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26건 · 최신순-
Botulinum Toxin Type A in the Treatment of Primary Axillary Hyperhidrosis:A Phase 3, Multicenter, Randomized, Double-Blind, Placebo-Controlled Study of Efficacy and Safety in Chinese Patients.
[BACKGROUND] The efficacy and safety of botulinum toxin type A (BoNTA) treatment for primary axillary hyperhidrosis (PAH) have not been explored in the Chinese population. [OBJECTIVES] The objective was to evaluate efficacy and safety of 1…
- Advancing aesthetic outcomes: a critical analysis of autologous free flap reconstruction post-minimally invasive mastectomy.
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A neonatal rat model of progressive left ventricular pressure overload induced by abdominal aortic banding microsurgery.
[OBJECTIVE] Left ventricular pressure overload models using adult mice or rats were developed 60 years ago; however, a neonatal mouse model of left ventricular pressure overload was reported only 5 years ago. Moreover, how left ventricular …
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Robot-assisted augmented reality navigation for osteotomy and personalized guide-plate in mandibular reconstruction: a preclinical study.
[BACKGROUND] Oral and maxillofacial tumors, particularly those requiring mandibular reconstruction, present significant clinical challenges due to the complexities involved in achieving precise surgical outcomes and ensuring post-operative …
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A 2-year retrospective study of endodontic microsurgery for bone fenestration.
[OBJECTIVES] To evaluate the clinical efficacy and relevant prognostic factors of endodontic microsurgery in cases with bone fenestration. [METHODS] The retrospective cohort study was conducted at the Endodontic Department of Hefei Stomato…
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Curcumin alleviates lipopolysaccharide-induced alveolar epithelial Glycocalyx damage by modulating the Rac1/NF-κB/HPSE pathway.
The glycocalyx, a cell surface component implicated in various diseases, has recently been recognized for its role in acute lung injury (ALI). Also known as the alveolar epithelial polysaccharide coat, it is vital for maintaining lung barri…
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Endodontic microsurgery and prosthodontic treatment of a permanent anterior concrescence: A case report.
Concrescence is a rare dental anomaly in which two adjacent teeth are united only by their cementum. Concrescence most frequently occurs in molars, especially a third mandibular molar and a supernumerary tooth. It is rarely seen in the maxi…
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Dynamic Repair Surgery for Late-Stage Facial Paralysis: Advances in Restoring Movement and Function.
Facial paralysis results from congenital or acquired facial nerve damage, leading to significant cosmetic and functional deficits. Surgical resection of parotid and midface tumors can cause facial paralysis, necessitating effective treatmen…
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Human Parathyroid Hormone (1-34) accelerates skin wound healing through inducing cell migration via up-regulating the expression of Rac1.
Delayed wound healing is a public issue that imposes a significant burden on both society and the patients themselves. To date, although numerous methods have been developed to accelerate the speed of wound closure, the therapeutic effects …
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Evaluation of safety, efficacy, and risk factors of different breast reconstruction strategies following polyacrylamide hydrogel removal: A 20-year retrospective cohort study of 436 cases.
[BACKGROUND] Globally implemented for breast augmentation, polyacrylamide hydrogel (PAAG) always leads to breast deformity upon its removal. Despite a pressing need for breast reconstruction following PAAG removal to address aesthetic issue…
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Modified individualized titanium mesh in orbital floor reconstruction for preventing exposure.
[OBJECTIVE] To describe a novel method of medial fixation of titanium mesh with a right-angled screwdriver for orbital floor and maxillary reconstruction and to compare the reconstruction outcome of orbital floor reconstruction with modifie…
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Application of a modified osteotomy and positioning integrative template system (MOPITS) based on a truncatable reconstruction model in the precise mandibular reconstruction with fibula free flap: a pilot clinical study.
[BACKGROUND] Mandibular defects can greatly affect patients' appearance and functionality. The preferred method to address this issue is reconstructive surgery using a fibular flap. The current personalized guide plate can improve the accur…
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Efficacy and Safety of AbobotulinumtoxinA for the Treatment of Glabellar Lines in Chinese Patients: A Pivotal, Phase 3, Randomized, Double-Blind and Open-Label Phase Study.
[BACKGROUND] Various botulinumtoxinA formulations are approved for glabellar lines treatment worldwide, including abobotulinumtoxinA (Dysport). [OBJECTIVES] Assess abobotulinumtoxinA superiority versus placebo and non-inferiority versus ac…
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Cryptotia Repair Using a Modified V-Y Advancement Flap with Helix Rounding Technique.
[BACKGROUND] Cryptotia is a common congenital auricular malformation seen in Asian people. To date, multiple surgical procedures have been described for correcting cryptotia. However, the deformity often recurs, presenting as an unclear aur…
- Delayed inflammatory reactions to hyaluronic acid filler injection: Should be treated but should not be overtreated.
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High-Frequency Ultrasound for Long-term Safety Assessment of Poly-L-Lactic Acid Facial Filler.
[BACKGROUND] Injectable poly- l -lactic acid (PLLA) is a new type of biodegradable dermal filler that has been utilized for soft tissue filling. However, there is no convenient and reliable method to assess the long-term safety of PLLA fill…
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Outcomes of combined pyloric botulinum toxin injection and balloon dilation in dyspepsia with and without delayed gastric emptying.
[BACKGROUND] Pyloric botulinum toxin injection has improved symptoms in children with delayed gastric emptying. We aimed to determine the clinical response to combined endoscopic intra-pyloric botulinum toxin injection and pyloric balloon d…
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The efficacy of botulinum toxin A in the treatment of Raynaud's phenomenon in systemic sclerosis: A randomized self-controlled trial.
The current conservative and surgical treatments are not fully effective and have complications for Raynaud's phenomenon (RP) secondary to systemic sclerosis (SSc). Botulinum toxin A (BTX-A) can be used to manage RP, but the literature most…
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Synthesis and activity evaluation of selenazole-coupled CPI-1 irreversible bifunctional inhibitors for botulinum toxin A light chain.
A series of novel conjugates of benzoselenazole or selenazole and CPI-1 were designed, synthesized, and evaluated for inhibitory activities against the botulinum neurotoxin A (BoNT/A) light chain (LC) and BoNT/A in vivo. The results show th…
- Botulinum Toxin A for the Treatment of Yellow Nail Syndrome and Palmar Primary Hyperhidrosis.
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Long-term Effect of Individualized Titanium Mesh in Orbital Floor Reconstruction After Maxillectomy.
[OBJECTIVE] The aim of this study was to determine the clinical outcomes and long-term stability of individualized titanium mesh combined with free flap for orbital floor reconstruction after maxillectomy and to identify the risk factors fo…
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Use of Botulinum Toxin in Treating Rosacea: A Systematic Review.
[BACKGROUND] Rosacea is a chronic skin disorder characterized by erythema, flushing, telangiectasia, papules and pustules, phymatous changes, and ocular involvement. The aim of this study was to examine all published research articles in wh…
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Botulinum toxin in treating Hailey-Hailey disease: A systematic review.
[BACKGROUND] Hailey-Hailey disease is a rare disorder characterized by recurrent painful blistering, erosions, maceration in the intertriginous regions. Botulinum toxin has been used in the treatment of Hailey-Hailey disease. [AIMS] This s…
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Chordoid Glioma of the Third Ventricle: A Case Report and a Treatment Strategy to This Rare Tumor.
Chordoid glioma (CG) of the third ventricle is a rare type of brain tumor. Here, we present a case, review of the literature and proposed a treatment strategy for this rare tumor. Here, A 33-years-old woman presented with the menstrual diso…
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Botulinum toxin as a double-edged sword in alopecia: A systematic review.
[BACKGROUND] Alopecia is a common disease influencing the quality of life of the patients. Botulinum toxin has been widely employed in cosmetic dermatology and was applied in some clinical trials to treat alopecia. [AIMS] Hence, We conduct…
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[Immediate breast and nipple reconstruction with the latissimus dorsi myocutaneous flap].
[OBJECTIVE] To investigate the feasibility of immediate breast and nipple-areola reconstruction after skin-sparing mastectomy. [METHODS] 24 patients who received skin-sparing mastectomy underwent immediate breast reconstruction with or wit…