논문 목록
16건-
Case report: ectopic papillary thyroid carcinoma found in the midline of the hyoid bone and cervical lymph nodes, no thyroid lesions.
[BACKGROUND] Ectopic thyroid tissue (ETT) is primarily caused by embryonic dysplasia. It is commonly located laterally in the neck or in the thyroglossal duct, as well as in more remote locations like the mediastinum and the subdiaphragmati…
- Disease status stratification individualizes radioiodine therapy for differentiated thyroid cancer: a prospective, multicenter, real-world study.
- Beyond the QoR-15K: addressing clinical nuances and fasting-related symptom burden in gastric cancer ERAS.
-
Cardiotoxicity associated with antineoplastic agents: a pharmacovigilance study based on FDA adverse event reporting system.
[BACKGROUND] Cardiovascular adverse events represent critical complications of antineoplastic therapy with profound implications for cancer survivorship and treatment outcomes. Despite the clinical significance, comprehensive pharmacovigila…
-
Thioketal-Incorporated Biodegradable Lipid Nanoparticles Deliver mRNA to Ductal Epithelial Cells for Improved Pancreatic Cancer Treatment.
Delivery of mRNA to the ductal epithelial cells remains a formidable challenge but holds substantial potential for pancreatic ductal adenocarcinoma (PDAC) treatment. Herein, for the first time, we report a new class of thioketal-incorporate…
-
Pancreatic dysfunction causally impacts region-specific cortical thinning: a mendelian randomization study revealing pancreas-brain axis.
[BACKGROUND] Alterations in cerebral cortex structure among patients with pancreatic diseases have been reported, yet the underlying causes remain unclear. This study employs Mendelian randomization (MR) to elucidate the causal effects of f…
-
WITHDRAWN: Evaluation of Circadian Rhythm-related Genes for Prognosis Modeling and Immune Characterization in Thyroid Cancer.
[UNLABELLED] The article has been withdrawn at the request of the authors. As a result, the publisher has withdrawn this article in accordance with ethical standards and best practices in scholarly publishing. Bentham Science apologizes to …
-
Uncovering Novel Susceptible Genes and Therapeutic Targets of Prostate Cancer: a Multi-omics Study Integrating Summary-based Mendelian Randomization Analysis and Molecular Docking.
[BACKGROUND] Understanding the role of causal genes of prostate cancer (PrCa) can reveal key biological pathways and identify potential targets for treatment. [METHODS] We investigated associations between genetically predicted gene expres…
-
DEPP1: A prognostic biomarker linked to stroma‑rich and immunosuppressive microenvironment, promoting oxaliplatin resistance in gastric cancer.
Decidual protein induced by progesterone (DEPP1) was identified to exert heterogeneous functions in several cancers, whereas its role in gastric cancer (GC) remains elusive. In the present study, differential expression analysis was conduct…
-
Long noncoding RNA MATN1-AS1 contributes to oxaliplatin resistance of gastric cancer cells through miR-518b/ZNF281 axis.
Chemoresistance leads to poor outcomes of patients with gastric cancer (GC). Long non-coding RNAs (lncRNAs) have been demonstrated as novel gene modulators in various carcinomas and chemoresistance. Our study aimed to investigate the role a…
-
Molecular mechanisms mediated by liquid-liquid phase separation in chronic liver disease progression.
Liquid-liquid phase separation (LLPS) is a cellular process driven by multivalent interactions, forming dynamic biomolecular condensates containing proteins, RNAs, and other molecules. LLPS plays a pivotal role in processes such as signal t…
-
Personalizing colorectal Cancer treatment: Chemotherapy drug testing with patient-derived tumor cell clusters.
[BACKGROUND] Due to the heterogeneity of colorectal cancer (CRC), models that can predict the chemotherapy response are needed to facilitate personalized treatment. [AIM] To construct patient-derived tumor-like cell cluster (PTC) models in…
-
A new treatment strategy for mid-low rectal cancer patients exhibiting a clinical complete or near-complete response to neoadjuvant chemoradiotherapy: Transanal endoscopic microsurgery --A multicenter prospective case-control clinical trial by MONT-R.
[BACKGROUND] Total mesorectal excision is the standard surgery for locally advanced rectal cancer (LARC) after neoadjuvant chemoradiotherapy (nCRT), but it may lead to high complication rates and poor quality of life. This study evaluates w…
-
Clinical characteristics and management for intracranial serpentine aneurysms: a 12-year single-center retrospective analysis of 51 patients.
[BACKGROUND] Serpentine aneurysms, a rare and complex type of intracranial aneurysm, pose significant treatment challenges. The natural course of these aneurysms and the definitive interventional treatment effect remains elusive. This study…
-
Diagnosis and Treatment of Acute Pleural Effusion following Radioiodine Remnant Ablation Post Lobectomy for Thyroid Cancer.
Radioiodine remnant ablation (RRA) was previously demonstrated to be a safe and effective alternative to completion thyroidectomy for patients with differentiated thyroid cancer (DTC). However, its side effects have not been fully investiga…
-
The Effectiveness and Safety of Botulinum Toxin Injections for the Treatment of Congenital Muscular Torticollis.
[OBJECTIVE] Botulinum toxin have been used to treat congenital muscular torticollis for the last 25 years; however, few studies have been published with only limited cases and short-term follow-up. The aim of the present study is to systema…