Male androgenetic alopecia.
4/5 보강
TL;DR
Androgenetic alopecia is a progressive condition and although the current available treatments are effective in arresting the progression of the disease, they allow only partial regrowth of hair at its best.
📑 코퍼스 인용 관계
· 인용됨 42
📑 인용한 논문 (6) ▾
- Beyond the Follicle: A Narrative Review on How Systemic Diseases and Drugs Affect Alopecia… Pharmaceutical medicine · 2026
- Efficacy and Safety of Low-Dose (0.2 mg) Dutasteride for Male Androgenic Alopecia: A Multi… Annals of dermatology · 2025
- Male and female pattern hair loss. Australian prescriber · 2025
- Nanocrystal Structure of Minoxidil: A Safe Stimulator for Hair Growth Factor for C57BL/6 M… Current medicinal chemistry · 2025
- Modulating immune responses in alopecia: therapeutic insights and potential targets of ant… BMC immunology · 2025
- Adenosine as an Active Ingredient in Topical Preparations Against Hair Loss: A Systematic … Biomolecules · 2025
연도별 인용 (2012–2026) · 합계 155
OpenAlex 토픽 ·
Hair Growth and Disorders
Sexual Differentiation and Disorders
Acne and Rosacea Treatments and Effects
Abstract 🌐 Abstract
[IMPORTANCE OF THE FIELD] Androgenetic alopecia affects up to 80% of males by the age of 80. The synonym 'male-pattern hair loss' highlights the fact that hair loss occurs in a defined and reproducible pattern. Hair loss results in reduced self esteem, loss of confidence and anxiety in affected men. An effective treatment for hair baldness would be desirable.
[AREAS COVERED IN THIS REVIEW] In androgenetic alopecia, hair follicles undergo progressive miniaturization. Genetic factors and androgens play a major role in the pathogenesis of the disease. Polymorphism of the androgen receptor gene was first identified in association with androgenetic alopecia. Identification of new susceptibility genes on chromosomes 3q26 and 20p11 suggest that non-androgen-dependent pathways also are involved.
[WHAT THE READER WILL GAIN] Topical monoxidil and oral finasteride are commonly in use and have FDA approval for the treatment of male androgenetic alopecia; dutasteride, a type I and II 5-alpha-reductase inhibitor, is on hold in Phase III trials. A combination of medical treatment and hair transplant surgery has shown superior efficacy.
[TAKE-HOME MESSAGE] Androgenetic alopecia is a progressive condition and although the current available treatments are effective in arresting the progression of the disease, they allow only partial regrowth of hair at its best. Early treatment achieves the best desirable outcome.
[AREAS COVERED IN THIS REVIEW] In androgenetic alopecia, hair follicles undergo progressive miniaturization. Genetic factors and androgens play a major role in the pathogenesis of the disease. Polymorphism of the androgen receptor gene was first identified in association with androgenetic alopecia. Identification of new susceptibility genes on chromosomes 3q26 and 20p11 suggest that non-androgen-dependent pathways also are involved.
[WHAT THE READER WILL GAIN] Topical monoxidil and oral finasteride are commonly in use and have FDA approval for the treatment of male androgenetic alopecia; dutasteride, a type I and II 5-alpha-reductase inhibitor, is on hold in Phase III trials. A combination of medical treatment and hair transplant surgery has shown superior efficacy.
[TAKE-HOME MESSAGE] Androgenetic alopecia is a progressive condition and although the current available treatments are effective in arresting the progression of the disease, they allow only partial regrowth of hair at its best. Early treatment achieves the best desirable outcome.
Androgenetic alopecia is a progressive condition and although the current available treatments are effective in arresting the progression of the disease, they allow only partial regrowth of hair at it
APA 7
Rathnayake, D., & Sinclair, R. (2010). Male androgenetic alopecia.. Expert opinion on pharmacotherapy, 11(8), 1295-304. https://doi.org/10.1517/14656561003752730
Vancouver
Rathnayake D, Sinclair R. Male androgenetic alopecia. Expe. opin. phar.. 2010;11(8):1295-304. doi:10.1517/14656561003752730
AMA 11
Rathnayake D, Sinclair R. Male androgenetic alopecia. Expe. opin. phar.. 2010;11(8):1295-304. doi:10.1517/14656561003752730
Chicago
Rathnayake, D., and Sinclair, R.. 2010. "Male androgenetic alopecia." Expert opinion on pharmacotherapy 11 (8): 1295-304. https://doi.org/10.1517/14656561003752730
MLA 9
Rathnayake, D., and Sinclair R. "Male androgenetic alopecia." Expert opinion on pharmacotherapy, vol. 11, no. 8, 2010, pp. 1295-304. doi:10.1517/14656561003752730.
PMID
20426708 ↗
🏷️ 키워드 / MeSH 📖 같은 키워드 OA만
인용 관계
그래프 OA 노드: 8/8 (100%)
· 참조 0편 · 후속 8편
이 논문을 인용한 후속 연구 20
- Treatment options for androgenetic alopecia: Efficacy, side effects, compliance, financial considera…
- Treatment of Androgenetic Alopecia: Current Guidance and Unmet Needs.
- Polygonum multiflorum extract support hair growth by elongating anagen phase and abrogating the effe…
- Deciphering the molecular mechanisms of stem cell dynamics in hair follicle regeneration.
- Immunohistochemical evaluation of androgen receptor and nerve structure density in human prepuce fro…
- Compliance to Topical Minoxidil and Reasons for Discontinuation among Patients with Androgenetic Alo…
- Finasteride nano-transferosomal gel formula for management of androgenetic alopecia: ex vivo investi…
- A Pilot Study to Evaluate Effectiveness of Botulinum Toxin in Treatment of Androgenetic Alopecia in …
- Hair Loss and Telogen Effluvium Related to COVID-19: The Potential Implication of Adipose-Derived Me…
- Effectiveness of a Layer-by-Layer Microbubbles-Based Delivery System for Applying Minoxidil to Enhan…
- Efficacy of Platelet-Rich Plasma and Concentrated Growth Factor in Treating Androgenetic Alopecia - …
- Minoxidil Downregulates Interleukin-1 Alpha Gene Expression in HaCaT Cells.
- Application of multi-omics techniques to androgenetic alopecia: Current status and perspectives.
- Male-pattern hair loss: Comprehensive identification of the associated genes as a basis for understa…
- Targeting of the Pilosebaceous Follicle by Liquid Crystal Nanocarriers: In Vitro and In Vivo Effects…
- Design and in vitro evaluation of finasteride-loaded liquid crystalline nanoparticles for topical de…
- The psychosocial impact of alopecia in men: A mixed-methods survey study.
- Leaf Extract Promotes Hair Growth via Non-Receptor Tyrosine Kinase ACK1 Activation.
- Preclinical and Clinical Studies Demonstrate That the Proprietary Herbal Extract DA-5512 Effectively…
- Physcion, a novel inhibitor of 5α-reductase that promotes hair growth in vitro and in vivo.