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209건 · 최신순-
Repair of facial scars using free and pedicle-expanded deltopectoral flaps.
This study aimed to evaluate the effectiveness and long-term outcomes of free and pedicled, expanded deltopectoral flaps with perforation of the internal thoracic artery to repair facial scars. This retrospective review was of 37 patients w…
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Reconstruction of parotid duct defect with autologous vein graft and vascular coupler after buccal mucosa cancer resection.
The distal end of parotid duct is often inevitably resected en-block with the buccal mucosa cancer to obtain safety margin and prevent local recurrence. Ligation of duct frequently causes complications like cheek swelling, fistula and gland…
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Cavernous malformations of the hypothalamus: a single-institution series of 12 cases and review of the literature.
[OBJECTIVE] There remains a paucity of literature on hypothalamic cavernous malformations (HCMs). Here, the authors present the largest series of HCMs to date and review the literature to gain additional insight into this rare disease subse…
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An alternative therapeutic strategy for infected large bone defect and massive soft-tissue loss of leg-is free flap reconstruction inevitable?
[PURPOSE] This study aims to report the clinical and radiographic outcomes of a non-flap therapeutic strategy for the limb salvage of infected composite bone and soft-tissue defects of a leg, attempting to describe some new techniques regar…
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The use of botulinum toxin A in upper lip augmentation.
[BACKGROUND] Full lips are beauty standards. Botulinum toxin A (BTA) paralyzes the orbicularis oris muscle to achieve the eversion of the lip, and thus makes the lip look plump. [AIMS] This study presents three cases of BTA injection to th…
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Rac1/Wave2/Arp3 Pathway Mediates Rat Blood-Brain Barrier Dysfunction under Simulated Microgravity Based on Proteomics Strategy.
The blood-brain barrier (BBB) is critical to maintaining central nervous system (CNS) homeostasis. However, the effects of microgravity (MG) on the BBB remain unclear. This study aimed to investigate the influence of simulated MG (SMG) on t…
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The safety and efficacy of intralesional triamcinolone acetonide for keloids and hypertrophic scars: A systematic review and meta-analysis.
[BACKGROUND] Triamcinolone acetonide (TAC) is widely used for hypertrophic scars and keloids; however, TAC has variable efficacy and safety in different individuals. [PURPOSE] To evaluate the efficacy and safety of intralesional TAC for tr…
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The safety and efficacy of botulinum toxin A on the treatment of depression.
[OBJECTIVES] Effective strategy for the treatment of depression is limited. This study was to evaluate the safety and efficacy of botulinum toxin A (BoNT/A) in the treatment of depression. [METHODS] Seventy-six patients were assigned to th…
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Botulinum toxin type a intralesional monotherapy for treating human hypertrophic scar in a dose-dependent manner: In an animal model.
[BACKGROUND] The effect of Botulinum toxin type A (BTX-A) in treating or preventing a hypertrophic scar (HS) had been reported in clinical studies. However, the dose-effect relationship remains unclear. [OBJECTIVE] To study the dose-effect…
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A Reliable Method for Chin Augmentation by Mechanical Micronization of Lipoaspirates.
[BACKGROUND] Desire for improved aesthetic contour of the lower third of the face has resulted in an increase in chin augmentation. Although many fillers, including hyaluronic acid (HA), autologous fat and stromal vascular fraction gel (SVF…
- Correction to: A Reliable Method for Chin Augmentation by Mechanical Micronization of Lipoaspirates.
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A New Method of Correcting Cryptotia by Changing Mechanical Fulcrum After Constricted Cartilage Overturned.
[BACKGROUND] Many techniques have been introduced to correct cryptotia. The previous methods are releasing the constricted cartilage and changing the mechanical fulcrum partly to the right position. However, some patients are still not sati…
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Application analysis of a modified retroauricular hairline incision in the resection of a benign parotid gland tumor.
[OBJECTIVES] This study aimed to evaluate the application value of a modified retroauricular hairline incision and a sternocleidomastoid flap with an inferior pedicle in the resection of benign parotid gland tumors. [METHODS] Forty-eight p…
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[The ocular plastic surgery market should be regulated].
With the vigorous development of the market economy and the continuous improvement of people's living standards, the pursuit of beauty has grown correspondingly. Among the plastic surgeries, ocular plastic surgery is the most popular one, a…
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Prepectoral Versus Subpectoral Implant-Based Breast Reconstruction: A Meta-analysis.
[BACKGROUND] There is currently no consensus on the ideal plane for implant placement in breast reconstruction. The study compares the clinical efficacy and safety between prepectoral and subpectoral implant-based breast reconstruction. [M…
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Aging-associated sinus arrest and sick sinus syndrome in adult zebrafish.
Because of its powerful genetics, the adult zebrafish has been increasingly used for studying cardiovascular diseases. Considering its heart rate of ~100 beats per minute at ambient temperature, which is very close to human, we assessed the…
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Nerve root entrapment with pseudomeningocele after percutaneous endoscopic lumbar discectomy: A case report.
Pseudomeningocele is a relatively uncommon postoperative complication of spine surgery. Although the condition tends to be asymptomatic and self-limiting, it may cause radicular pain and neurological defect due to herniation of the nerve ro…
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Comparison of hand-sewn versus modified coupled arterial anastomoses in head and neck reconstruction: a single operator's experience.
Microvascular coupler devices have gained wide acceptance as an alternative to the traditional hand-sewn technique in reconstructive surgery. However, no study has directly compared the efficacy of the coupler and hand-sewn techniques in ar…
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Cosmetic and functional results of a newly reconstructed thumb by combining the phalanx of second toe and the great toenail flap transplantation.
[BACKGROUND] Microsurgical toe-to-hand transfer is a gold standard when it comes to repairing a thumb defect. Great toenail flap, thumbnail valva flap, free great toe, and second toe transplantation are the common methods in thumb reconstru…
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Research trends and performances of breast reconstruction: a bibliometric analysis.
[BACKGROUND] The need for postmastectomy breast reconstruction surgery has increased dramatically, and significant progress has been made both in implant and autologous based breast reconstruction in recent decades. In this paper, we perfor…
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Local Injection of Botulinum Toxin Type A to Prevent Postoperative Scar.
[BACKGROUND] Physical scars, especially those in the head and neck area, can cause emotional and psychological distress. Recent studies, have suggested that botulinum toxin type A (BTX-A), also known as Botox, may improve surgical scars by …
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Inhibition of chemotherapy-related breast tumor EMT by application of redox-sensitive siRNA delivery system CSO-ss-SA/siRNA along with doxorubicin treatment.
Metastasis is one of the main reasons causing death in cancer patients. It was reported that chemotherapy might induce metastasis. In order to uncover the mechanism of chemotherapy-induced metastasis and find solutions to inhibit treatment-…
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Botulinum Toxin A Improves Supramuscular Fat Graft Retention by Enhancing Angiogenesis and Adipogenesis.
[BACKGROUND] Autologous fat grafting is commonly used for soft-tissue augmentation and reconstruction in plastic surgery. However, long-term graft retention rates are unpredictable, especially in muscle-related fat grafting. [OBJECTIVE] To…
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Inhibition of Rac1 reverses enzalutamide resistance in castration-resistant prostate cancer.
Enzalutamide, an androgen receptor inhibitor, has been clinically approved for the treatment of metastatic castration-resistant prostate cancer (CRPC) in the United States. However, patients only benefit from enzalutamide for a short period…
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Stress-Sensitive Protein Rac1 and Its Involvement in Neurodevelopmental Disorders.
Ras-related C3 botulinum toxin substrate 1 (Rac1) is a small GTPase that is well known for its sensitivity to the environmental stress of a cell or an organism. It senses the external signals which are transmitted from membrane-bound recept…
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Efficacy and Safety of Botulinum Toxin vs. Placebo in Depression: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
Major depressive disorder (MDD) is a serious mental disorder that represents a substantial public health problem. Several trials have been undertaken to investigate the role of botulinum toxin type A (BTX-A) in the treatment of MDD, but the…
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Transcriptome analysis and functional identification of adipose-derived mesenchymal stem cells in secondary lymphedema.
[BACKGROUND] Secondary lymphedema is a common condition that affects patients with malignant tumors. Conservative treatments fail to provide lasting relief because they do not address the underlying pathological accumulation of excessive fa…
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The effects of macrophage-mediated inflammatory response to the donor site on long-term retention of a fat graft in the recipient site in a mice model.
Inflammatory responses mediated by macrophages play a role in tissue repair. However, it is unclear whether the repair in the donor site after liposuction would have any effects on fat graft retention in the recipient site. This study is de…
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Necrotizing fasciitis complicated with multiple organ dysfunction syndrome after breast augmentation with fat from the waist and lower extremities: a case report.
Necrotizing fasciitis (NF) is a rapidly progressing soft tissue infection with a mortality rate as high as 30% to 50%. However, the incidence rate of NF after liposuction is extremely low. In the current case report, we describe a woman wit…
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Equity of access to post-mastectomy breast reconstruction at a regional plastic surgery centre.
[BACKGROUND] The Plastic and Reconstructive Surgery Department at the Counties Manukau District Health Board provides tertiary-level access to post-mastectomy breast reconstruction for all women in the northern region of New Zealand. Access…