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81건 · 최신순-
Soft Micromanipulation Robot for Real-Time Adaptive Multimodal Operation.
Micromanipulation robots hold immense promise for biomedical applications, yet they remain fundamentally limited by three persistent challenges: cross-scale target heterogeneity, spatially constrained workspaces, and integrated multimodal o…
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Is the use of intraoperative vasopressors associated with flap failure in head and neck free tissue transfer surgery?
[BACKGROUND] Maintaining appropriate blood pressure during head and neck free tissue transfer surgery is important for both organ and flap perfusion. However, the use of vasopressors to treat intraoperative hypotension is controversial. The…
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A Novel Robot-Assisted Access in Endodontic Microsurgery Combined with Sinus Floor Elevation for Maxillary First Molar.
Endodontic microsurgery (EMS) is an important treatment option for endodontic disease when the nonsurgical endodontic treatment fails. However, EMS for maxillary molars often presents a clinical challenge due to the root apex close to the m…
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Spiky Nanoparticle-Gel Composite for Efficient Intravesical Botulinum Toxin A Delivery and Treatment of Overactive Bladder.
Overactive bladder (OAB) is a symptomatic disease that is difficult to treat. This study developed APTES-functionalized spiky titanium dioxide nanoparticles (ASNPs) loaded with botulinum toxin A (ASNP@BA), which is coated with P407/HA (HP) …
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Rac1 promotes exosome secretion from proximal renal tubules to accelerate DKD.
Chronic low-grade sterile inflammation is one hallmark of diabetic kidney disease (DKD). Exosomes secretion from renal cells plays an important role in the transmission of inflammatory substances, which is associated with DKD. Ras-related C…
- The Nerve Block Advance in Blepharoplasty: A Call for Rigorous Validation.
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A web-based predictive model for secondary skin infections in breast cancer patients undergoing reconstruction.
[BACKGROUND] Breast cancer (BC) is one of the most common malignancies in women worldwide, with surgical interventions such as mastectomy and implant-based reconstruction playing a key role in management. While implant-based reconstruction …
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Prepectoral versus Subpectoral Dual-Plane Direct-to-Implant Breast Reconstruction with the TiLoop Bra: A Single-Center Prospective Cohort Study.
[BACKGROUND] Advancements in surgical techniques and materials have increased the use of direct-to-implant breast reconstruction after mastectomy. However, the optimal implant placement remains debated, with limited prospective studies comp…
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Microsurgical outcomes for vestibular schwannomas associated with trigeminal neuralgia.
Trigeminal neuralgia (TN) is a disorder characterized by recurrent, severe, brief pain in the distribution of the trigeminal nerve. Secondary TN may be caused by tumors in the cerebellopontine angle (CPA), including vestibular schwannomas (…
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Innovative dura-splitting strategy for resection of spinal meningioma along with the inner layer of dura mater.
[OBJECTIVE] Spinal meningioma is a common extramedullary tumor that can theoretically be cured by complete microsurgical resection. However, complete resection of the tumor is challenging with traditional surgical strategies due to the vari…
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Application of the Knotting After Half-side Threaded Anastomosis Method in Free Anterolateral Thigh Flap Repair.
[PURPOSE] The anterolateral thigh (ALT) flap serves as a pivotal technique for maxillofacial defect restoration. The prognosis of free flap repair is critically tied to the quality of vascular anastomosis. In this study, we introduced the K…
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Surgical outcomes in elderly patients with vestibular schwannoma: a retrospective cohort study.
This study aims to evaluate the surgical outcomes and clinical differences of elderly vestibular schwannoma (VS) patients (> 65 years), compared with non-elderly patients, focusing on baseline characteristics, preoperative symptoms, postope…
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Long-Term Nervus Intermedius Function Outcomes and Their Predictors in Patients With Vestibular Schwannoma After Microsurgery.
[BACKGROUND AND OBJECTIVES] The aim of this retrospective study was to identify predictors of long-term dysfunction of the nervus intermedius (NI) after vestibular schwannoma (VS) surgery. [METHODS] A follow-up questionnaire was administer…
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Analysis of Research Waste in Phase III/IV Randomized Controlled Trials of Botulinum Toxin Type A.
[BACKGROUND] The application of randomized controlled trials (RCTs) outcomes of botulinum toxin type A (BoNT-A) to actual patient care faces a significant hurdle due to research waste (RW). This includes the results of RCTs that have not be…
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Advancements in the management of overactive bladder in women using nano-botulinum toxin type A: A narrative review.
Intravesical injections of botulinum toxin type A (BTX-A) are effective for treating refractory overactive bladder (OAB) in women. However, the adverse effects linked to the injections, such as hematuria, pain, and infection, and need for r…
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Vertical inhibition of p110α/AKT and N-cadherin enhances treatment efficacy in PIK3CA-aberrated ovarian cancer cells.
Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha [PIK3CA, encoding PI3Kalpha (also known as p110α)] is one of the most commonly aberrated genes in human cancers. In serous ovarian cancer, PIK3CA amplification is highly…
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Safety and efficacy of intravesical instillation of botulinum toxin-A in the treatment of interstitial cystitis/bladder pain syndrome and overactive bladder: a systematic review and meta-analysis.
[BACKGROUND] The effectiveness and safety of the instillation of botulinum toxin A (BTX-A) remain subjects of controversy. The meta-analysis was performed to assess the efficacy and safety of a novel intravesical instillation of BTX-A for m…
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Botulinum Neurotoxin Type A Combined with Platelet-Rich Plasma Promotes Hair Follicle Growth and Regeneration via STMN1 Modulation and Wnt/β-Catenin Pathway Activation.
There is currently limited knowledge about the combined effect of Botulinum toxin type A (BoNT/A) and Platelet-rich plasma (PRP) on hair follicle growth and reconstruction. This study aimed to investigate the impact of BoNT/A in conjunction…
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Preservation solution protects isolated hair micrografts by inhibiting apoptosis of hair bulb.
[AIMS] To investigate the effectiveness of histidine-tryptophan-ketoglutarate (HTK) solution compared to Ringer's (RS) solution for preserving isolated hair follicles (HFs), focusing on structural integrity, cell viability, apoptosis preven…
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Follicular Unit Excision Hair Removal of Unwanted Facial Terminal Hair in Five Facial Areas: A Retrospective Multicenter Cohort Study.
[BACKGROUND] Conventional epilation methods commonly encounter challenges in achieving permanent removal of unwanted facial terminal hair (uFTH), particularly when it is interspersed among normal hairs. [OBJECTIVE] To assess the safety and…
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Outcomes after liposuction-based treatment of lymphedema: a systematic review and meta-analysis.
[BACKGROUND] Lymphedema, a chronic condition involving lymphatic fluid accumulation, affects over 250 million people worldwide. Liposuction (LS), introduced in 1989, offers a minimally invasive option for non-pitting lymphedema by reducing …
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Treatment of Delayed Hypersensitivity After Injection of Nasal Fillers.
[BACKGROUND] Soft tissue filler injection is the second most commonly performed cosmetic procedure worldwide, with augmentation rhinoplasty being the most common filling surgery in Asian countries because Asians predominantly have a low nas…
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Isolated spinal artery aneurysm: etiology, clinical characteristics, and outcomes.
[OBJECTIVE] Isolated spinal aneurysms (ISAs) are rare causes of subarachnoid hemorrhage (SAH), which encompass a highly heterogeneous group of clinical entities with multifarious pathogeneses, clinical characteristics, and treatment strateg…
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Clinical application of digital technology in the use of anterolateral thigh lobulated perforator flaps to repair complex soft tissue defects of the limbs.
[BACKGROUND] It is challenging to repair wide or irregular defects with traditional skin flaps, and anterolateral thigh (ALT) lobulated perforator flaps are an ideal choice for such defects. However, there are many variations in perforators…
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A Data-Driven Model with Hysteresis Compensation for IRIS Robot.
Retinal microsurgery is a high-precision surgery performed on a delicate tissue requiring the skill of highly trained surgeons. Given the restricted range of instrument motion in the confined intraocular space, snake-like robots may prove t…
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Development and validation of a predictive nomogram for vascular crises in oral and maxillofacial cancer patients undergoing free flap surgery.
[OBJECTIVE] To develop and validate a predictive model for identifying vascular crises following free tissue flap transplantation in patients undergoing surgery for oral and maxillofacial tumors. [METHODS] This retrospective cohort study u…
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Botulinum Toxin Injection Technique for Reducing the Masseter Size and Enhancing the Jawline.
[BACKGROUND] The injection of botulinum toxin into the masseter muscle is an important method for improving hypertrophy. However, some patients may experience adverse reactions, such as sagging of the lower jaw. Therefore, we proposed a met…
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Acupuncture for Meige syndrome: A case report.
[INTRODUCTION] Meige syndrome (MS) is a cranial dystonia disorder characterized by blepharospasm and oromandibular dystonia. Current treatments include botulinum toxin therapy, oral medications, and surgical interventions. Here, we present …
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Risk Factors and Hazards of Recipient-Area Perifollicular Erythema After Hair Transplantation: A Multicenter Retrospective Cohort Study.
[BACKGROUND] Recipient-area perifollicular erythema (RPE) may delay graft growth after hair transplantation. However, there is currently a lack of observational clinical studies of RPE. [OBJECTIVE] To study the clinical features and risk f…
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Characterization and Risk Factors of Folliculitis after Hair Transplantation: A Multicenter Retrospective Study.
[BACKGROUND] Postoperative folliculitis is a common complication of hair transplantation (HT) requiring effective preventive interventions. This study characterized postoperative folliculitis and determined risk factors in patients undergoi…