히알루론산 Hyaluronic Acid

[BACKGROUND] An ileostomy is a commonly performed procedure in patients with various gastrointestinal conditions. A portion of small bowel (ileum) is brought through the anterior abdominal wall via a surgical opening called a stoma where fe…

Submental fullness, commonly referred to as a double chin, is a frequent aesthetic concern influenced by subcutaneous fat accumulation and underlying skeletal structure. High-intensity focused ultrasound (HIFU) and hyaluronic acid (HA) fill…

[BACKGROUND] Nasolabial folds (NLFs) are a hallmark of facial ageing, and precise correction requires detailed anatomical and vascular mapping. High-resolution ultrasound offers real-time visualisation of soft-tissue layers, filler distribu…

Knee osteoarthritis (KOA) is a chronic degenerative joint disease that lead to cartilage loss, inflammation, and disability. Intra-articular hyaluronic acid (HA) is widely used for its viscoelastic, anti-inflammatory, and chondroprotective …

Diagnosing late-onset complications after hyaluronic acid (HA) fillers can be challenging, particularly when clinical symptoms are mild. Although ultrasound (US) is widely regarded as the gold standard for evaluating facial fillers, it has …

Vascular occlusion is an uncommon but serious complication of hyaluronic acid filler injections. If not recognized and managed early, it can lead to ischemia and even skin necrosis. Timely diagnosis and intervention are therefore crucial to…

[BACKGROUND] This post-marketing study evaluated the clinical performance and safety of Belotero Volume (CPM-V) and Belotero Volume Lidocaine (CPM-V+) for chin augmentation in a real-world setting. [METHODS] This prospective, open-label, r…

[BACKGROUND] Facial Overfilled Syndrome (FOS) is an increasingly prevalent iatrogenic complication resulting from the excessive or inappropriate use of dermal fillers. Clinically significant for causing facial distortion and unnatural dynam…

Nonsurgical rhinoplasty (NSR) is a minimally invasive alternative to surgical rhinoplasty that uses dermal fillers to enhance nasal aesthetics. When performed by trained injectors, NSR offers rapid correction with relatively low downtime. T…

[BACKGROUND] Nonsurgical rhinoplasty (NSR) may achieve a satisfactory aesthetic result. However, if NSR falls short of patient goals, patients may then elect to undergo surgical rhinoplasty. This latter cohort of patients has not been well …

[BACKGROUND] Filler-induced vascular occlusion remains a rare but serious complication in aesthetic medicine, particularly in the lips, where collateral circulation is limited. Polynucleotide (DOT-PN) is a polynucleotide-based medical devic…

Temporomandibular disorder (TMD) is a condition affecting a growing population of people worldwide. It is an etiologically, diagnostically and therapeutically challenging condition. The aim of this article was to present difficult and impor…

The rising number of Hyaluronic acid (HA) filler applications has led to an increase in the incidence of complications, which can range from undesired aesthetic outcomes to severe vascular occlusion events. Hyaluronidase (Hyal) hydrolyzes H…

In this review we present a comprehensive overview of the published literature related to the use of Hybrid Cooperative Complexes (HCCs) of low- and high-molecular-weight hyaluronic acid in aesthetic medicine. HCCs have been developed to ov…

[BACKGROUND] Hyaluronic acid (HA) filler injections are widely known to be safe; however, they cause rare and severe complications such as visual loss. No standardized treatment protocol has been established because of the rarity and hetero…

Despite treatments such as pentosan polysulfate, hyaluronic acid, botulinum toxin A, and platelet-rich plasma, many interstitial cystitis/bladder pain syndrome (IC/BPS) patients experience persistent symptoms. Urinary extracellular vesicles…

[BACKGROUND] Hyaluronic acid (HA) filler-induced vascular occlusion is a serious complication in aesthetic medicine, yet the microvascular behavior of HA gels under physiologically relevant flow conditions remains poorly characterized. [OB…

[OBJECTIVE] To evaluate whether the combination of exercise and intra-articular injection (IAI) effectively improves pain, function, and quality of life in patients with knee osteoarthritis (OA) compared to any control group in the short, m…

Aging lips often appear thin, inverted, and poorly defined due to disproportionate atrophy of deep labial fat and mucosa with relative preservation or increase of superficial fat. Traditional augmentation focused on superficial volumization…