Autoimmune, atopic, and mental health comorbid conditions associated with alopecia areata in the United States.
단면연구
4/5 보강
TL;DR
A high prevalence of comorbid conditions among individuals with AA presenting to academic medical centers in Boston found was different from that seen in a comparison psoriasis and psoriatic arthritis group.
PICO 자동 추출 (휴리스틱, conf 2/4)
유사 논문P · Population 대상 환자/모집단
350 patients and manually reviewed their medical records to train and validate a novel artificial intelligence program.
I · Intervention 중재 / 시술
추출되지 않음
C · Comparison 대조 / 비교
추출되지 않음
O · Outcome 결과 / 결론
We found a high prevalence of comorbid conditions among individuals with AA presenting to academic medical centers in Boston.
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· 인용됨 66
📑 인용한 논문 (6) ▾
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- Dermatologists' Perspectives and Real-World Assessment of Alopecia Areata Severity in Adul… Dermatology and therapy · 2026
- Ophthalmologic Comorbidities in Alopecia Areata. Journal of clinical medicine · 2025
- Alopecia Areata: Pathogenesis, Diagnosis, and Therapies. MedComm · 2025
- Causal Link of Distinct Mental Disorders with Androgenetic Alopecia and Alopecia Areata: A… Clinical, cosmetic and investigational dermatology · 2025
- Global Burden of Alopecia Areata and Associated Diseases: A Trend Analysis From 1990 to 20… Journal of cosmetic dermatology · 2025
🇰🇷 한글 요약 🌐 Abstract
【연구 목적】
미국 보스턴 3차 의료기관에서 11년간 진료받은 원형탈모(alopecia areata, AA) 환자에서 동반질환의 유병률을 평가하기 위함.
【방법】
2000~2011년 Partners 의료시스템에서 ICD-9 코드 704.01로 확인된 AA 환자 3,568명을 대상으로 후향적 단면연구를 수행하였으며, 자연어 처리(NLP) 기반 AI 알고리즘으로 자유 텍스트 의무기록을 분석하여 진단을 확정(검증 정확도 93.9%)함.
【주요 결과】
자가면역질환(갑상선질환 14.6%, 당뇨병 11.1%, 전신홍반루푸스 4.3%, 류마티스관절염 3.9%, 건선/건선관절염 6.3%, 염증성장질환 2.0%), 아토피질환(알레르기비염·천식·습진 38.2%, 접촉피부염 및 기타 습진 35.9%), 정신건강질환(우울 또는 불안 25.5%)의 유병률이 높았으며, 고지혈증(24.5%)·고혈압(21.9%)·위식도역류질환(17.3%)도 흔하게 동반됨.
【임상적 시사점 (성형외과 의사 관점)】
모발이식(hair transplantation)이나 두피 관련 시술 상담 시 단순 안드로겐성 탈모와 감별이 필요하며, AA 환자는 자가면역·아토피·정신건강 동반질환 선별이 권장됨. 특히 우울·불안 동반율이 25.5%로 높아 미용 시술 전 심리상태 평가와 비현실적 기대 관리가 중요하고, 활동성 AA 병변에서는 이식 시 Koebner 현상 위험이 있어 시술 시기 결정에 주의가 필요함.
[OBJECTIVE] To evaluate the prevalence of comorbid conditions among patients with alopecia areata (AA) seen at tertiary care hospitals in Boston, Massachusetts, during an 11-year period.
[DESIGN] Retrospective cross-sectional study.
[SETTING] Tertiary care hospitals in Boston, including Brigham and Women's Hospital and Massachusetts General Hospital.
[PARTICIPANTS] We identified 3568 individuals with AA seen in the Partners health care system in Boston between January 1, 2000, and January 1, 2011. We performed comprehensive searches of the Research Patient Data Repository using International Classification of Diseases, Ninth Revision code 704.01. We randomly selected 350 patients and manually reviewed their medical records to train and validate a novel artificial intelligence program. This program then used natural language processing to review free-text medical records and confirm a diagnosis of AA. To confirm the algorithm, we manually reviewed a subset of records and found 93.9% validity.
[MAIN OUTCOMES AND MEASURES] The prevalence of comorbid conditions was assessed.
[RESULTS] Common comorbid conditions included autoimmune diagnoses (thyroid disease in 14.6%, diabetes mellitus in 11.1%, inflammatory bowel disease in (2.0%) [corrected], systemic lupus erythematosus in 4.3%, rheumatoid arthritis in 3.9%, and psoriasis and psoriatic arthritis in (6.3%) [corrected], atopy (allergic rhinitis, asthma, and/or eczema in 38.2% and contact dermatitis and other eczema in 35.9%), and mental health problems (depression or anxiety in 25.5%). We also found high prevalences of hyperlipidemia (24.5%), hypertension (21.9%), and gastroesophageal reflux disease (17.3%). This profile was different from that seen in a comparison psoriasis and psoriatic arthritis group.
[CONCLUSIONS AND RELEVANCE] We found a high prevalence of comorbid conditions among individuals with AA presenting to academic medical centers in Boston. Physicians caring for patients with AA should consider screening for comorbid conditions.
[DESIGN] Retrospective cross-sectional study.
[SETTING] Tertiary care hospitals in Boston, including Brigham and Women's Hospital and Massachusetts General Hospital.
[PARTICIPANTS] We identified 3568 individuals with AA seen in the Partners health care system in Boston between January 1, 2000, and January 1, 2011. We performed comprehensive searches of the Research Patient Data Repository using International Classification of Diseases, Ninth Revision code 704.01. We randomly selected 350 patients and manually reviewed their medical records to train and validate a novel artificial intelligence program. This program then used natural language processing to review free-text medical records and confirm a diagnosis of AA. To confirm the algorithm, we manually reviewed a subset of records and found 93.9% validity.
[MAIN OUTCOMES AND MEASURES] The prevalence of comorbid conditions was assessed.
[RESULTS] Common comorbid conditions included autoimmune diagnoses (thyroid disease in 14.6%, diabetes mellitus in 11.1%, inflammatory bowel disease in (2.0%) [corrected], systemic lupus erythematosus in 4.3%, rheumatoid arthritis in 3.9%, and psoriasis and psoriatic arthritis in (6.3%) [corrected], atopy (allergic rhinitis, asthma, and/or eczema in 38.2% and contact dermatitis and other eczema in 35.9%), and mental health problems (depression or anxiety in 25.5%). We also found high prevalences of hyperlipidemia (24.5%), hypertension (21.9%), and gastroesophageal reflux disease (17.3%). This profile was different from that seen in a comparison psoriasis and psoriatic arthritis group.
[CONCLUSIONS AND RELEVANCE] We found a high prevalence of comorbid conditions among individuals with AA presenting to academic medical centers in Boston. Physicians caring for patients with AA should consider screening for comorbid conditions.
- 연구 설계 cross-sectional
【연구 목적】 미국 보스턴 3차 의료기관에서 11년간 진료받은 원형탈모(alopecia areata, AA) 환자에서 동반질환의 유병률을 평가하기 위함.
APA 7
Huang, K. P., Mullangi, S., Guo, Y., & Qureshi, A. A. (2013). Autoimmune, atopic, and mental health comorbid conditions associated with alopecia areata in the united states.. JAMA dermatology, 149(7), 789-94. https://doi.org/10.1001/jamadermatol.2013.3049
Vancouver
Huang KP, Mullangi S, Guo Y, Qureshi AA. Autoimmune, atopic, and mental health comorbid conditions associated with alopecia areata in the United States. JAMA dermatology. 2013;149(7):789-94. doi:10.1001/jamadermatol.2013.3049
AMA 11
Huang KP, Mullangi S, Guo Y, Qureshi AA. Autoimmune, atopic, and mental health comorbid conditions associated with alopecia areata in the United States. JAMA dermatology. 2013;149(7):789-94. doi:10.1001/jamadermatol.2013.3049
Chicago
Huang, K. P., Mullangi, S., Guo, Y., and Qureshi, A. A.. 2013. "Autoimmune, atopic, and mental health comorbid conditions associated with alopecia areata in the United States." JAMA dermatology 149 (7): 789-94. https://doi.org/10.1001/jamadermatol.2013.3049
MLA 9
Huang, K. P., et al. "Autoimmune, atopic, and mental health comorbid conditions associated with alopecia areata in the United States." JAMA dermatology, vol. 149, no. 7, 2013, pp. 789-94. doi:10.1001/jamadermatol.2013.3049.
PMID
23700152 ↗
🏷️ 키워드 / MeSH 📖 같은 키워드 OA만
- Adult
- Aged
- 80 and over
- Alopecia Areata
- Anxiety
- Asthma
- Autoimmune Diseases
- Boston
- Comorbidity
- Depression
- Dermatitis
- Contact
- Diabetes Mellitus
- Eczema
- Female
- Gastroesophageal Reflux
- Humans
- Hyperlipidemias
- Hypertension
- Inflammatory Bowel Diseases
- Male
- Middle Aged
- Prevalence
- Retrospective Studies
… 외 3개
인용 관계
그래프 OA 노드: 7/8 (88%)
· 참조 0편 · 후속 7편
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