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Effects of glabellar botulinum toxin injections on resting-state functional connectivity in borderline personality disorder.
Meta-analyses suggest a sustained alleviation of depressive symptoms through glabellar botulinum toxin (BTX) injections. This can be explained by the disruption of facial feedback loops, which may moderate and reinforce the experience of ne…
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Botulinum Toxin Therapy for Psychiatric Disorders in Clinical Practice: A Retrospective Case Study.
Inhibiting the facial expression of negative emotions via botulinum toxin A (BTX) has been shown to mitigate symptoms of clinical depression in randomized controlled trials. This retrospective case study sought to reproduce the beneficial e…
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Clinical effects of glabellar botulinum toxin injections on borderline personality disorder: A randomized controlled trial.
[BACKGROUND] Inhibition of frowning via injections of botulinum toxin A (BTX) into the glabellar region has shown beneficial effects in the treatment of major depression. Preliminary research suggests that improvements in the affective doma…
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Treatment of Depression with Botulinum Toxin.
Injection of botulinum toxin (BoNT) into the glabellar region of the face is a novel therapeutic approach in the treatment of depression. This treatment method has several advantages, including few side effects and a long-lasting, depot-lik…
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Neuronal effects of glabellar botulinum toxin injections using a valenced inhibition task in borderline personality disorder.
Previous studies have indicated that glabellar botulinum toxin (BTX) injections may lead to a sustained alleviation of depression. This may be accomplished by the disruption of a facial feedback loop, which potentially mitigates the experie…
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The Use of Botulinum Toxin for Treatment of Depression.
A series of clinical studies have shown that botulinum toxin can treat major depression. Subjects suffering from unipolar depression may experience a quick, strong, and sustained improvement in the symptoms of depression after a single glab…
- Correction to: The Use of Botulinum Toxin for Treatment of Depression.
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Botulinum toxin for the management of depression: An updated review of the evidence and meta-analysis.
Botulinum toxin (BTX) treatment of glabellar frown lines is one of the most common procedures in aesthetic medicine. In addition to its cosmetic effect, the neurotoxin has been shown to have a positive influence on mood and affect. Several …
- Reply to: "Letter to the Editor: Claims about the effects of botulinum toxin on depression should raise some eyebrows".
- Comment on effects of botulinum toxin type A on mood and cognitive function in patients with Parkinson's disease and depression.
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Postmarketing safety surveillance data reveals protective effects of botulinum toxin injections against incident anxiety.
Randomized controlled trials (RCTs) have shown an antidepressant effect of glabellar botulinum toxin (BoNT) injections. In the FDA Adverse Event Reporting System (FAERS) database, BoNT injection is associated with reduced incidence rates of…
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Postmarketing safety surveillance data reveals antidepressant effects of botulinum toxin across various indications and injection sites.
The World Health Organization estimates the number of people suffering from depression to be over 264 million. Current monoamine transmission modulating therapeutics, even with proper adherence and acceptable tolerability, are not effective…
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Botulinum Toxin as a Treatment for Depression in a Real-world Setting.
[OBJECTIVES] A series of randomized controlled trials have shown the efficacy of glabellar botulinum toxin (BTX) injection as a treatment for depression in women. We wanted to extend these findings and assess how they may be translated to a…
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Shrink that frown! Botulinum toxin therapy is lifting the face of psychiatry.
Treating glabellar frown lines with injections of botulinum toxin is the most frequently applied procedure in aesthetic medicine. In addition to its cosmetic effect, botulinum toxin may also positively modulate mood and affect, which may co…
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Botulinum toxin therapy of bipolar depression: A case series.
We and others have recently found that botulinum toxin injected into the brow muscles has significant antidepressant properties as compared to placebo in randomized controlled trials in patients with major depressive disorder. However, data…
- Botulinum toxin for depression: Does patient appearance matter?
- Can Botulinum Toxin Help Patients With Borderline Personality Disorder?
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Depression--An emerging indication for botulinum toxin treatment.
The treatment of glabellar frown lines with botulinum toxin injection is one of the most prevalent procedures in esthetic medicine. It is possible that the popularity of this intervention is not only owing to its cosmetic effect but also to…