Chemotherapy-induced alopecia.
4/5 보강
TL;DR
Among the few agents that have been evaluated so far in humans, AS101 and minoxidil were able to reduce the severity or shorten the duration of CIA, but could not prevent CIA.
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📑 인용한 논문 (6) ▾
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연도별 인용 (2012–2026) · 합계 192
OpenAlex 토픽 ·
Hair Growth and Disorders
Chemotherapy-related skin toxicity
Dermatologic Treatments and Research
Abstract 🌐 Abstract
Few dermatologic conditions carry as much emotional distress as chemotherapy-induced alopecia (CIA). The prerequisite for successful development of strategies for CIA prevention is the understanding of the pathobiology of CIA. The incidence and severity of CIA are variable and related to the particular chemotherapeutic protocol. CIA is traditionally categorized as acute diffuse hair loss caused by dystrophic anagen effluvium; however, CIA presents with different clinical patterns of hair loss. When an arrest of mitotic activity occurs, obviously numerous and interacting factors influence the shedding pattern. The major approach to minimize CIA is by scalp cooling. Unfortunately, most published data on scalp cooling are of poor quality. Several experimental approaches to the development of pharmacologic agents are under evaluation and include drug-specific antibodies, hair growth cycle modifiers, cytokines and growth factors, antioxidants, inhibitors of apoptosis, and cell-cycle and proliferation modifiers. Ultimately, the protection should be selective to the hair follicle; for example, topical application, such that the anticancer efficacy of chemotherapy is not hampered. Among the few agents that have been evaluated so far in humans, AS101 and minoxidil were able to reduce the severity or shorten the duration of CIA, but could not prevent CIA.
Among the few agents that have been evaluated so far in humans, AS101 and minoxidil were able to reduce the severity or shorten the duration of CIA, but could not prevent CIA.
APA 7
RM, T. (2009). Chemotherapy-induced alopecia.. Seminars in cutaneous medicine and surgery, 28(1), 11-4. https://doi.org/10.1016/j.sder.2008.12.001
Vancouver
RM T. Chemotherapy-induced alopecia. Semi. cuta. medi. surg.. 2009;28(1):11-4. doi:10.1016/j.sder.2008.12.001
AMA 11
RM T. Chemotherapy-induced alopecia. Semi. cuta. medi. surg.. 2009;28(1):11-4. doi:10.1016/j.sder.2008.12.001
Chicago
RM, T.. 2009. "Chemotherapy-induced alopecia." Seminars in cutaneous medicine and surgery 28 (1): 11-4. https://doi.org/10.1016/j.sder.2008.12.001
MLA 9
RM, T.. "Chemotherapy-induced alopecia." Seminars in cutaneous medicine and surgery, vol. 28, no. 1, 2009, pp. 11-4. doi:10.1016/j.sder.2008.12.001.
PMID
19341937 ↗
🏷️ 키워드 / MeSH 📖 같은 키워드 OA만
인용 관계
그래프 OA 노드: 7/8 (88%)
· 참조 0편 · 후속 7편
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