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Role of HGF in epithelial-stromal cell interactions during progression from benign breast disease to ductal carcinoma in situ.
[INTRODUCTION] Basal-like and luminal breast cancers have distinct stromal-epithelial interactions, which play a role in progression to invasive cancer. However, little is known about how stromal-epithelial interactions evolve in benign and…
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Age-associated gene expression in normal breast tissue mirrors qualitative age-at-incidence patterns for breast cancer.
[BACKGROUND] Age is the strongest breast cancer risk factor, with overall breast cancer risk increasing steadily beginning at approximately 30 years of age. However, while breast cancer risk is lower among younger women, young women's breas…