Epidemiology of alopecia areata, ophiasis, totalis, and universalis: A systematic review and meta-analysis.
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TL;DR
A systematic review of all published cohort and cross-sectional studies that analyzed AA and its subtypes found that AA prevalence is lower in adults than children, is increasing over time, and significantly differs by region.
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📑 인용한 논문 (6) ▾
- Illness Perception, Emotional Distress, and Obsessive-Compulsive Symptomatology in Patient… Behavioral sciences (Basel, Switzerland) · 2026
- Global, regional, and national burden of alopecia areata from 1990 to 2021: An analysis fr… JAAD international · 2026
- The Evolving Global Burden of Alopecia Areata in Young Adults: High-Income Nations Bear th… Annals of dermatology · 2026
- Dermatologists' Perspectives and Real-World Assessment of Alopecia Areata Severity in Adul… Dermatology and therapy · 2026
- Long-Term Efficacy and Safety of Ritlecitinib in Adults and Adolescents with Alopecia Area… American journal of clinical dermatology · 2026
- Analysis of trichoscopic images using deep neural networks for the diagnosis and activity … Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG · 2026
연도별 인용 (2020–2026) · 합계 317
OpenAlex 토픽 ·
Hair Growth and Disorders
Autoimmune Bullous Skin Diseases
Dermatology and Skin Diseases
Abstract 🌐 Abstract
[BACKGROUND] Alopecia areata (AA) is a common autoimmune alopecia with heterogeneous severity and distribution. Previous studies found conflicting results about AA epidemiology.
[OBJECTIVE] To determine the prevalence, incidence, and predictors of AA, alopecia totalis, alopecia ophiasis, and alopecia universalis.
[METHODS] A systematic review of all published cohort and cross-sectional studies that analyzed AA and its subtypes. MEDLINE, Embase, LILACS, Scopus, Cochrane Library, and GREAT were searched. At least 2 reviewers performed study title/abstract review and data extraction. Random-effects meta-analysis was used because of significant heterogeneity (I = 99.97%).
[RESULTS] Ninety-four studies met the inclusion criteria. The pooled prevalence (95% confidence interval, N) of AA overall was 2.11% (1.82-2.42, N = 302,157,365), with differences of population-based (0.75% [0.49-1.06%], N = 301,173,403) and clinic-based (3.47% [3.01-3.96], N = 983,962) studies. The prevalences of alopecia totalis, ophiasis, and universalis were 0.08% (0.04-0.13, N = 1,088,149), 0.02% (0.00-0.06, N = 1,075,203), and 0.03% (0.01-0.06, N = 1,085,444), respectively. AA prevalence (95% confidence interval) increased over time (<2000: 1.02% [0.85-1.22]; 2000-2009: 1.76% [1.51-2.03]; >2009: 3.22% [2.59-3.92]; P < .0001) and differed by region. AA prevalence was significantly lower in adults (1.47% [1.18-1.80]) than children (1.92% [1.31-2.65]; P < .0001).
[CONCLUSIONS] AA affects 2% of the global population. AA prevalence is lower in adults than children, is increasing over time, and significantly differs by region.
[OBJECTIVE] To determine the prevalence, incidence, and predictors of AA, alopecia totalis, alopecia ophiasis, and alopecia universalis.
[METHODS] A systematic review of all published cohort and cross-sectional studies that analyzed AA and its subtypes. MEDLINE, Embase, LILACS, Scopus, Cochrane Library, and GREAT were searched. At least 2 reviewers performed study title/abstract review and data extraction. Random-effects meta-analysis was used because of significant heterogeneity (I = 99.97%).
[RESULTS] Ninety-four studies met the inclusion criteria. The pooled prevalence (95% confidence interval, N) of AA overall was 2.11% (1.82-2.42, N = 302,157,365), with differences of population-based (0.75% [0.49-1.06%], N = 301,173,403) and clinic-based (3.47% [3.01-3.96], N = 983,962) studies. The prevalences of alopecia totalis, ophiasis, and universalis were 0.08% (0.04-0.13, N = 1,088,149), 0.02% (0.00-0.06, N = 1,075,203), and 0.03% (0.01-0.06, N = 1,085,444), respectively. AA prevalence (95% confidence interval) increased over time (<2000: 1.02% [0.85-1.22]; 2000-2009: 1.76% [1.51-2.03]; >2009: 3.22% [2.59-3.92]; P < .0001) and differed by region. AA prevalence was significantly lower in adults (1.47% [1.18-1.80]) than children (1.92% [1.31-2.65]; P < .0001).
[CONCLUSIONS] AA affects 2% of the global population. AA prevalence is lower in adults than children, is increasing over time, and significantly differs by region.
- 표본수 (n) 302,157,365
- p-value P < .0001
- 연구 설계 systematic review
A systematic review of all published cohort and cross-sectional studies that analyzed AA and its subtypes found that AA prevalence is lower in adults than children, is increasing over time, and signif
APA 7
Lee, H. H., Gwillim, E., Patel, K. R., Hua, T., Rastogi, S., Ibler, E., & Silverberg, J. I. (2020). Epidemiology of alopecia areata, ophiasis, totalis, and universalis: A systematic review and meta-analysis.. Journal of the American Academy of Dermatology, 82(3), 675-682. https://doi.org/10.1016/j.jaad.2019.08.032
Vancouver
Lee HH, Gwillim E, Patel KR, Hua T, Rastogi S, Ibler E, et al. Epidemiology of alopecia areata, ophiasis, totalis, and universalis: A systematic review and meta-analysis. Jour. Amer. Acad. Derm.. 2020;82(3):675-682. doi:10.1016/j.jaad.2019.08.032
AMA 11
Lee HH, Gwillim E, Patel KR, Hua T, Rastogi S, Ibler E, et al. Epidemiology of alopecia areata, ophiasis, totalis, and universalis: A systematic review and meta-analysis. Jour. Amer. Acad. Derm.. 2020;82(3):675-682. doi:10.1016/j.jaad.2019.08.032
Chicago
Lee, H. H., Gwillim, E., Patel, K. R., Hua, T., Rastogi, S., Ibler, E., and Silverberg, J. I.. 2020. "Epidemiology of alopecia areata, ophiasis, totalis, and universalis: A systematic review and meta-analysis." Journal of the American Academy of Dermatology 82 (3): 675-682. https://doi.org/10.1016/j.jaad.2019.08.032
MLA 9
Lee, H. H., et al. "Epidemiology of alopecia areata, ophiasis, totalis, and universalis: A systematic review and meta-analysis." Journal of the American Academy of Dermatology, vol. 82, no. 3, 2020, pp. 675-682. doi:10.1016/j.jaad.2019.08.032.
PMID
31437543 ↗
추출된 의학 개체 (NER)
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| 유형 | 영어 표현 | 한국어 / 풀이 | UMLS CUI | 출처 | 등장 |
|---|---|---|---|---|---|
| 질환 | alopecia areata
|
원형 탈모증 | dict | 2 |
🏷️ 키워드 / MeSH 📖 같은 키워드 OA만
인용 관계
그래프 OA 노드: 6/8 (75%)
· 참조 0편 · 후속 6편
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