Capsular contracture: a prospective study of the effect of local antibacterial agents.
Abstract
In a prospective, random, double-blind, and concurrently controlled clinical study of 124 patients having augmentation mammaplasty, using multiple independent subjective judges as well as objective compressibility measurements, the use of a variety of local antibacterials in or around inflatable retromammary prosthetic implants reduced the early postoperative onset of class III to IV capsular contracture by sevenfold (85 percent) and the final incidence by more than half (50 percent) (p less than 0.01). We believe this study provides the most unequivocal evidence to date that the cause of capsular contracture in retromammary augmentation is periprosthetic bacterial contamination. Irrigation with a 5 percent povidone-iodine (50 percent Betadine) solution was as effective as other techniques and is currently our procedure of choice.
추출된 의학 개체 (NER)
| 유형 | 영어 표현 | 한국어 / 풀이 | UMLS CUI | 출처 | 등장 |
|---|---|---|---|---|---|
| 합병증 | capsular contracture
|
피막구축 | dict | 3 | |
| 시술 | mammaplasty
|
유방성형술 | dict | 1 | |
| 해부 | retromammary
|
scispacy | 1 | ||
| 약물 | povidone-iodine
|
C0032857
povidone-iodine
|
scispacy | 1 | |
| 질환 | contracture
|
C0009917
Contracture
|
scispacy | 1 | |
| 기타 | Capsular
|
scispacy | 1 | ||
| 기타 | patients
|
scispacy | 1 | ||
| 기타 | class III to IV capsular
|
scispacy | 1 |
MeSH Terms
Administration, Topical; Anti-Bacterial Agents; Breast; Cephalothin; Clinical Trials as Topic; Double-Blind Method; Equipment Contamination; Equipment Failure; Female; Humans; Postoperative Complications; Povidone-Iodine; Prostheses and Implants; Prosthesis Failure; Random Allocation; Surgery, Plastic; Therapeutic Irrigation
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