Treatment of Depression with Botulinum Toxin.

Toxins 2022 Vol.14(6)

Wollmer MA, Magid M, Kruger THC, Finzi E

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Abstract

Injection of botulinum toxin (BoNT) into the glabellar region of the face is a novel therapeutic approach in the treatment of depression. This treatment method has several advantages, including few side effects and a long-lasting, depot-like effect. Here we review the clinical and experimental evidence for the antidepressant effect of BoNT injections as well as the theoretical background and possible mechanisms of action. Moreover, we provide practical instructions for the safe and effective application of BoNT in the treatment of depression. Finally, we describe the current status of the clinical development of BoNT as an antidepressant and give an outlook on its potential future role in the management of mental disorders.

추출된 의학 개체 (NER)

유형영어 표현한국어 / 풀이UMLS CUI출처등장
시술 botulinum toxin 보툴리눔독소 주사 dict 2

MeSH Terms

Antidepressive Agents; Botulinum Toxins, Type A; Depression; Humans; Injections; Mental Disorders; Neuromuscular Agents

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