Minoxidil use in dermatology, side effects and recent patents.
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TL;DR
The mechanism of action of Minoxidil, a vasodilator medication known for its ability to slow or stop hair loss and promote hair regrowth, and use in dermatology and some patents related to alternative treatment of allergic reactions due to its use are described.
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📑 인용한 논문 (6) ▾
- Oral Minoxidil for Alopecia Treatment: Risks, Benefits, and Recommendations. American journal of clinical dermatology · 2026
- Platelet-Rich Plasma Effectiveness in Treating Androgenetic Alopecia: A Comprehensive Eval… Cureus · 2025
- Research progress in the treatment of non-scarring alopecia: mechanism and treatment. Frontiers in pharmacology · 2025
- Drug-Induced Liver Failure Following Topical Minoxidil: A Case Report. Case reports in gastrointestinal medicine · 2025
- Expanding the therapeutic landscape of minoxidil for androgenetic alopecia: topical, oral … Frontiers in pharmacology · 2025
- Bicalutamide 25 mg combined with minoxidil 1 mg versus minoxidil 1 mg for female pattern h… JAAD international · 2025
연도별 인용 (2012–2026) · 합계 306
OpenAlex 토픽 ·
Hair Growth and Disorders
Dermatologic Treatments and Research
Contact Dermatitis and Allergies
Abstract 🌐 Abstract
Minoxidil, a vasodilator medication known for its ability to slow or stop hair loss and promote hair regrowth, was first introduced, exclusively as an oral drug, to treat high blood pressure. It was however discovered to have the important side-effect of increasing growth or darkening of fine body hairs; this led to the development of a topical formulation as a 2% concentration solution for the treatment of female androgenic alopecia or 5% for treating male androgenic alopecia. Measurable changes disappear within months after discontinuation of treatment. The mechanism by which it promotes hair growth is not fully understood. Minoxidil is a potassium channel opener, causing hyperpolarization of cell membranes and it is also a vasodilator, it is speculated that, by widening blood vessels and opening potassium channels, it allows more oxygen, blood and nutrients to the follicle. This can also cause follicles in the telogen phase to shed, usually soon to be replaced by new, thicker hairs in a new anagen phase. It needs to be applied regularly, once or twice daily, for hair gained to be maintained, and side effects are common. The most common adverse reactions of the topical formulation are limited to irritant and allergic contact dermatitis on the scalp. There have been cases of allergic reactions to the nonactive ingredient propylene glycol, which is found in some topical solution especially if they are galenic. Increased hair loss which can occur during Minoxidil use, is due to the synchronization of the hair cycle that the treatment induces. In this review, we described its mechanism of action, use in dermatology and some patents related to alternative treatment of allergic reactions due to its use.
The mechanism of action of Minoxidil, a vasodilator medication known for its ability to slow or stop hair loss and promote hair regrowth, and use in dermatology and some patents related to alternative
APA 7
Rossi, A., Cantisani, C., Melis, L., Iorio, A., Scali, E., & Calvieri, S. (2012). Minoxidil use in dermatology, side effects and recent patents.. Recent patents on inflammation & allergy drug discovery, 6(2), 130-6. https://doi.org/10.2174/187221312800166859
Vancouver
Rossi A, Cantisani C, Melis L, Iorio A, Scali E, Calvieri S. Minoxidil use in dermatology, side effects and recent patents. Rece. pate. infl. & alle. drug disc.. 2012;6(2):130-6. doi:10.2174/187221312800166859
AMA 11
Rossi A, Cantisani C, Melis L, Iorio A, Scali E, Calvieri S. Minoxidil use in dermatology, side effects and recent patents. Rece. pate. infl. & alle. drug disc.. 2012;6(2):130-6. doi:10.2174/187221312800166859
Chicago
Rossi, A., Cantisani, C., Melis, L., Iorio, A., Scali, E., and Calvieri, S.. 2012. "Minoxidil use in dermatology, side effects and recent patents." Recent patents on inflammation & allergy drug discovery 6 (2): 130-6. https://doi.org/10.2174/187221312800166859
MLA 9
Rossi, A., et al. "Minoxidil use in dermatology, side effects and recent patents." Recent patents on inflammation & allergy drug discovery, vol. 6, no. 2, 2012, pp. 130-6. doi:10.2174/187221312800166859.
PMID
22409453 ↗
🏷️ 키워드 / MeSH 📖 같은 키워드 OA만
인용 관계
그래프 OA 노드: 7/8 (88%)
· 참조 0편 · 후속 7편
이 논문을 인용한 후속 연구 20
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