The growth of human scalp hair mediated by visible red light laser and LED sources in males.
무작위 임상시험
4/5 보강
TL;DR
A double‐blind randomized controlled trial was undertaken to define the safety and physiologic effects of LLLT on males with androgenic alopecia.
PICO 자동 추출 (휴리스틱, conf 3/4)
유사 논문P · Population 대상 환자/모집단
환자: a very high baseline count and a very large decrease, resulted in baseline hair counts of 151
I · Intervention 중재 / 시술
a "TOPHAT655" unit containing 21, 5 mW lasers (655 ± 5 nm), and 30 LEDS (655 ± 20 nm), in a bicycle-helmet like apparatus
C · Comparison 대조 / 비교
추출되지 않음
O · Outcome 결과 / 결론
Post treatment hair counts were 158.2 ± 61.5 (N = 18) and 228.7 ± 102.8 (N = 22) (P = 0.011), resulting in a 35% percent increase in hair growth (32.3 ± 44.2, placebo, N = 18; 67.2 ± 33.4, active, N = 22) (P = 0.003). [CONCLUSIONS] LLLT of the scalp at 655 nm significantly improved hair counts in males with androgenetic alopecia.
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· 인용됨 27
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연도별 인용 (2013–2026) · 합계 157
OpenAlex 토픽 ·
Hair Growth and Disorders
Dermatologic Treatments and Research
Laser Applications in Dentistry and Medicine
Abstract 🌐 Abstract
[BACKGROUND AND OBJECTIVES] Low level laser therapy (LLLT) has been used to promote hair growth. A double-blind randomized controlled trial was undertaken to define the safety and physiologic effects of LLLT on males with androgenic alopecia.
[METHODS] Forty-four males (18-48 yo, Fitzpatrick I-IV, Hamilton-Norwood IIa-V) were recruited. A transition zone scalp site was selected; hairs were trimmed to 3 mm height; the area was tattooed and photographed. The active group received a "TOPHAT655" unit containing 21, 5 mW lasers (655 ± 5 nm), and 30 LEDS (655 ± 20 nm), in a bicycle-helmet like apparatus. The placebo group unit appeared identical, containing incandescent red lights. Patients treated at home every other day × 16 weeks (60 treatments, 67.3 J/cm(2) irradiance/25 minute treatment), with follow up and photography at 16 weeks. A masked 2.85 cm(2) photographic area was evaluated by another blinded investigator. The primary endpoint was the percent increase in hair counts from baseline.
[RESULTS] Forty-one patients completed the study (22 active, 19 placebo). No adverse events or side effects were reported. Baseline hair counts were 162.7 ± 95.9 (N = 22) in placebo and 142.0 ± 73.0 (N = 22) and active groups respectively (P = 0.426). Post Treatment hair counts were 162.4 ± 62.5 (N = 19) and 228.7 ± 102.8 (N = 22), respectively (P = 0.0161). A 39% percent hair increase was demonstrated (28.4 ± 46.2 placebo, N = 19; 67.2 ± 33.4, active, N = 22) (P = 0.001) Deleting one placebo group subject with a very high baseline count and a very large decrease, resulted in baseline hair counts of 151.1 ± 81.0 (N = 21) and 142.0 ± 73.0 (N = 22), respectively (P = 0.680). Post treatment hair counts were 158.2 ± 61.5 (N = 18) and 228.7 ± 102.8 (N = 22) (P = 0.011), resulting in a 35% percent increase in hair growth (32.3 ± 44.2, placebo, N = 18; 67.2 ± 33.4, active, N = 22) (P = 0.003).
[CONCLUSIONS] LLLT of the scalp at 655 nm significantly improved hair counts in males with androgenetic alopecia.
[METHODS] Forty-four males (18-48 yo, Fitzpatrick I-IV, Hamilton-Norwood IIa-V) were recruited. A transition zone scalp site was selected; hairs were trimmed to 3 mm height; the area was tattooed and photographed. The active group received a "TOPHAT655" unit containing 21, 5 mW lasers (655 ± 5 nm), and 30 LEDS (655 ± 20 nm), in a bicycle-helmet like apparatus. The placebo group unit appeared identical, containing incandescent red lights. Patients treated at home every other day × 16 weeks (60 treatments, 67.3 J/cm(2) irradiance/25 minute treatment), with follow up and photography at 16 weeks. A masked 2.85 cm(2) photographic area was evaluated by another blinded investigator. The primary endpoint was the percent increase in hair counts from baseline.
[RESULTS] Forty-one patients completed the study (22 active, 19 placebo). No adverse events or side effects were reported. Baseline hair counts were 162.7 ± 95.9 (N = 22) in placebo and 142.0 ± 73.0 (N = 22) and active groups respectively (P = 0.426). Post Treatment hair counts were 162.4 ± 62.5 (N = 19) and 228.7 ± 102.8 (N = 22), respectively (P = 0.0161). A 39% percent hair increase was demonstrated (28.4 ± 46.2 placebo, N = 19; 67.2 ± 33.4, active, N = 22) (P = 0.001) Deleting one placebo group subject with a very high baseline count and a very large decrease, resulted in baseline hair counts of 151.1 ± 81.0 (N = 21) and 142.0 ± 73.0 (N = 22), respectively (P = 0.680). Post treatment hair counts were 158.2 ± 61.5 (N = 18) and 228.7 ± 102.8 (N = 22) (P = 0.011), resulting in a 35% percent increase in hair growth (32.3 ± 44.2, placebo, N = 18; 67.2 ± 33.4, active, N = 22) (P = 0.003).
[CONCLUSIONS] LLLT of the scalp at 655 nm significantly improved hair counts in males with androgenetic alopecia.
- 표본수 (n) 22
- p-value P = 0.0161
- p-value P = 0.001
- 연구 설계 randomized controlled trial
A double‐blind randomized controlled trial was undertaken to define the safety and physiologic effects of LLLT on males with androgenic alopecia.
APA 7
Lanzafame, R. J., Blanche, R. R., Bodian, A. B., Chiacchierini, R. P., Fernandez-Obregon, A., & Kazmirek, E. R. (2013). The growth of human scalp hair mediated by visible red light laser and led sources in males.. Lasers in surgery and medicine, 45(8), 487-95. https://doi.org/10.1002/lsm.22173
Vancouver
Lanzafame RJ, Blanche RR, Bodian AB, Chiacchierini RP, Fernandez-Obregon A, Kazmirek ER. The growth of human scalp hair mediated by visible red light laser and LED sources in males. Lase. surg. medi.. 2013;45(8):487-95. doi:10.1002/lsm.22173
AMA 11
Lanzafame RJ, Blanche RR, Bodian AB, Chiacchierini RP, Fernandez-Obregon A, Kazmirek ER. The growth of human scalp hair mediated by visible red light laser and LED sources in males. Lase. surg. medi.. 2013;45(8):487-95. doi:10.1002/lsm.22173
Chicago
Lanzafame, R. J., Blanche, R. R., Bodian, A. B., Chiacchierini, R. P., Fernandez-Obregon, A., and Kazmirek, E. R.. 2013. "The growth of human scalp hair mediated by visible red light laser and LED sources in males." Lasers in surgery and medicine 45 (8): 487-95. https://doi.org/10.1002/lsm.22173
MLA 9
Lanzafame, R. J., et al. "The growth of human scalp hair mediated by visible red light laser and LED sources in males." Lasers in surgery and medicine, vol. 45, no. 8, 2013, pp. 487-95. doi:10.1002/lsm.22173.
PMID
24078483 ↗
🏷️ 키워드 / MeSH 📖 같은 키워드 OA만
인용 관계
그래프 OA 노드: 5/8 (63%)
· 참조 0편 · 후속 5편
이 논문을 인용한 후속 연구 20
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