The effect of preoperative oral carbohydrate on the perioperative period of fibula free flap surgery in patients with oral cancer: a retrospective study.

Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer 2025 Vol.33(10) p. 836

Liu C, Liu X, Zhou M, Yao J, Zhang S, Zhao T

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Abstract

[OBJECTIVE] This study examines the effects of preoperative oral carbohydrates on the perioperative period of Fibula Free Flap surgery in oral cancer patients, aiming to enhance postoperative recovery.

[METHODS] The study involved 89 patients who underwent fibula flap reconstruction surgery from January to December 2023. Patients were divided into control and experimental groups based on admission time. The control group followed standard fasting guidelines, while the experimental group received 800 mL and 200 mL of carbohydrates solution orally at 10 and 2 h pre-surgery, respectively. Data collected for both groups included comfort levels, blood glucose, surgical duration, intraoperative blood loss, fluid replacement, albumin, prealbumin, hemoglobin, PCT, IL-6, flap crisis, wound infection, bleeding, thrombosis, gastrointestinal reactions, extubation time, hospital stay, and total cost. All data were statistically analyzed.

[RESULTS] The experimental group reported significantly lower thirst and hunger one hour pre-surgery (p < 0.0001) and had lower blood glucose levels one day post-surgery (p = 0.0003) compared to the control group. No significant differences were observed in other preoperative or postoperative measures.

[CONCLUSIONS] Preoperative oral carbohydrates improve comfort and stabilize blood glucose levels in patients undergoing oral cancer fibula flap surgery, positively influencing perioperative management. This approach is beneficial for patients receiving this type of surgery.

추출된 의학 개체 (NER)

유형영어 표현한국어 / 풀이UMLS CUI출처등장
시술 flap 피판재건술 dict 3
시술 free flap 피판재건술 dict 2
해부 oral scispacy 1
해부 blood glucose scispacy 1
해부 blood scispacy 1
해부 oral carbohydrates scispacy 1
합병증 wound infection 감염 dict 1
합병증 wound scispacy 1
합병증 gastrointestinal scispacy 1
약물 carbohydrate C0007004
Carbohydrates
scispacy 1
약물 oral cancer C0153381
Malignant neoplasm of mouth
scispacy 1
약물 glucose C0017725
glucose
scispacy 1
약물 [OBJECTIVE] scispacy 1
약물 carbohydrates scispacy 1
약물 [CONCLUSIONS] scispacy 1
질환 oral cancer C0153381
Malignant neoplasm of mouth
scispacy 1
질환 intraoperative blood loss scispacy 1
질환 infection C0009450
Communicable Diseases
scispacy 1
질환 bleeding C0019080
Hemorrhage
scispacy 1
질환 thrombosis C0040053
Thrombosis
scispacy 1
질환 gastrointestinal reactions scispacy 1
질환 thirst C0039971
Thirst
scispacy 1
질환 lower blood glucose scispacy 1
질환 oral cancer fibula flap surgery scispacy 1
질환 oral cancer patients scispacy 1
질환 oral cancer fibula flap scispacy 1
기타 fibula free flap scispacy 1
기타 patients scispacy 1
기타 fibula flap scispacy 1
기타 albumin scispacy 1
기타 prealbumin scispacy 1
기타 hemoglobin scispacy 1
기타 IL-6 scispacy 1

MeSH Terms

Humans; Female; Male; Retrospective Studies; Middle Aged; Free Tissue Flaps; Mouth Neoplasms; Aged; Preoperative Care; Fibula; Blood Glucose; Adult; Perioperative Period; Plastic Surgery Procedures; Dietary Carbohydrates

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