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34건 · 최신순-
Microscopic ligation combined with shunt procedure versus microsurgical varicocelectomy for nutcracker syndrome and left varicocele: a randomized controlled trial.
[BACKGROUND] This study is to evaluate the safety and efficacy of a novel microsurgical approach (Microsurgical Spermatico-Inferior Epigastric Vein Anastomosis with Selective Venous Disconnection, MSEA-SVD) compared to conventional Microsur…
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Dermis-Orbicularis Oculi Muscle-Septoaponeurosis Junctional Thickening Fixation Technique for Double Eyelid Blepharoplasty.
[BACKGROUND] Full-incision double eyelid blepharoplasty is a widely sought-after procedure in East Asia. However, tarsus-skin or levator aponeurosis-skin fixation techniques may lead to deep folds and scarring. This study aimed to evaluate …
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Efficacy and Outcomes of Pedicled Upper Orbital Fat Fascia Flap Transposition Using 3D Facial Scanning: A Retrospective Study.
[BACKGROUND] Sunken upper eyelids convey an impression of fatigue. Pedicled orbital fat fascia flap (POFFF) transposition has been commonly adopted as an effective technique for augmenting upper eyelid volume. Nevertheless, objective quanti…
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Efficacy evaluation of the hard-channel technique and transsylvian microsurgical operation in the treatment of basal ganglia haemorrhage.
[OBJECTIVE] To compare the efficacy and safety of the hard-channel technique and the transsylvian microsurgical operation in treating basal ganglia cerebral haemorrhage (BGCH). [METHODS] Clinical data from 100 patients with BGCH treated at…
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Recombinant Detoxified Holotoxin as a Potent Candidate Vaccine Against Botulism.
Vaccination may represent a suitable strategy for preventing botulism. The recombinant expression of toxin functional domains can induce effective immune responses against botulism. This study aims to develop a safe and effective recombinan…
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A Prospective and Comparative Study to Explore the Effects of Platelet-Rich Plasma in Hair Transplantation for Patients With Androgenetic Alopecia.
[BACKGROUND] Androgenetic alopecia (AGA) is the most prevalent type of hair loss. Traditionally, treatment for AGA has primarily involved the topical application of minoxidil in conjunction with oral finasteride or spironolactone. Recently,…
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Nonsurgical Approach to Treat Post-Rhinoplasty Vascular Complication With Hyaluronic Acid Injection.
[BACKGROUND] Hyaluronic acid (HA) fillers are popular for their minimally invasive nature and immediate aesthetic outcomes, but vascular compromise remains a significant complication. This study investigates optimized therapeutic strategies…
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An Analysis of Severe Ophthalmologic Complications Following Plastic and Cosmetic Procedures: Insights and Experience Sharing.
[BACKGROUNDS] Although severe ocular complications following plastic and cosmetic surgeries or treatments are relatively uncommon, early diagnosis and intervention are essential for improving prognosis. This study investigates optimized str…
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Transcutaneous oxygen tension-guided hyperbaric oxygen therapy for preventing skin necrosis after hyaluronic acid filler injections.
[INTRODUCTION] Hyaluronic acid (HA) fillers, popular for facial cosmetic enhancements, pose risks of vascular complications like skin necrosis due to arterial blockage, necessitating effective treatments such as hyperbaric oxygen therapy (H…
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Treating rosacea with botulism toxin: Protocol for a systematic review and meta-analysis.
[BACKGROUND] Rosacea is a chronic inflammatory disease usually associated with persistent erythema and periodic flushing. This disease is difficult to treat, and the outcomes are often unsatisfactory and prone to recurrence. In recent years…
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Complications of Injected Exogenous Growth Factor for Cosmetic Facial Rejuvenation: A Case Series and Sequential Therapy.
[BACKGROUND] Exogenous growth factor presents promising soft tissue regeneration, but the complications from injectable exogenous growth factor seem to be growing. However, there is no detailed summary of complications and sequential treatm…
- A comparison of autologous auricular cartilage transplantation and prosthetic material transplantation of rhinoplasty patients.
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Open thoracic surgical implantation of cardiac pacemakers in rats.
Genetic engineering and implantable bioelectronics have transformed investigations of cardiovascular physiology and disease. However, the two approaches have been difficult to combine in the same species: genetic engineering is applied prim…
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Intramuscular Microvascular Flow Sensing for Flap Monitoring in a Porcine Model of Arterial and Venous Occlusion.
[BACKGROUND] Commercially available near infrared spectroscopy devices for continuous free flap tissue oxygenation (StO) monitoring can only be used on flaps with a cutaneous component. Additionally, differences in skin quality and pigment…
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Combination of High Ligation and Intraoperative Embolization Using Polidocanol for Treatment of Varicoceles.
Varicoceles are dilated veins within the pampiniform plexus and are relatively common in the general male population. The spermatic vein has many branches in the scrotal segment and then gradually merges into 1-2 trunks after passing throug…
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Klotho inhibits renal ox-LDL deposition via IGF-1R/RAC1/OLR1 signaling to ameliorate podocyte injury in diabetic kidney disease.
[OBJECTIVE] Diabetic kidney disease (DKD) is characterized by the abnormal deposition of oxidized low-density lipoprotein (ox-LDL), which contributes to podocyte damage. Klotho, an aging suppressor that plays a critical role in protecting p…
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Intramuscular Near-Infrared Spectroscopy for Muscle Flap Monitoring in a Porcine Model.
[BACKGROUND] Current near-infrared spectroscopy (NIRS)-based systems for continuous flap monitoring are limited to flaps which carry a cutaneous paddle. As such, this useful and reliable technology has not previously been applicable to mus…
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Implantable, wireless, self-fixing thermal sensors for continuous measurements of microvascular blood flow in flaps and organ grafts.
Vascular pedicle thrombosis after free flap transfer or solid organ transplantation surgeries can lead to flap necrosis, organ loss requiring re-transplantation, or even death. Although implantable flow sensors can provide early warning of …
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Combined Immunodeficiency Caused by a Novel De Novo Gain-of-Function RAC2 Mutation.
Ras-related C3 botulinum toxin substrate 2 (RAC2) is a GTPase exclusively expressed in hematopoietic cells that acts as a pivotal regulator of several aspects of cell behavior via various cellular processes. RAC2 undergoes a tightly regulat…
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A multifunctional substance P-conjugated chitosan hydrochloride hydrogel accelerates full-thickness wound healing by enhancing synchronized vascularization, extracellular matrix deposition, and nerve regeneration.
Due to the native skin limitations and the complexity of reconstructive microsurgery, advanced biomaterials are urgently required to promote wound healing for severe skin defects caused by accidents and disasters. Accumulating evidence has …
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The Impact of Prior Abdominal Surgery on Complications of Abdominally Based Autologous Breast Reconstruction: A Systematic Review and Meta-Analysis.
[BACKGROUND] Approximately half of all patients presenting for autologous breast reconstruction have abdominal scars from prior surgery, the presence of which is considered by some a relative contraindication for abdominally based reconstr…
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Evaluation of respiratory system anomalies associated with microtia in a Chinese specialty clinic population.
[BACKGROUND] Microtia is a congenital malformation of the external ear often with one or more associated congenital anomalies. The purpose of this study was to identify the characteristics and prevalence of respiratory anomalies in patients…
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Microsurgical gonadal-inferior epigastric vein anastomosis to treat the nutcracker phenomenon with left gonadal vein varices with reflux.
[OBJECTIVE] To evaluate the effectiveness and safety of microsurgical gonadal-inferior epigastric vein anastomosis for the treatment of the nutcracker phenomenon (NCP) associated with left gonadal vein varices with reflux. [METHODS] Thirty…
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Physiological correction of mild to moderate congenital blepharoptosis: A retrospective cohort study involving 97 Eastern Asian patients.
[BACKGROUND] Conventional blepharoptosis repair methods distort the normal anatomy of levator aponeurosis and often cause a visible depressed scar in the upper eyelid. [METHODS] The levator aponeurosis was dissected as a flap from the pret…
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Complications and Treatment Strategy After Breast Augmentation by Polyacrylamide Hydrogel Injection: Summary of 10-Year Clinical Experience.
From 1997 to 2006, polyacrylamide hydrogel (PAAG) was approved for use in China as a permanent filler for breast augmentation, and it is estimated that 200,000 women have undergone PAAG injection since then. After injection, complications s…
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Surgical correction of cryptotia combined with an ultra-delicate split-thickness skin graft in continuity with a full-thickness skin rotation flap.
[BACKGROUND] Cryptotia is a common congenital ear deformity in Asian populations. In cryptotia, a portion of the upper ear is hidden and fixed in a pocket of the skin of the mastoid. Here we describe our method for cryptotia correction by u…
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p53 alteration in morphologically normal/benign breast luminal cells in BRCA carriers with or without history of breast cancer.
Germline mutations in BRCA genes have been shown to predispose patients to breast cancer. Studies have suggested that p53 alteration is a necessary step in tumorigenesis in BRCA carriers. Our previous study showed p53 alteration in morpholo…
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Clinical Assessment of the Safety and Effectiveness of Nonablative Fractional Laser Combined with Transdermal Delivery of Botulinum Toxin A in Treating Periocular Wrinkles.
The upper and lower eyelids are traditionally contraindicated for subcutaneous botulinum toxin A (BTX) injection because of possible complications. We assessed the clinical safety and effectiveness of nonablative fractional laser (NAFL) com…
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p53 alteration in morphologically normal/benign breast tissue in patients with triple-negative high-grade breast carcinomas: breast p53 signature?
p53 alterations have been identified in approximately 23% of breast carcinomas, particularly in hormone receptor-negative high-grade carcinomas. It is considered to be an early event in breast carcinogenesis. Nevertheless, the putative prec…
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Three-dimensional autologous cartilage framework fabrication assisted by new additive manufactured ear-shaped templates for microtia reconstruction.
[BACKGROUND] During microtia reconstruction, the intraoperative design of the cartilage framework is important for the appearance and symmetry of the bilateral auricles. Templates (traditionally, the X-ray film template) are usually utilize…