Rao P ⚠ 동명이인 가능성

Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) have transformed metabolic and aesthetic medicine, yet their potential influence on botulinum toxin type A (BoNT-A) pharmacodynamics remains unexplored. Using the AesthetiSIM™ microsimul…

Comparative evaluation of botulinum neurotoxin type A (BoNT/A) formulations is limited by short clinical trials and lack of long-term safety data. This study applied a validated multiscale computational model (AesthetiSIM™) to simulate 20 y…

Botulinum neurotoxin type A (BoNT/A) formulations differ mainly in excipients, which determine stability, aggregation, and diffusion. Using multi-scale in silico modelling (AesthetiSIM™), we evaluated excipient substitution across six marke…

[INTRODUCTION] Botulinum Neurotoxin type A (BoNT-A) formulations are used worldwide for both aesthetic and therapeutic indications, yet dose conversion between products remains based on empirical ratios that ignore pharmacodynamic variabili…

This study used a validated, literature anchored multiscale modelling platform (AesthetiSIM) to investigate whether common post injection behaviours influence the early distribution of botulinum toxin A (BoNT A). A cohort of 10,000 paired d…

[INTRODUCTION] Facial aging results from intrinsic biologic decline and extrinsic environmental influences, producing progressive changes in skin structure, collagen integrity, and soft-tissue support. Botulinum neurotoxin type A (BoNTA) is…

[BACKGROUND] Counterfeit Botulinum Toxin A (BoNT-A) poses a growing global threat, particularly in aesthetic medicine where regulatory oversight is minimal and underreporting is widespread. Traditional pharmacovigilance systems such as FAER…

Botulinum neurotoxin type A (BoNT/A) is a widely used biologic therapeutic, yet the influence of natural toxin sequence variation on the stability of neutralizing antibody binding remains poorly understood. In this study, we performed a com…

[BACKGROUND] Delayed inflammatory and fibrotic reactions to dermal fillers remain unpredictable, reflecting complex interactions between product composition and host genetics. [OBJECTIVE] To develop and validate a computational framework i…

[BACKGROUND] Botulinum toxin A (BoNT-A), derived from Clostridium botulinum , is widely used in medical and aesthetic treatments. Its clinical application extends from managing chronic conditions like cervical dystonia and migraine to reduc…

Botulinum toxin A (BoNT-A) is widely used in both therapeutic and aesthetic settings; however, the formation of neutralizing antibodies (NAbs) remains a critical concern, leading to treatment failure. Immunogenic responses are known to vary…

[INTRODUCTION] Aesthetic medicine has evolved towards minimally invasive procedures, with biostimulators like Poly-L-Lactic Acid (PLLA), Calcium Hydroxylapatite (CaHA), and Polycaprolactone (PCL) gaining attention for their role in collagen…

[INTRODUCTION] Non-surgical aesthetic treatments (NSATs) have gained significant traction over the past two decades, prized for their minimally invasive nature, cost-effectiveness, and rapid outcomes. Yet complications associated with these…

Anecdotal reports have recently circulated suggesting that intramuscular injection of bacteriostatic saline (BS)-which contains benzyl alcohol (BnOH)-can reverse botulinum toxin type A (BoNTA)-induced brow ptosis. Given the well-established…

While botulinum neurotoxin A (BoNT/A) is a cornerstone in glabellar wrinkle treatment, inconsistencies in clinical outcomes often stem from formulation-dependent diffusion behaviour. Currently volumes recommendation per site lacks mechanist…

[INTRODUCTION] Glabellar wrinkle patterns, a visible manifestation of facial dynamics and ageing, result from complex interactions between anatomical and functional variables such as muscle interdigitation density, skin elasticity, and subc…

[INTRODUCTION] The aesthetic medicine industry has seen significant growth due to technological advancements and increasing demand for minimally invasive procedures. This sector's influence on educational institutions is profound, often sha…

[BACKGROUND] The global aesthetic medicine industry is expanding rapidly, with conferences serving as crucial platforms for knowledge exchange and collaboration. However, concerns have emerged about the increasing prioritization of commerci…

[BACKGROUND] Botulinum toxin A (BTxA) has gained popularity as a nonsurgical aesthetic treatment for skin rejuvenation. However, previous studies on intradermal BTxA have shown inconsistent results. This systematic review and meta-analysis …

There is a need for a specialist pathway or progression in esthetic medicine for esthetic physicians. A structured program for specialized training in nonsurgical facial esthetics to empower physicians is the need of the hour. The pharmaceu…

[PURPOSE] This synaptic systemised review critically examines the provision of aesthetic medical care to LGBTQIA+ (lesbian, gay, bisexual, transgender, queer or questioning, intersex, asexual, and more) individuals, assessing both the clini…

The current consensus in the management of hypopharyngeal cancers favors the non-surgical management. However, many studies have reported relatively better oncological and functional outcomes with the surgical approach in locally advanced h…