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A Pilot One and Two-Year Prospective, Blinded Clinical Evaluation of Efficacy, and Safety of Combined Treatment With Crosslinked Hyaluronic Acid Dermal Filler and Barbed Polydioxanone Suspension Threads for Mid-Face Contour Enhancement.
[INTRODUCTION] The combination of hyaluronic acid (HA) fillers and polydioxanone (PDO) thread lifting is gaining popularity for mid-face rejuvenation, especially among the Asian population. Despite the common use of these techniques, there …
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A multipathogen DNA vaccine elicits protective immune responses against two class A bioterrorism agents, anthrax and botulism.
The potential use of biological agents has become a major public health concern worldwide. According to the CDC classification, Bacillus anthracis and Clostridium botulinum, the bacterial pathogens that cause anthrax and botulism, respectiv…
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Morin Disrupts Cytoskeleton Reorganization in Osteoclasts through an ROS/SHP1/c-Src Axis and Grants Protection from LPS-Induced Bone Loss.
Morin is a naturally occurring flavonoid with anti-inflammatory and antioxidative properties. Therefore, we hypothesized that morin may prevent inflammatory bone loss by reducing oxidative stress. To investigate the effect of morin on infla…
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Pan-Asian Consensus on Calcium Hydroxyapatite for Skin Biostimulation, Contouring, and Combination Treatments.
[BACKGROUND] Several usage guidelines for calcium hydroxylapatite (CaHA), a dermal filler material, exist for non-Asian patients, making it necessary to determine whether their findings and consensuses are applicable to Asian patients who h…
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Factors influencing long-term treatment response to botulinum toxin injection for spasmodic dysphonia.
[OBJECTIVE] The purpose of this study was to evaluate the outcomes of long-term botulinum toxin type A (BoNTA) treatment for adductor spasmodic dysphonia (AdSD) and to determine the factors predictive of treatment response by investigating …
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Alternating Unilateral Versus Bilateral Injections of Botulinum Toxin for the Treatment of Adductor Spasmodic Dysphonia.
[OBJECTIVE] This study aimed to compare the long-term efficacy, durability, and dose and interval stability between alternating unilateral and bilateral injections of botulinum neurotoxin type A for the treatment of adductor spasmodic dysph…
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Estrogen Decreases Cytoskeletal Organization by Forming an ERα/SHP2/c-Src Complex in Osteoclasts to Protect against Ovariectomy-Induced Bone Loss in Mice.
Loss of ovarian function is closely related to estrogen (E) deficiency, which is responsible for increased osteoclast (OC) differentiation and activity. We aimed to investigate the action mechanism of E to decrease bone resorption in OCs to…
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Comparative efficacy of bariatric endoscopic procedures in the treatment of morbid obesity: a systematic review and network meta-analysis.
[BACKGROUND] The comparative efficacy of bariatric endoscopic procedures has not been completely elucidated. We aimed to comprehensively evaluate the efficacy of bariatric endoscopic procedures. [METHODS] We searched for randomized control…
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Ophthalmologic Complications Associated With Oculofacial Plastic and Esthetic Surgeries.
[PURPOSE] To assess the ophthalmologic complications after oculofacial plastic and esthetic surgeries, including their incidence and management. [METHODS] A retrospective study was performed on 110 patients who presented with ocular compli…
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Bioimaging of botulinum toxin and hyaluronate hydrogels using zwitterionic near-infrared fluorophores.
[BACKGROUND] The injection of botulinum toxin (BTX) to reduce facial wrinkles is one of the most frequently performed plastic surgery procedures. The biocompatible hydrogels are injected with BTX for effective tissue augmentation. However, …
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Asymmetry of Preoperative Incision Design Markings for Upper Blepharoplasty.
[PURPOSE] To compare preoperative incision design markings between both eyelids in upper blepharoplasty. [METHODS] This retrospective study examined 22 patients who underwent bilateral upper blepharoplasty surgery resulting from senile der…
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Modifying the upper eyelid crease in Asian patients with hyaluronic acid fillers.
[BACKGROUND] Preliminary experience with the use of hyaluronic acid fillers as a nonsurgical alternative in the management of upper eyelid crease asymmetry and superior sulcus hollowing in Asian patients has proven promising. [METHODS] Thi…