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175건 · 최신순-
The Effects of Ovine-Derived Reinforced Tissue Matrix Surrounding Silicone-Based Implants in a Rat Prepectoral Reconstruction Model.
Silicone-based implants have been widely used in breast reconstruction but have also been associated with poorly understood complications, including pathologic foreign body responses such as capsular contracture. In this study, we leveraged…
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Theacrine protects vascular endothelial cells against oxidative damage after ischemic stroke by inhibiting Rac1 and activating Nrf2 pathway.
Ischemic stroke is a leading global health issue without a definitive treatment. Theacrine (TC), a purine alkaloid extracted from Chinese tea kucha (Camellia assamica var. kucha), has shown potential in brain health and is under investigati…
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Simulation-driven experiments resolve throttle pedal vibration issues.
This study investigates the resolution of accelerator pedal vibration issues during horn activation in vehicle tuning through finite element analysis combined with real-world test data. For certain facelift models experiencing NVH challenge…
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Aesthetic Correction of Mild Blepharoptosis: Balancing the Effect of Hering's Law.
[BACKGROUND] Disregarding the influence of Hering's law of equal innervation, which dictates conjugate movement of the eyelids during saccadic eye movements, in blepharoptosis correction leads to unsatisfactory surgical outcomes. The author…
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Medial Epicanthoplasty: A Modified Inverted Z-Plasty Technique to Create Ethnic Appropriate Medial Canthal Configuration.
[BACKGROUND] The medial epicanthal fold is a common anatomical feature in Asian populations, often coexisting with single eyelid configurations. Epicanthoplasty, combined with blepharoplasty, is a standard cosmetic procedure to create a lar…
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Septoaponeurotic Junctional Thickening Fixation Technique in 13,500 Asian Upper Blepharoplasties: Evidence-Based Outcomes Driving Technical Refinement.
[BACKGROUND] To evaluate the anatomical rationale and clinical efficacy of septoaponeurotic junctional thickening (SAJT) fixation technique in Asian upper blepharoplasty. [METHODS] Retrospective analysis of 13,500 consecutive cases (12,150…
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Application and Efficacy Observation of Autologous Bilateral Auricular Cartilage Combined with Nasal Septal Cartilage in Nasal Tip Shaping During Rhinoplasty.
[BACKGROUND] Due to the inherent fragility of septal and auricular cartilage, insufficient graft availability during surgery, and technical limitations in nasal tip framework construction, we modified the cartilage harvesting techniques and…
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Clinical Efficacy Analysis of Functional Rhinoplasty Assisted by Nasal Endoscopy.
[OBJECTIVE] To analyze the clinical effect of endoscopy-assisted functional rhinoplasty. [METHODS] Endoscopy-assisted functional rhinoplasty was performed in all patients. Deviated nasal septum was corrected, nasal septum cartilage graft w…
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Psychological Disorders Are a Non-negligible Factor in Medical Aesthetic Disputes.
[BACKGROUND] Psychological disorders play a crucial yet often overlooked role in medical aesthetic disputes. Patients with underlying psychological conditions may have unrealistic expectations, leading to dissatisfaction and legal conflicts…
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Breast implant microbiome profile correlates with foreign body response severity.
Biomedical implants significantly enhance quality of life for millions of individuals worldwide. However, maintaining long-term implant function remains challenging, and it is often due to a severe foreign body response, characterized by fi…
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Predictors of postoperative epileptic seizures after microsurgical treatment in supratentorial single cerebral cavernous malformations: a retrospective study.
[PURPOSE] Seizures are the most common symptom of supratentorial cerebral cavernous malformations (CCMs). This study aimed to investigate the predictors of seizure freedom in patients with single supratentorial CCMs after microsurgical trea…
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Clinical application and influencing factors of free flap transplantation for the reconstruction of skin and soft tissue defects: A retrospective cohort study.
Skin and soft tissue defects, often caused by trauma, infection, burns, or surgery, can significantly impair function and quality of life. Free flap transplantation is a key technique for reconstructing such defects, but its success is infl…
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Reconstruction of Bilateral Paranasal Skin and Soft Tissue Defects Using a Free Bilobed Thoracoacromial Artery Perforator Flap Following Multiple Cutaneous Squamous Cell Carcinomas Resection: A Case Report and Literature Review.
In recent years, the thoracoacromial artery perforator (TAAP) flap has emerged as a promising option for the reconstruction of facial defects, typically utilized in the form of a pedicled flap. However, there remains relatively limited expe…
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Autonomous Robot-Assisted Endodontic Microsurgery on First Molar in Complex Anatomical Scenarios: A Case Series.
Endodontic microsurgery (EMS) is an important approach for preserving teeth with failed root canal treatment. However, implementing minimally invasive osteotomies and accurate apicoectomies can be challenging in anatomically complex areas, …
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Robot-assisted augmented reality navigation for osteotomy and personalized guide-plate in mandibular reconstruction: a preclinical study.
[BACKGROUND] Oral and maxillofacial tumors, particularly those requiring mandibular reconstruction, present significant clinical challenges due to the complexities involved in achieving precise surgical outcomes and ensuring post-operative …
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Application of percutaneous lymphatic contrast-enhanced ultrasound in lymphovenous anastomosis microsurgery.
[OBJECTIVE] This study evaluated percutaneous lymphatic contrast-enhanced ultrasound (CEUS) for preoperative localization in preparation for lymphovenous anastomosis (LVA) microsurgery. [METHODS] Fourteen healthy volunteers and 14 patients…
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Lower early-stage rectal cancer surgical approaches: therapeutic options and cancer biomarker alterations.
[BACKGROUND] Low early-stage rectal cancer (LeREC), typically referring to pTis and pT1 tumors without nodal involvement or lymphovascular/perineural invasion and confined to the mucosa, can potentially be treated with transanal local excis…
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Primary intestinal-type adenocarcinoma of the larynx: A case report and literature review.
Primary intestinal-type adenocarcinoma (ITAC) of the larynx is extremely rare and requires differentiation from metastatic intestinal adenocarcinoma due to their similar morphological and immunophenotypic features. This case report describe…
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Endodontic microsurgery utilizing an autonomous robotic system for the maxillary second molar: a case report.
[BACKGROUND] Endodontic microsurgery (EMS) is a widely utilized technique for addressing periapical periodontitis that is unresponsive to conventional root canal treatment. Nevertheless, achieving precise root apex location and resection ca…
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Tentorial Dural Arteriovenous Fistulas: A Retrospective Cohort Study.
[BACKGROUND AND OBJECTIVES] With advancements in endovascular techniques, an increasing number of tentorial dural arteriovenous fistulas (TDAVFs) can now be successfully treated with endovascular intervention alone. In this study, we presen…
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A comparative study on the clinical outcomes of local flap transfer and free flap transplantation for the repair of lower limb bone exposure wounds.
[OBJECTIVE] To compare and analyze the clinical outcomes of local flap transfer and free flap transplantation for the repair of lower limb bone exposure wounds. [METHODS] A retrospective study was conducted on 90 patients with lower limb b…
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A novel injectable Sericin/Nano-hydroxyapatite hydrogel as a dermal filler for soft tissue augmentation.
With the rapid advancement of medical aesthetics, particularly the expanding market for wrinkle reduction and facial rejuvenation, the demand for dermal fillers continues to rise. Injectable materials derived from natural sources offer sign…
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Unilateral Blepharoptosis Combined With Malignant Exophthalmos After Botulinum Toxin Injection to Glabellar Lines: A Case Report.
[BACKGROUND] The ocular adverse reactions caused by the diffusion of BoNT-A injection are self-limiting, with symptoms ameliorating over time. Thyroid-associated ophthalmopathy (TAO) is an autoimmune disease characterized by symptoms such a…
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A novel single-domain antibody obtained from immune Bactrian camels against botulinum toxin type A using SPR-based screening method.
Botulinum neurotoxin (BoNT) is a highly lethal toxin produced by the anaerobic bacterium Clostridium botulinum, which leads to nerve paralysis following poisoning. At present, there is no specific drug officially approved. Antibodies, parti…
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Myospasm and Fasciculation After Botulinum Toxin Injection.
Botulinum toxin type A (BTA) is commonly used to treat dystonia; however, reports of dystonia caused by BTA are rare. In this case study, the authors aimed to illustrate the instances of dystonia after cosmetic injections of BTA. Three case…
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Taraxacum mongolicum Hand.-Mazz. extract disrupts the interaction between triple-negative breast cancer cells and tumor-associated macrophages by inhibiting RAC2/NF-κB p65/p38 MAPK pathway.
[ETHNOPHARMACOLOGICAL RELEVANCE] Taraxacum mongolicum Hand.-Mazz., generally known as dandelion, is a herb renowned for its pharmacological properties, including detoxifying and anti-inflammatory effects. Historically, this herb has been ex…
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Nonsurgical Therapies for Spastic Cerebral Palsy: A Network Meta-Analysis.
[CONTEXT] Spastic cerebral palsy (SCP) presents daily challenges because of spasms, impacting motor function. Although multiple nonsurgical therapies exist, their comparative efficacy remains uncertain. [OBJECTIVE] To compare the effective…
- Correction to: Dysphagia and Muscle Weakness Caused by Botulinum Toxin Poisoning after Cosmetic Injection: Three Case Reports and Clinical Warnings.
- Intralesional Insulin Is Superior to Intralesional Botulinum Toxin-A in the Treatment of Keloids.
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Rac1 in gastric cancer: a molecular driver of invasion, EMT, and therapeutic resistance.
Gastric cancer (GC) ranks as the fifth most common cancer worldwide and is the third main cause of cancer-related mortality, posing a substantial burden to global public health. Research suggests that targeted therapy and immunotherapy may …