Alternative Clinical Indications of Botulinum Toxin.

American journal of clinical dermatology 2020 Vol.21(6) p. 855-880

Alster TS, Harrison IS

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Abstract

Botulinum toxin type A (BoNTA) is a powerful neurotoxin that inhibits acetylcholine release from presynaptic vesicles. The potency and safety profile of BoNTA grant the toxin vast therapeutic potential. It has been used off-label for a variety of dermatologic conditions. This review aims to analyze published literature regarding the benefits and risks of the off-label use of BoNTA beyond facial lines, including eccrine hidrocystomas, enlarged pores, keloids and hypertrophic scars, hidradenitis suppurativa, hyperhidrosis, masseter muscle hypertrophy, and salivary gland hypertrophy, among others. A MEDLINE search from January 2000 to December 2019 was conducted on the off-label uses of botulinum toxin in dermatology.

추출된 의학 개체 (NER)

유형영어 표현한국어 / 풀이UMLS CUI출처등장
시술 botulinum toxin 보툴리눔독소 주사 dict 3

MeSH Terms

Acetylcholine Release Inhibitors; Botulinum Toxins, Type A; Cicatrix, Hypertrophic; Dermatology; Hidradenitis Suppurativa; Hidrocystoma; Humans; Hyperhidrosis; Hypertrophy; Injections, Intralesional; Injections, Subcutaneous; Keloid; Masseter Muscle; Off-Label Use; Randomized Controlled Trials as Topic; Salivary Glands; Sweat Gland Neoplasms; Treatment Outcome

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