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Comorbidity profiles among patients with alopecia areata: the importance of onset age, a nationwide population-based study.

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Journal of the American Academy of Dermatology 📖 저널 OA 27.5% 2021: 51/103 OA 2022: 38/93 OA 2023: 34/109 OA 2024: 41/104 OA 2025: 38/165 OA 2026: 24/195 OA 2021~2026 2011 Vol.65(5) p. 949-56 피인용 67회 cited 264 RCR 6.25 Hair Growth and Disorders
TL;DR Different associated diseases in each onset age group of AA can allow clinician to efficiently investigate specific comorbidities and clarify the role of atopic and autoimmune diseases in AA, thereby better understanding its pathogenesis.
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PubMed DOI OpenAlex Semantic 마지막 보강 2026-05-09

PICO 자동 추출 (휴리스틱, conf 2/4)

유사 논문
P · Population 대상 환자/모집단
4334 patients with AA were identified from the National Health Insurance Database in Taiwan from 1996 to 2008.
I · Intervention 중재 / 시술
추출되지 않음
C · Comparison 대조 / 비교
추출되지 않음
O · Outcome 결과 / 결론
[CONCLUSIONS] AA is related to various atopic and autoimmune diseases. Different associated diseases in each onset age group of AA can allow clinician to efficiently investigate specific comorbidities.
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📑 인용한 논문 (6) ▾
연도별 인용 (2012–2026) · 합계 259
OpenAlex 토픽 · Hair Growth and Disorders melanin and skin pigmentation Dermatology and Skin Diseases

Chu SY, Chen YJ, Tseng WC, Lin MW, Chen TJ, Hwang CY

PubMed ↗ DOI ↗ BibTeX ↓ RIS ↓

Abstract

[BACKGROUND] Alopecia areata (AA) is considered an autoimmune disease with undetermined pathogenesis. Age at onset predicts distinct outcomes. A nationwide study of the relationship of AA with associated diseases stratified by onset age has rarely been reported.

[OBJECTIVE] We sought to clarify the role of atopic and autoimmune diseases in AA, thereby better understanding its pathogenesis.

[METHODS] A total of 4334 patients with AA were identified from the National Health Insurance Database in Taiwan from 1996 to 2008. A national representative cohort of 784,158 persons served as control subjects.

[RESULTS] Among patients with AA, there were significant associations with vitiligo, lupus erythematosus, psoriasis, atopic dermatitis, autoimmune thyroid disease, and allergic rhinitis. Different ages at onset resulted in disparate comorbidities. Increased risk of atopic dermatitis (odds ratio [OR] 3.82, 95% confidence interval 2.67-5.45) and lupus erythematosus (OR 9.76, 95% confidence interval 3.05-31.21) were found in childhood AA younger than 10 years. Additional diseases including psoriasis (OR 2.43) and rheumatoid arthritis (OR 2.57) appeared at onset age 11 to 20 years. Most atopic and autoimmune diseases were observed at onset ages of 21 to 60 years. With onset age older than 60 years, thyroid disease (OR 2.52) was highly related to AA. Moreover, patients with AA had higher risk for more coexisting diseases than control subjects.

[LIMITATIONS] We could not differentiate hypothyroidism from hyperthyroidism.

[CONCLUSIONS] AA is related to various atopic and autoimmune diseases. Different associated diseases in each onset age group of AA can allow clinician to efficiently investigate specific comorbidities.
📝 환자 설명용 한 줄

Different associated diseases in each onset age group of AA can allow clinician to efficiently investigate specific comorbidities and clarify the role of atopic and autoimmune diseases in AA, thereby

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↓ .bib ↓ .ris
APA 7 Chu, S. Y., Chen, Y. J., Tseng, W. C., Lin, M. W., Chen, T. J., Hwang, C. Y., Chen, C. C., Lee, D. D., Chang, Y. T., Wang, W. J., & Liu, H. N. (2011). Comorbidity profiles among patients with alopecia areata: The importance of onset age, a nationwide population-based study.. Journal of the American Academy of Dermatology, 65(5), 949-56. https://doi.org/10.1016/j.jaad.2010.08.032
Vancouver Chu SY, Chen YJ, Tseng WC, Lin MW, Chen TJ, Hwang CY, et al. Comorbidity profiles among patients with alopecia areata: the importance of onset age, a nationwide population-based study. Jour. Amer. Acad. Derm.. 2011;65(5):949-56. doi:10.1016/j.jaad.2010.08.032
AMA 11 Chu SY, Chen YJ, Tseng WC, Lin MW, Chen TJ, Hwang CY, et al. Comorbidity profiles among patients with alopecia areata: the importance of onset age, a nationwide population-based study. Jour. Amer. Acad. Derm.. 2011;65(5):949-56. doi:10.1016/j.jaad.2010.08.032
Chicago Chu, S. Y., Chen, Y. J., Tseng, W. C., Lin, M. W., Chen, T. J., Hwang, C. Y., Chen, C. C., Lee, D. D., Chang, Y. T., Wang, W. J., and .... 2011. "Comorbidity profiles among patients with alopecia areata: the importance of onset age, a nationwide population-based study." Journal of the American Academy of Dermatology 65 (5): 949-56. https://doi.org/10.1016/j.jaad.2010.08.032
MLA 9 Chu, S. Y., et al. "Comorbidity profiles among patients with alopecia areata: the importance of onset age, a nationwide population-based study." Journal of the American Academy of Dermatology, vol. 65, no. 5, 2011, pp. 949-56. doi:10.1016/j.jaad.2010.08.032.
PMID 21616562 ↗
DOI 10.1016/j.jaad.2010.08.032

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그래프 OA 노드: 6/8 (75%) · 참조 0편 · 후속 6편

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