Three players in the 'toxic affair' between botulinum neurotoxin type A and neurons.

Trends in neurosciences 2023 Vol.46(9) p. 695-697

Rossetto O, Pirazzini M, Montecucco C

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Abstract

Joensuu and colleagues have recently shown that botulinum neurotoxin (BoNT) type A exploits a heterotrimeric complex in the presynaptic membrane to bind to and enter neurons using a Trojan horse-like mechanism. Similar processes may be relevant to the neuronal entry of different botulinum toxin serotypes and other neuropathogens.

추출된 의학 개체 (NER)

유형영어 표현한국어 / 풀이UMLS CUI출처등장
시술 botulinum toxin 보툴리눔독소 주사 dict 1

MeSH Terms

Botulinum Toxins, Type A; Synaptic Vesicles; Membrane Glycoproteins; Nerve Tissue Proteins; Neurons

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