Botulinum Toxin Type A for Pediatric Torticollis: A Review of Clinical Research.
TL;DR
Results support BoNT-A as a valuable therapeutic option for refractory pediatric torticollis, warranting integration into multidisciplinary care frameworks, and variability in dosing, injection protocols, and follow-up durations underscores the need for standardized treatment guidelines and further high-quality research.
OpenAlex 토픽 ·
Craniofacial Disorders and Treatments
Botulinum Toxin and Related Neurological Disorders
Temporomandibular Joint Disorders
Results support BoNT-A as a valuable therapeutic option for refractory pediatric torticollis, warranting integration into multidisciplinary care frameworks, and variability in dosing, injection protoc
APA
Na-Yoen Kwon, Soo-Hyun Sung, Hyun-Kyung Sung (2025). Botulinum Toxin Type A for Pediatric Torticollis: A Review of Clinical Research.. Toxins, 17(11). https://doi.org/10.3390/toxins17110543
MLA
Na-Yoen Kwon, et al.. "Botulinum Toxin Type A for Pediatric Torticollis: A Review of Clinical Research.." Toxins, vol. 17, no. 11, 2025.
PMID
41295858
Abstract
Pediatric torticollis, predominantly resulting from congenital muscular torticollis, is characterized by unilateral shortening of the sternocleidomastoid muscle, leading to head tilt and limited cervical mobility. Conventional management primarily involves physical therapy and repositioning strategies, with most infants achieving full recovery. However, a subset of patients exhibits persistent symptoms despite conservative treatment. Botulinum toxin type A (BoNT-A) has emerged as a minimally invasive adjunct intervention that targets muscular hypertonicity by inhibiting acetylcholine release at neuromuscular junctions. This scoping review synthesizes clinical evidence from six studies, including randomized controlled trials and case reports, assessing the efficacy and safety of BoNT-A in pediatric torticollis. Results indicate consistent improvements in range of motion, head posture correction, and patient satisfaction, with rare and mild adverse events such as local bruising and transient muscle weakness. Despite promising outcomes, variability in dosing, injection protocols, and follow-up durations underscores the need for standardized treatment guidelines and further high-quality research. These findings support BoNT-A as a valuable therapeutic option for refractory pediatric torticollis, warranting integration into multidisciplinary care frameworks.
추출된 의학 개체 (NER)
| 유형 | 영어 표현 | 한국어 / 풀이 | UMLS CUI | 출처 | 등장 |
|---|---|---|---|---|---|
| 시술 | botulinum toxin
|
보툴리눔독소 주사 | dict | 2 | |
| 해부 | muscular
|
scispacy | 1 | ||
| 해부 | sternocleidomastoid muscle
|
scispacy | 1 | ||
| 해부 | cervical
|
scispacy | 1 | ||
| 해부 | neuromuscular junctions
|
scispacy | 1 | ||
| 해부 | muscle
|
scispacy | 1 | ||
| 합병증 | head
|
scispacy | 1 | ||
| 합병증 | head posture
|
scispacy | 1 | ||
| 약물 | acetylcholine
|
C0001041
acetylcholine
|
scispacy | 1 | |
| 질환 | Torticollis
|
C0040485
Torticollis
|
scispacy | 1 | |
| 질환 | congenital muscular torticollis
|
C0079352
Congenital torticollis
|
scispacy | 1 | |
| 질환 | bruising
|
C0009938
Contusions
|
scispacy | 1 | |
| 질환 | muscle weakness
|
C0030552
Paresis
|
scispacy | 1 | |
| 기타 | Botulinum Toxin Type A
|
scispacy | 1 | ||
| 기타 | BoNT-A
→ Botulinum toxin type A
|
scispacy | 1 |
MeSH Terms
Torticollis; Humans; Botulinum Toxins, Type A; Neuromuscular Agents; Child; Treatment Outcome
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