Current Approaches Including Novel Nano/Microtechniques to Reduce Silicone Implant-Induced Contracture with Adverse Immune Responses.

International journal of molecular sciences 2018 Vol.19(4)

Kang SH, Sutthiwanjampa C, Heo CY, Kim WS, Lee SH, Park H

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Abstract

Capsular contracture, which is the pathologic development of fibrous capsules around implants, is a major complication of reconstructive and aesthetic breast surgeries. Capsular contracture can cause implant failure with breast hardening, deformity, and severe pain. The exact mechanisms underlying this complication remain unclear. In addition, anaplastic large cell lymphoma is now widely recognized as a very rare disease associated with breast implants. Foreign body reactions are an inevitable common denominator of capsular contracture. A number of studies have focused on the associated immune responses and their regulation. The present article provides an overview of the currently available techniques, including novel nano/microtechniques, to reduce silicone implant-induced contracture and associated foreign body responses.

추출된 의학 개체 (NER)

유형영어 표현한국어 / 풀이UMLS CUI출처등장
해부 breast 유방 dict 3
합병증 capsular contracture 피막구축 dict 3
재료 silicone implant 실리콘 보형물 dict 2
해부 Silicone scispacy 1
합병증 anaplastic large cell lymphoma 보형물연관 역형성대세포림프종 dict 1
약물 Silicone C0037114
silicones
scispacy 1
질환 fibrous C0439709
Fibrous
scispacy 1
질환 implant failure C0854676
Implant Failure
scispacy 1
질환 pain C0030193
Pain
scispacy 1
질환 anaplastic C0205618
Undifferentiated
scispacy 1
질환 Contracture C0009917
Contracture
scispacy 1

MeSH Terms

Animals; Biomimetic Materials; Breast Implants; Female; Foreign-Body Reaction; Humans; Implant Capsular Contracture; Lymphoma, Large-Cell, Anaplastic; Nanotechnology; Silicone Gels

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