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Alopecia areata update: part I. Clinical picture, histopathology, and pathogenesis.

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Journal of the American Academy of Dermatology 📖 저널 OA 27.9% 2021: 51/103 OA 2022: 38/93 OA 2023: 34/109 OA 2024: 41/104 OA 2025: 43/165 OA 2026: 24/195 OA 2021~2026 2010 Vol.62(2) p. 177-88, quiz 189-90 피인용 114회 cited 728 RCR 12.64 Hair Growth and Disorders
TL;DR Part one of this two-part series on AA describes the clinical presentation and the associated histopathologic picture and proposes a hypothesis for AA development based on the most recent knowledge of disease pathogenesis.
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PubMed DOI OpenAlex Semantic 마지막 보강 2026-05-09
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OpenAlex 토픽 · Hair Growth and Disorders Skin and Cellular Biology Research Acne and Rosacea Treatments and Effects

Alkhalifah A, Alsantali A, Wang E, McElwee KJ, Shapiro J

Abstract

[UNLABELLED] Alopecia areata (AA) is an autoimmune disease that presents as nonscarring hair loss, although the exact pathogenesis of the disease remains to be clarified. Disease prevalence rates from 0.1% to 0.2% have been estimated for the United States. AA can affect any hair-bearing area. It often presents as well demarcated patches of nonscarring alopecia on skin of overtly normal appearance. Recently, newer clinical variants have been described. The presence of AA is associated with a higher frequency of other autoimmune diseases. Controversially, there may also be increased psychiatric morbidity in patients with AA. Although some AA features are known poor prognostic signs, the course of the disease is unpredictable and the response to treatment can be variable. Part one of this two-part series on AA describes the clinical presentation and the associated histopathologic picture. It also proposes a hypothesis for AA development based on the most recent knowledge of disease pathogenesis.

[LEARNING OBJECTIVES] After completing this learning activity, participants should be familiar with the most recent advances in AA pathogenesis, recognize the rare and recently described variants of AA, and be able to distinguish between different histopathologic stages of AA.
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Part one of this two-part series on AA describes the clinical presentation and the associated histopathologic picture and proposes a hypothesis for AA development based on the most recent knowledge of

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APA 7 Alkhalifah, A., Alsantali, A., Wang, E., McElwee, K. J., & Shapiro, J. (2010). Alopecia areata update: Part i. Clinical picture, histopathology, and pathogenesis.. Journal of the American Academy of Dermatology, 62(2), 177-88, quiz 189-90. https://doi.org/10.1016/j.jaad.2009.10.032
Vancouver Alkhalifah A, Alsantali A, Wang E, McElwee KJ, Shapiro J. Alopecia areata update: part I. Clinical picture, histopathology, and pathogenesis. Jour. Amer. Acad. Derm.. 2010;62(2):177-88, quiz 189-90. doi:10.1016/j.jaad.2009.10.032
AMA 11 Alkhalifah A, Alsantali A, Wang E, McElwee KJ, Shapiro J. Alopecia areata update: part I. Clinical picture, histopathology, and pathogenesis. Jour. Amer. Acad. Derm.. 2010;62(2):177-88, quiz 189-90. doi:10.1016/j.jaad.2009.10.032
Chicago Alkhalifah, A., Alsantali, A., Wang, E., McElwee, K. J., and Shapiro, J.. 2010. "Alopecia areata update: part I. Clinical picture, histopathology, and pathogenesis." Journal of the American Academy of Dermatology 62 (2): 177-88, quiz 189-90. https://doi.org/10.1016/j.jaad.2009.10.032
MLA 9 Alkhalifah, A., et al. "Alopecia areata update: part I. Clinical picture, histopathology, and pathogenesis." Journal of the American Academy of Dermatology, vol. 62, no. 2, 2010, pp. 177-88, quiz 189-90. doi:10.1016/j.jaad.2009.10.032.
PMID 20115945 ↗

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