Vasoconstrictors in facial plastic surgery.
Abstract
The effectiveness of local anesthetics is improved by the addition of a vasoconstrictor with an increased duration of action and the ability to decrease both systemic toxic reactions and local bleeding. Epinephrine, the standard drug for vasoconstriction, has some limitations due to potential cardiac and local toxic effects. Using an animal model, we compared the effects of various concentrations of epinephrine and two other vasoconstrictors, phenylephrine hydrochloride and felypressin, on local blood flow. We also examined the local effects of bupivacaine hydrochloride and ropivacaine hydrochloride, a new local anesthetic. We found that felypressin was as effective a vasoconstrictor as epinephrine, with fewer potential toxic reactions. Phenylephrine (Neo-Synephrine), on the other hand, was less effective, with a shorter duration of action. As expected, bupivacaine produced vasodilation, while ropivacaine was found to have vasoconstrictive properties.
추출된 의학 개체 (NER)
| 유형 | 영어 표현 | 한국어 / 풀이 | UMLS CUI | 출처 | 등장 |
|---|---|---|---|---|---|
| 약물 | epinephrine
|
에피네프린 | dict | 3 | |
| 해부 | blood
|
scispacy | 1 | ||
| 합병증 | facial plastic
|
scispacy | 1 | ||
| 약물 | Vasoconstrictors
|
C0042397
Vasoconstrictor Agents
|
scispacy | 1 | |
| 약물 | phenylephrine hydrochloride
|
C0031470
phenylephrine hydrochloride
|
scispacy | 1 | |
| 약물 | felypressin
|
C0015777
felypressin
|
scispacy | 1 | |
| 약물 | bupivacaine hydrochloride
|
C0887621
bupivacaine hydrochloride
|
scispacy | 1 | |
| 약물 | ropivacaine hydrochloride
|
C0771826
ropivacaine hydrochloride
|
scispacy | 1 | |
| 약물 | Phenylephrine
|
C0031469
phenylephrine
|
scispacy | 1 | |
| 약물 | Neo-Synephrine
|
C0702190
Neo-Synephrine
|
scispacy | 1 | |
| 약물 | bupivacaine
|
C0006400
bupivacaine
|
scispacy | 1 | |
| 약물 | ropivacaine
|
C0073571
ropivacaine
|
scispacy | 1 | |
| 질환 | systemic toxic reactions
|
scispacy | 1 | ||
| 질환 | cardiac
|
scispacy | 1 | ||
| 기타 | vasoconstrictors
|
scispacy | 1 |
MeSH Terms
Amides; Anesthetics, Local; Animals; Bupivacaine; Dermatologic Surgical Procedures; Epinephrine; Face; Felypressin; Lidocaine; Phenylephrine; Regional Blood Flow; Ropivacaine; Skin; Surgery, Plastic; Swine; Ultrasonics; Vasoconstriction; Vasoconstrictor Agents
🔗 함께 등장하는 도메인
이 논문이 속한 카테고리와 같은 논문에서 자주 함께 다뤄지는 카테고리들
관련 논문
- Fat harvesting protocol for enhanced stem cell viability - pilot study.
- Optimizing Intraoperative Hemostasis in Hair Transplantation: A Follicle-Based Tumescent Infiltration Approach.
- Evaluating the Time of Maximal Vasoconstrictive Effect of Epinephrine in Facelift Surgery.
- The Impact of Local Tranexamic Acid Infiltration on Periorbital Ecchymosis and Edema in Rhinoplasty: A Triple-Blinded Randomized Controlled Trial.
- Recurrent Epistaxis Immediate Following Upper Blepharoplasty: Treatment with Tranexamic Acid.