Preoperative Care Clinic Improves Survival for Patients Undergoing Free-Flap Reconstruction.

Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery 2025 Vol.173(5) p. 1121-1130

Harley RJ, Esper SA, Cheng TZ, Eljamri S, Velu P, Solari MG, Sridharan SS, Kubik M, Kim S

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Abstract

[OBJECTIVE] This study aims to evaluate whether perioperative care improves postoperative outcomes for head and neck reconstruction patients with preexisting health conditions.

[STUDY DESIGN] Retrospective cohort study.

[SETTING] Single tertiary academic center between 2013 and 2021.

[METHODS] This study included adult patients who underwent free-flap reconstruction for head and neck cancer. Patients who received perioperative care were compared with patients who received our institution's standard of care. Comorbid health conditions were measured using the Charlson comorbidity index (CCI) excluding solid tumors. Primary outcomes were major and minor complications, length of hospital stay (LOS), days in intensive care unit (ICU), discharge to acute/subacute facility, hospital-free days, and overall survival (OS). Interaction models were specified to evaluate the impact of preoperative care with respect to CCI.

[RESULTS] Of the 148 patients included, 83 received perioperative care and 65 received institutional standard of care (mean [SD]: age, 62.1 [10.8]; male, 100 [67.6%]; CCI   4, 43 [29.1%]). Patients with higher CCI who received perioperative care spent fewer days in the hospital (CCI 3: coefficient [ , -5.50; P = .012 and CCI   4: , -6.41; P = .022) and ICU (CCI 3: , -2.90; P = .002 and CCI   4: , -6.54; P = .001), gained more hospital-free days (CCI   4: , 17.00; P = .002), and had improved OS (CCI   4: adjusted hazard ratio [aHR], 0.14; P = .023). Perioperative care was not significantly associated with lower rates of major and minor complications or placement at a facility.

[CONCLUSION] Perioperative care provides a robust benefit for patients with medical comorbidities undergoing head and neck reconstruction, but this effect incrementally decreases for healthier patients.

추출된 의학 개체 (NER)

유형영어 표현한국어 / 풀이UMLS CUI출처등장
시술 flap 피판재건술 dict 2
약물 [OBJECTIVE] scispacy 1
약물 [29.1%]) scispacy 1
약물 [aHR] scispacy 1
질환 head and neck reconstruction scispacy 1
질환 head and neck cancer C0278996
Malignant Head and Neck Neoplasm
scispacy 1
질환 comorbidity C0009488
Comorbidity
scispacy 1
질환 tumors C0027651
Neoplasms
scispacy 1
질환 head and neck scispacy 1
질환 solid tumors scispacy 1
질환 LOS → length of hospital stay scispacy 1
기타 Patients scispacy 1
기타 Free-Flap scispacy 1
기타 CCI → Charlson comorbidity index scispacy 1

MeSH Terms

Humans; Male; Female; Retrospective Studies; Middle Aged; Plastic Surgery Procedures; Free Tissue Flaps; Head and Neck Neoplasms; Preoperative Care; Length of Stay; Aged; Postoperative Complications; Survival Rate

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