombosis. mTOR (mechanistic target of rapamycin) is a canonical serine/threon…

[IMPORTANCE] Myofascial pelvic pain (MPP) is an under-treated etiology of pelvic pain, presenting with pelvic floor tender points and/or increased tension. While limited data support off-label use of pelvic floor botulinum toxin (BTA) injec…

[IMPORTANCE] Intradetrusor chemodenervation with onabotulinumtoxinA (BOTOX) injections, a common office-based procedure for overactive bladder (OAB), is associated with patient anxiety and discomfort. Aromatherapy and music have been shown …

[BACKGROUND] Most commercially available botulinum toxin A (BoNT-A) formulations are lyophilized or vacuum-dried powders requiring reconstitution. Recently a ready-to-use formulation (RTUaboBoNT-A) has been introduced. Although its efficacy…

[AIM OF THE STUDY] Evaluate and compare F‑wave and cutaneous silent period (CSP) parameters in caput‑pattern idiopathic cervical dystonia (CD) in the waning phase of botulinum toxin therapy vs. healthy controls to identify alterations in se…