A Novel Multi-Targeting Approach to Treating Hair Loss, Using Standardized Nutraceuticals.

Journal of drugs in dermatology : JDD 2017 Vol.16(11) p. s141-s148

Farris PK, Rogers N, McMichael A, Kogan S

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Abstract

<p>Hair loss is a complicated problem that causes significant concern for those who are affected. Patients seeking medical treatment have limited options that include topical minoxidil and oral finasteride. While these treatments are backed by long term clinical use and research outcomes, many patients find topical minoxidil difficult to incorporate into their daily routine and some are concerned with the side effects associated with finasteride. In the office setting, patients may be treated with more invasive procedures such as platelet-rich plasma injections (PRP) and hair transplantation, treatments that often must be repeated and can lead to a costly investment. Consumers are increasingly interested in natural treatments for hair loss. Many turn to basic supplements only to be disappointed when they fail to deliver due to lack of standardization and efficacy. In this paper we review the benefits of a nutraceutical containing a specific blend of highly purified, standardized, bio-optimized, and bioavailable botanical extracts to treat hair loss. These phytoactives were selected because of their diverse multi-modal biologic activity against inflammation, DHT, stress mediators, oxidative damage, and intermediary signaling cascades. This supplement represents a paradigm shift as it addresses not only the factors that trigger hair loss but the downstream mediators of inflammation as well. Multi-center clinical studies are currently underway to confirm the efficacy and benefits of this unique nutraceutical.</p> <p><em>J Drugs Dermatol. 2017;16(11 Suppl):s141-148.</em></p>.

추출된 의학 개체 (NER)

유형영어 표현한국어 / 풀이UMLS CUI출처등장
시술 hair transplantation 모발이식 dict 1
해부 oral finasteride scispacy 1
해부 platelet-rich plasma scispacy 1
해부 hair scispacy 1
해부 extracts scispacy 1
약물 DHT C0038148
Dihydrotestosterone
scispacy 1
약물 bioavailable scispacy 1
약물 minoxidil C0026196
minoxidil
scispacy 1
약물 finasteride C0060389
finasteride
scispacy 1
약물 platelet-rich C0370220
Platelet rich plasma
scispacy 1
약물 PRP → platelet-rich plasma injections scispacy 1
질환 hair loss C0002170
Alopecia
scispacy 1
질환 inflammation C0021368
Inflammation
scispacy 1
기타 Hair scispacy 1
기타 Patients scispacy 1
기타 PRP → platelet-rich plasma injections scispacy 1

MeSH Terms

Alopecia; Dietary Supplements; Evidence-Based Medicine; Humans

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