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A Pilot One and Two-Year Prospective, Blinded Clinical Evaluation of Efficacy, and Safety of Combined Treatment With Crosslinked Hyaluronic Acid Dermal Filler and Barbed Polydioxanone Suspension Threads for Mid-Face Contour Enhancement.
[INTRODUCTION] The combination of hyaluronic acid (HA) fillers and polydioxanone (PDO) thread lifting is gaining popularity for mid-face rejuvenation, especially among the Asian population. Despite the common use of these techniques, there …
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Is There a Correlation Between Masticatory Muscle Thickness and Pain After Botulinum Toxin Injections in Myogenic TMD Patients?: A Pilot Study.
Botulinum toxin type A (BoNT-A), a potent neurotoxin, is increasingly used to treat myogenic temporomandibular disorders (TMDs); however, the interplay between muscle atrophy and pain relief remains incompletely understood. This pilot study…
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Anatomy-based Filler Injection: Diagnosis to Treatment Techniques for the Glabellar Region.
Glabellar filler injections are a popular non-surgical approach to address depressions and wrinkles caused by aging, muscle activity, and soft tissue loss. An anatomy-based technique emphasizes understanding the complex structure of the gla…
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Direct muscular connection between the orbicularis oculi and risorius muscles: a case report.
[PURPOSE] The orbicularis oculi (OOc) and risorius muscles are typically regarded as distinct anatomic and functional units with no known direct muscular connections. Although rare variants of the facial musculature have been reported, thei…
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Anatomical courses of the deep and superficial septal branches of the superior labial artery in the columella and nasal tip for use in clinical rhinoplasty and reconstructive surgeries.
[PURPOSE] Understanding the detailed course of the septal branch of the superior labial artery is crucial for improving the safety and efficacy of both invasive and noninvasive nasal procedures. This study aimed to clarify the anatomical co…
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Is multiple wavelength diode laser for facial contouring safe?
The multiple wavelength diode laser (MWDL) is a sophisticated device designed to target deeper skin layers by emitting various wavelengths. Its unique feature is the ability to deliver heat to specific depths within the tissue using differe…
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Does injecting small amounts of fillers prevent the development of secondary blindness?
[INTRODUCTION] Inadvertent entry of filler products into the supratrochlear, supraorbital, or dorsal nasal arteries, among other branches of the ophthalmic artery, might result in an immediate and devastating loss of vision. We wanted to ex…
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Self-crossing hyaluronic acid filler with combination use of polydioxanone thread in minipig model.
[INTRODUCTION] The advances of self-crossing hyaluronic acid (SC-HA) fillers combination use with polydioxanone thread in minipigs were examined for compatibility, effectiveness, and immune response. [MATERIALS AND METHODS] A 12-week exper…
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Assessment of current practices and perceived effectiveness of injectable polynucleotide for enlarged facial pores among cosmetic physicians: A survey-based evaluation.
[BACKGROUND] Polynucleotides stimulate collagen formation and are used clinically to enhance elasticity. In this study, we investigated current practices and perceived effectiveness of polynucleotide injection treatment for enlarged facial …
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Anatomical Trajectory of the Corrugator Supercilii Muscle in Koreans: Implications for Aesthetic and Clinical Practices.
[BACKGROUND] Understanding the attachment patterns of the corrugator supercilii (CS) muscle is vital for treatments designed to improve facial symmetry and functionality. [OBJECTIVES] The aim of this research was to elucidate the anatomica…
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Anatomical Study of the Superficial Musculoaponeurotic System in Relation to the Zygomaticus Major.
[BACKGROUND] The superficial musculoaponeurotic system (SMAS) is crucial for the structural integrity and dynamics of facial expressions and is a particularly important consideration during facelift surgeries. This study investigated the an…
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The Renaissance of Male Infertility Management in the Golden Age of Andrology.
Infertility affects nearly 186 million people worldwide and the male partner is the cause in about half of the cases. Meta-regression data indicate an unexplained decline in sperm concentration and total sperm count over the last four decad…
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Anatomical proposal of local anesthesia injection for median nerve block in treating hyperhidrosis with botulinum neurotoxin.
[INTRODUCTION] Hyperhidrosis, causing excessive sweat, can be treated with Botulinum neurotoxin injection. Botulinum toxin, an effective and safe treatment for hyperhidrosis, unfortunately involves significant pain due to multiple injection…
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Morin Disrupts Cytoskeleton Reorganization in Osteoclasts through an ROS/SHP1/c-Src Axis and Grants Protection from LPS-Induced Bone Loss.
Morin is a naturally occurring flavonoid with anti-inflammatory and antioxidative properties. Therefore, we hypothesized that morin may prevent inflammatory bone loss by reducing oxidative stress. To investigate the effect of morin on infla…
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Positional deformation of the parotid gland: Application to minimally invasive procedures.
Anatomical studies of the parotid gland are important for mid- and lower face filler, botulinum toxin, and thread lifting procedures. The purpose of this study was to observe the topographic anatomy of the parotid gland using cadaveric diss…
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Estrogen Decreases Cytoskeletal Organization by Forming an ERα/SHP2/c-Src Complex in Osteoclasts to Protect against Ovariectomy-Induced Bone Loss in Mice.
Loss of ovarian function is closely related to estrogen (E) deficiency, which is responsible for increased osteoclast (OC) differentiation and activity. We aimed to investigate the action mechanism of E to decrease bone resorption in OCs to…
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Intraoperative botulinum toxin injection for superficial partial parotidectomy: A prospective pilot study.
[OBJECTIVES] Sialocele and salivary fistula are not serious but troublesome complications after parotidectomy. Various modalities have been introduced to prevent postoperative saliva-related complications. However, clinical trials assessing…
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Sonographic Analysis of the Upper Labial Orbicularis Oris and Its Clinical Implications.
[BACKGROUND] Purse string lips, which include the vertical wrinkles over the lips, are frequently observed in aged individuals. Botulinum toxin and fillers are routinely injected into these areas to remove the wrinkles; however, the anatomy…
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Celiac plexus block with botulinum toxin in severe chronic pancreatitis-A case report.
[WHAT IS KNOWN AND OBJECTIVE] The botulinum toxin (BoNT) has been widely used for various conditions associated with pain. [CASE DESCRIPTION] Here, we report a case where celiac plexus block (CPB) with BoNT relieved intractable chronic pan…
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A novel anatomical consideration on the exposed segment of the facial artery.
An understanding of the location and depth of the facial artery (FA) is essential in aesthetic surgery and various cosmetic procedures. The purpose of this study was to clarify the three-dimensional (3D) topography of the exposed segment (E…
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Prolonged, acute suppression of cysteinyl leukotriene to reduce capsular contracture around silicone implants.
[UNLABELLED] We hypothesize that periodically early, local suppression of cysteinyl leukotrienes (CysLTs), which are potent inflammatory mediators, can reduce the fibrotic capsular contracture around silicone implants. We tested this hypoth…
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A pilot study of the efficacy of the POLARGEN ultrahigh-frequency electric field (40.68 MHz) radiofrequency device in the treatment of facial contouring.
[BACKGROUND] Various radiofrequency (RF) devices are used to treat skin laxity and face contouring, but few studies have examined ultrahigh-frequency (UHF) electric field (40.68 MHz) RF devices. [OBJECTIVE] To evaluate the efficacy and saf…
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Botulinum Toxin for the Treatment of Neuropathic Pain.
Botulinum toxin (BoNT) has been used as a treatment for excessive muscle stiffness, spasticity, and dystonia. BoNT for approximately 40 years, and has recently been used to treat various types of neuropathic pain. The mechanism by which BoN…
- Allogeneic Hair Transplantation with Enhanced Survival by Anti-ICAM-1 Antibody with Short-Term Rapamycin Treatment in Nonhuman Primates.
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Functional and cosmetic outcomes of robot-assisted neck dissection by a postauricular facelift approach for head and neck cancer.
[OBJECTIVES] The purpose of this study was to compare the functional and cosmetic outcomes of robot-assisted neck dissection with those of conventional neck dissection. [MATERIALS AND METHODS] We prospectively analyzed 113 patients with he…
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Effects of the Ultra-High-Frequency Electrical Field Radiofrequency Device on Mouse Skin: A Histologic and Molecular Study.
[BACKGROUND] Radiofrequency technology is one of the most recently developed methods for noninvasive skin tightening and facial contouring, and works by generating thermal energy in the deep dermis. Although clinical improvements have been …
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Ultrasound-Guided Nerve Block with Botulinum Toxin Type A for Intractable Neuropathic Pain.
Neuropathic pain includes postherpetic neuralgia (PHN), painful diabetic neuropathy (PDN), and trigeminal neuralgia, and so on. Although various drugs have been tried to treat neuropathic pain, the effectiveness of the drugs sometimes may b…
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Long-Term Blood Pressure Control Effect of Celiac Plexus Block with Botulinum Toxin.
Celiac plexus block (CPB) is one of the main treatment options for patients resistant to conventional antihypertensive drugs. We present a case of resistant hypertension (RHTN) that was treated with CPB using botulinum toxin. An 18-year-old…
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Feasibility of robot-assisted modified radical neck dissection by post-auricular facelift approach.
The aim of this study was to evaluate the technical feasibility and safety of robot-assisted modified radical neck dissection (MRND) for head and neck cancer patients with a clinically node-positive neck. The cases of 10 head and neck cance…
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Acute suppression of TGF-ß with local, sustained release of tranilast against the formation of fibrous capsules around silicone implants.
We propose the acute, local suppression of transforming growth factor beta (TGF-ß), a major profibrotic cytokine, to reduce fibrosis around silicone implants. To this end, we prepared silicone implants that were able to release tranilast, a…