Case reports on hand prejuvenation: clinical outcomes in middle-aged women with hyaluronic acid filler plus lidocaine.

[BACKGROUND] Hand rejuvenation with hyaluronic acid filler injections is gaining more attention for its ability to correct volume loss and improve skin quality. The hand dorsum is prone to loss of dermal elasticity and subcutaneous atrophy as individuals age, and administering hyaluronic acid fillers has become an option to restore the smoothness and youthful contour of the hand.

[OBJECTIVE] The aim of this study is to demonstrate that injections with Definisse Touch Filler Plus Lidocaine are effective and safe for hand rejuvenation.

[METHODS] Ten subjects underwent filler placement of 0.5 to 1.0 mL in the dorsal superficial lamina, which is devoid of sensory nerves and major skin vessels, using a blunt cannula via the fanning technique. Measurements were done before, immediately after, and 1 month after the treatment using validated aesthetic scales.

[RESULTS] There was a significant correction of volume loss immediately after the first treatment and an improvement in skin texture and topography 1 month after the procedure. No lasting or severe adverse effects were observed.

[LIMITATIONS] To show significant and conclusive results, it is recommended to conduct further prospective, comparative, blinded studies in more subjects followed for longer periods (ie, 12 months or more). Objective analysis of volumetric changes using automated three-dimensional surface techniques is likewise beneficial.

[CONCLUSION] Injecting a low G-prime hyaluronic acid along the dorsal superficial lamina via cannula provides an effective and tolerable option for improving the appearance of aged hands.