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96건 · 최신순-
Allogeneic Whole Eye Transplantation in Macaques Achieves 19-Day Graft Survival With Structural and Functional Viability.
[PURPOSE] Whole eye transplantation (WET) is a promising approach for vision restoration in severe ocular damage. This study pioneers an allogeneic whole-eye transplantation model in non-human primates, designed to: (1) Establish standardiz…
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Retrospective cohort study of ocular adverse reactions to systemic drugs: insights from a multi-country spontaneous reporting database.
[BACKGROUND] With the rise in long-term medication use, assessing ocular adverse reactions (OARs) from systemic drugs has gained importance. Using large real-world databases like the FDA Adverse Event Reporting System (FAERS) offers valuabl…
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Cryo-EM Structure Guided Engineering of Botulinum Neurotoxin A With Advanced Receptor Binding Affinity and Therapeutical Benefits.
Botulinum neurotoxin type A (BoNT/A) has been extensively used in treating a wide range of neurological disorders and aesthetics. However, insufficient binding affinity between BoNT/A and its receptor SV2C could lead to mild to severe side …
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Dynamic Eyelid Evaluation Using a Deep Neural Network in Upper Blepharoplasty: A Prospective Multicenter Pilot Study.
[BACKGROUND] Upper blepharoplasty is the most common cosmetic procedure in East Asia. A natural Asian double eyelid features specific crease characteristics. AI advancements, such as UNet and PointRend, enhance medical image segmentation, a…
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Contrast-enhanced Ultrasound for Assessing Pre-operative Lymphatic Vessel Function and Post-operative Anastomotic Patency in Lymphatic-venous Anastomosis: A Retrospective Observational Study.
[RATIONALE AND OBJECTIVES] Lymphedema represents a significant global health challenge, severely impacting patient quality of life. Lymphatic-venous Anastomosis （LVA） is commonly employed as an effective intervention for patients with lymph…
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A novel T-shaped incision of the tunica vaginalis for managing adhesions during vasoepididymostomy.
[PURPOSE] To propose a novel surgical approach for managing inflammatory adhesions of the tunica vaginalis (TV) during vasoepididymostomy (VE), and to report surgical outcomes. [MATERIALS AND METHODS] A T-shaped incision of the TV was used…
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Development and Validation of a Nomogram Incorporating Changes in Inflammatory Markers for Predicting Complications After Free Flap Reconstruction of Oral and Maxillofacial Defects.
[OBJECTIVE] To investigate the associations between inflammatory markers changes before and after free flap reconstruction and postoperative complications, and to develop and validate a nomogram with perioperative inflammatory markers chang…
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Developing a predictive nomogram model for incidence of adverse outcomes in oral and maxillofacial tumor patients undergoing free flap reconstruction.
[BACKGROUND] Surgical treatment of oral and maxillofacial tumors is complex, and the factors contributing to adverse outcomes remain incompletely understood. This study aimed to identify independent risk factors and develop an efficient nom…
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Circumferential periareolar incision length as a risk factor for skin necrosis after nipple-sparing mastectomy with deep inferior epigastric perforator flap reconstruction.
[BACKGROUND] Nipple-sparing mastectomy (NSM) with autologous tissue reconstruction offers excellent cosmetic outcomes but can be complicated by skin necrosis. This study aimed to investigate the risk factors for skin necrosis after NSM with…
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Impact of postoperative complications on patient-reported outcomes in deep inferior epigastric perforator flap breast reconstruction.
[OBJECTIVE] This study aims to investigate the factors that influence the occurrence of complications following deep inferior epigastric perforator (DIEP) flap breast reconstruction, and to determine whether these complications have an impa…
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VYC-25L Is Safe and Effective for Enhancing the Chin and Jawline by Correcting Chin Retrusion in Chinese Adults.
[BACKGROUND] Individuals with chin retrusion may seek chin and lower jawline aesthetic enhancement. [OBJECTIVES] To evaluate VYC-25L (Juvéderm Volux XC; Allergan Aesthetics, an AbbVie company), a lidocaine-containing injectable hyaluronic …
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The Efficacy and Safety of Botulinum Toxin Type A in Prevention of Hypertrophic Scars After Epicanthoplasty: A Split-Face Double-Blinded Randomized Controlled Trial.
[BACKGROUND] Timely intervention can improve the aesthetic outcome of surgical scars, and botulinum toxin type A (BTXA) has demonstrated its potential as an effective treatment. However, conclusive scientific evidence is needed to definitiv…
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Prevention strategies of esophageal stenosis after endoscopic resection for superficial esophageal cancer: a Bayesian network meta-analysis.
[INTRODUCTION] What interventions effectively prevent postoperative stenosis following endoscopic resection (ER) of superficial esophageal cancer? This study aimed to identify effective interventions or combinations through a systematic rev…
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Comparison of the Effects of Botulinum Toxin A Injection and Local Glucocorticoid Injection for Treating Laryngeal Contact Granuloma.
[OBJECTIVES] To compare the effects of botulinum toxin A injection and local glucocorticoid injection for treating laryngeal contact granuloma and to discuss the indications for both regimens. [METHODS] The case data of 50 patients with la…
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TNFAIP8L2 maintains hair cell function and regulates age-related hearing loss via mTORC1 signaling.
Age-related hearing loss (ARHL) is one of the most prevalent and complex disorders. Our previous study demonstrated that abnormal activation of mammalian target of rapamycin complex 1 (mTORC1) signaling in the cochlear neurosensory epitheli…
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Follicular Unit Excision Hair Removal of Unwanted Facial Terminal Hair in Five Facial Areas: A Retrospective Multicenter Cohort Study.
[BACKGROUND] Conventional epilation methods commonly encounter challenges in achieving permanent removal of unwanted facial terminal hair (uFTH), particularly when it is interspersed among normal hairs. [OBJECTIVE] To assess the safety and…
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Treatment outcomes in lower limb lymphedema misdiagnosed as iliac vein compression syndrome: A retrospective analysis.
Iliac vein compression is highly prevalent in the general population, which may lead to misdiagnosis of lower limb lymphedema as iliac vein compression syndrome and subsequent stent placement. This study retrospectively analyzed the treatme…
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Single-cell RNA sequencing reveals prolonged polyacrylamide hydrogel stimulation in vivo leads to an immunosuppressive microenvironment and potential tumorigenesis.
[BACKGROUND] Polyacrylamide hydrogel (PAAG) was once a prevalent filler for augmentation surgery. It was banned in China in 2006 due to persistent adverse reactions. However, numerous patients who received PAAG injection still suffer from P…
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Correction of upper eyelid retraction following ptosis surgery using Hering's law: A case report.
[RATIONALE] Blepharoptosis is a common disorder characterized by abnormal eyelid position that affects both visual function and esthetics. Postoperative upper eyelid retraction, which is often due to overcorrection, is a major problem. Unde…
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A Bibliometric Review of Software Tools in Plastic Surgery: How They Benefit Surgeons and Improve Practice from 2004 to 2024.
[BACKGROUND] Bibliometric analyses of software applications in plastic surgery are relatively limited. This study aims to address this gap by summarizing current research trends and providing insights that may guide future developments in t…
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Exploring the Prevalence and Etiological Factors of Body Dysmorphic Disorder in Cosmetic Surgery Populations: Implications for Enhanced Clinical Assessment.
[BACKGROUND] The prevalence of body dysmorphic disorder (BDD) varies across different clinical settings, with evidence indicating its notable presence not only in psychiatric environments but also in dermatology and plastic surgery. This ar…
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[Preclinical Physicochemical Evaluation of Injectable Fillers for Plastic Surgery].
Injectable fillers for plastic surgery are widely used in the field of aesthetic plastic surgery, and their safety and effectiveness are of vital importance. To ensure the safety and effectiveness of the products, it is indispensable to con…
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Untethered Microgrippers for Precision Medicine.
Microgrippers, a branch of micro/nanorobots, refer to motile miniaturized machines that are of a size in the range of several to hundreds of micrometers. Compared with tethered grippers or other microscopic diagnostic and surgical equipment…
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Development and validation of a novel nomogram model for identifying risk of prolonged length of stay among patients receiving free vascularized flap reconstruction of head and neck cancer.
[BACKGROUND] The aim of the present study was to build and internally validate a nomogram model for predicting prolonged length of stay (PLOS) among patients receiving free vascularized flap reconstruction of head and neck cancer (HNC). [M…
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Comparison of local excision and total mesorectal excision for rectal cancer: Systematic review and meta-analysis of randomised controlled trial.
To report the first and largest systematic review and meta-analysis of radomised controlled trials (RCTs) to compare the efficacy and safety of transanal endoscopic microsurgery (TEM) and total mesorectal excision (TME) for rectal cancer fo…
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Intraoperative circulation predict prolonged length of stay after head and neck free flap reconstruction: a retrospective study based on machine learning.
[BACKGROUND] Head and neck free flap reconstruction presents challenges in managing intraoperative circulation, potentially leading to prolonged length of stay (PLOS). Limited research exists on the associations between intraoperative circu…
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Transdermal delivery of botulinum toxin-A through phosphatidylcholine/cholesterol nanoliposomes for treatment of post-acne scarring.
As an acne sequela, post-acne scarring (PSA) has huge negative impact on sufferers' quality of life because of aesthetical embarrassment. Transdermal delivery of botulinum toxin-A (BTXA) is a promising strategy for PAS treatment, but curren…
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[Analysis of the efficacy of vocal cord botulinum toxin injection for refractory laryngeal contact granuloma].
To observe the efficacy of vocal cord botulinum toxin type A injection in the treatment of refractory laryngeal contact granuloma and to analyze the factors affecting the curative effect. Fifty-two patients with refractory laryngeal contac…
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Vulvar migration of injected polyacrylamide hydrogel following breast augmentation: a case report and literature review.
[BACKGROUND] Vulvar migration is a rare complication of filler injection for breast augmentation, generally presenting as repeated pain and fever. We will report a case of woman with polyacrylamide hydrogel breast injection develops vulvar …
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Surgical Correction of Depressed Scars After Upper Blepharoplasty: A Turnover Orbicularis-Septum Composite Flap Technique.
[OBJECTIVE] Depressed scarring is a common complication after incisional upper blepharoplasty and frequently contributes to patient dissatisfaction. Correcting this deformity presents a significant challenge for oculoplastic surgeons. This …