The effect of CD34+ cell-containing autologous platelet-rich plasma injection on pattern hair loss: a preliminary study.
4/5 보강
TL;DR
This data indicates that activation of activated autologous platelet‐rich plasma (PRP) has the potential to induce the proliferation of dermal papilla cells, which is an important factor in active hair growth.
PICO 자동 추출 (휴리스틱, conf 2/4)
유사 논문P · Population 대상 환자/모집단
13 patients with pattern hair loss, and 13 patients were treated with interfollicular placental extract injection as a control.
I · Intervention 중재 / 시술
interfollicular placental extract injection as a control
C · Comparison 대조 / 비교
추출되지 않음
O · Outcome 결과 / 결론
추출되지 않음
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연도별 인용 (2013–2025) · 합계 121
OpenAlex 토픽 ·
Hair Growth and Disorders
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This data indicates that activation of activated autologous platelet‐rich plasma (PRP) has the potential to induce the proliferation of dermal papilla cells, which is an important factor in active hai
- p-value P < 0.0001
APA
Jin-Soo Kang, Zhenlong Zheng, et al. (2014). The effect of CD34+ cell-containing autologous platelet-rich plasma injection on pattern hair loss: a preliminary study.. Journal of the European Academy of Dermatology and Venereology : JEADV, 28(1), 72-9. https://doi.org/10.1111/jdv.12062
MLA
Jin-Soo Kang, et al.. "The effect of CD34+ cell-containing autologous platelet-rich plasma injection on pattern hair loss: a preliminary study.." Journal of the European Academy of Dermatology and Venereology : JEADV, vol. 28, no. 1, 2014, pp. 72-9.
PMID
23279091 ↗
Abstract 한글 요약
[BACKGROUND] Mobilized CD34+ cells in peripheral blood have angiogenic potential, which is an important factor in active hair growth. In addition, activated autologous platelet-rich plasma (PRP) has been reported to induce the proliferation of dermal papilla cells.
[OBJECTIVES] To investigate the clinical efficacy of interfollicular injection of CD34+ cell-containing PRP preparation for pattern hair loss.
[PATIENTS AND METHODS] CD34+ cell-containing PRP preparation was injected on the scalps of 13 patients with pattern hair loss, and 13 patients were treated with interfollicular placental extract injection as a control. The numbers of platelets in PRP were microscopically counted and CD34+ cells were evaluated with flow cytometry.
[RESULTS] Three months after the first treatment, the patients presented clinical improvement in the mean number of hairs, 20.5 ± 17.0% (P < 0.0001), mean hair thickness, 31.3 ± 30.1% (P < 0.0001), and mean two-point score, 84.4 ± 51.7% (P < 0.0001) compared with baseline values. At 6 months, the patients presented clinical improvement in mean hair count, 29.2 ± 17.8% (P < 0.0001), mean hair thickness, 46.4 ± 37.5% (P < 0.0001), and mean two-point score, 121.3 ± 66.8% (P < 0.0001) compared with baseline. The MIXED procedure revealed that CD34+ cell-containing PRP treatment presented a higher degree of improvement than placental extract treatment in hair thickness (P = 0.027) and overall clinical improvement (P = 0.023).
[CONCLUSION] Our data suggest that the interfollicular injection of autologous CD34+ cell-containing PRP preparation has a positive therapeutic effect on male and female pattern hair loss without remarkable major side-effects.
[OBJECTIVES] To investigate the clinical efficacy of interfollicular injection of CD34+ cell-containing PRP preparation for pattern hair loss.
[PATIENTS AND METHODS] CD34+ cell-containing PRP preparation was injected on the scalps of 13 patients with pattern hair loss, and 13 patients were treated with interfollicular placental extract injection as a control. The numbers of platelets in PRP were microscopically counted and CD34+ cells were evaluated with flow cytometry.
[RESULTS] Three months after the first treatment, the patients presented clinical improvement in the mean number of hairs, 20.5 ± 17.0% (P < 0.0001), mean hair thickness, 31.3 ± 30.1% (P < 0.0001), and mean two-point score, 84.4 ± 51.7% (P < 0.0001) compared with baseline values. At 6 months, the patients presented clinical improvement in mean hair count, 29.2 ± 17.8% (P < 0.0001), mean hair thickness, 46.4 ± 37.5% (P < 0.0001), and mean two-point score, 121.3 ± 66.8% (P < 0.0001) compared with baseline. The MIXED procedure revealed that CD34+ cell-containing PRP treatment presented a higher degree of improvement than placental extract treatment in hair thickness (P = 0.027) and overall clinical improvement (P = 0.023).
[CONCLUSION] Our data suggest that the interfollicular injection of autologous CD34+ cell-containing PRP preparation has a positive therapeutic effect on male and female pattern hair loss without remarkable major side-effects.
🏷️ 키워드 / MeSH 📖 같은 키워드 OA만
인용 관계
그래프 OA 노드: 5/6 (83%)
· 참조 0편 · 후속 5편
이 논문을 인용한 후속 연구 6
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- A Systemic Review on Topical Marketed Formulations, Natural Products, and Oral Supplements to Preven…
- Evaluation of the safety and efficacy of concentrated growth factors for hair growth promotion in an…
- Advances in Research on Concentrated Growth Factor Applications for Androgenetic Alopecia Treatment:…
- Updates in Treatment for Androgenetic Alopecia.
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