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175건 · 최신순-
P21-activated kinase 4: a potent oncogene, molecular mechanisms and opportunities for targeted therapy.
[UNLABELLED] P21-activated kinase 4 (PAK4), recognized as a key effector protein of the Rho family of small G proteins Cell division regulatory protein 42 homologue (Cdc42) and Ras-related C3 botulinum toxin substrate 1 (Rac1), is a serine/…
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Efficacy and safety of intradermal botulinum toxin A for post-acne erythema: a split-face randomized controlled trial.
[INTRODUCTION] Post-acne erythema (PAE) is a common aesthetic sequela in patients with acne. Although numerous treatments for PAE have been investigated, the efficacy of intradermal botulinum toxin A (BTX-A) remains controversial. This stud…
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Dysphagia and Muscle Weakness Caused by Botulinum Toxin Poisoning after Cosmetic Injection: Three Case Reports and Clinical Warnings.
Botulinum toxin (BoNT), a neurotoxic protein produced by Clostridium botulinum, is widely used for cosmetic and therapeutic purposes, including managing muscle hyperactivity, movement disorders, and chronic migraines by blocking acetylcholi…
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Characterization and Classification of Frontal Hairline Contours and Growth Directions in Chinese Women.
[BACKGROUND] Hair transplantation has become a major method for improving upper facial contour. Hairline contour (HC) and hair growth direction (HGD) are the main factors affecting postoperative aesthetic outcomes. However, studies on natur…
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Increasing Facial Attractiveness by Lateralizing the Auricle-Analyzing the Pan-Facial Effects of the Postauricular Injection Technique in Chinese Patient Populations.
[BACKGROUND] The postauricular injection technique is a needle-based technique that places soft tissue fillers behind the ears into the supra-periosteal plane of the mastoid process of the temporal bone. The resulting clinical effect pushes…
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A retrospective study on different kind of cartilage frameworks on Asian rhinoplasty.
[BACKGROUND] The character of Asian nose usually presents low projection of tip, short columellar, and short nose, necessitating the construction of a cartilage framework to achieve optimal results. The objective of this study was to evalua…
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A Bibliometric Review of Software Tools in Plastic Surgery: How They Benefit Surgeons and Improve Practice from 2004 to 2024.
[BACKGROUND] Bibliometric analyses of software applications in plastic surgery are relatively limited. This study aims to address this gap by summarizing current research trends and providing insights that may guide future developments in t…
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Complications and patient-reported outcomes after radiotherapy in breast cancer patients undergoing implant-based breast reconstruction: a retrospective study from a large Chinese breast disease center.
[BACKGROUND] Postmastectomy radiation therapy (PMRT) can influence the outcome of implant-based breast reconstruction (IBBR). This study aims to investigate the complications and patient-reported outcomes (PROs) following PMRT between direc…
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Research progress on anatomy reconstruction of rat orthotopic liver transplantation.
Rat orthotopic liver transplantation (ROLT) serves as an ideal animal model and has gained popularity in addressing complications and perioperative treatments related to clinical liver transplantation. Through extensive research on ROLT mod…
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Prognostic impact of sodium fluorescein-guided microsurgery on cognitive function, neuropeptide dynamics, and short-term outcomes in brain glioma patients.
This study conducted a retrospective analysis on 107 brain glioma patients treated from January 2018 to February 2020 to assess the impact of sodium fluorescein-guided microsurgery on postoperative cognitive function and short-term outcomes…
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Adult Central Neurocytomas: Clinical Features and Long-Term Treatment Outcomes in Different Age Groups.
[BACKGROUND] Central neurocytomas (CNs) usually occur in young adults, and the clinical characteristics and surgical outcomes of patients in different age groups may be different. [METHODS] This study was undertaken to compare the clinical…
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High-Precision Implant Cavity Fabrication Using Femtosecond Lasers.
This study aims to enhance the precision of implant cavity preparation, addressing a notable challenge in the current state of the field by utilizing femtosecond lasers. The application of femtosecond lasers in implant cavity preparation h…
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Dynamic Repair Surgery for Late-Stage Facial Paralysis: Advances in Restoring Movement and Function.
Facial paralysis results from congenital or acquired facial nerve damage, leading to significant cosmetic and functional deficits. Surgical resection of parotid and midface tumors can cause facial paralysis, necessitating effective treatmen…
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Impact of Microsurgery and Postoperative Radiotherapy on Neurological Function in Intramedullary Spinal Cord Gliomas.
[OBJECTIVE] To assess the clinical efficacy of combined microsurgery and postoperative radiotherapy for the treatment of intramedullary spinal gliomas and its impact on neurological function. [STUDY DESIGN] An observational study. Place an…
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The Utility of Indocyanine Green Angiography in Breast Reconstruction to Detect Mastectomy Skin Flap Necrosis and Free Flap Perfusion: An Umbrella Review.
Two of the greatest challenges in breast reconstruction are mastectomy skin flap necrosis (MSFN) and autologous flap failure. This review summarizes current evidence regarding the usage of indocyanine green angiography (ICGA) in breast reco…
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Analysis of changes in bone mineral density and cortical bone thickness after reconstruction of the mandible with fibula, is condyle preservation a critical influence factor?
[OBJECTIVE] This study aimed to investigate the features of bone mineral density (BMD) and cortical bone thickness in grafted fibula. [MATERIALS AND METHODS] Eighty-six patients who underwent mandibular reconstruction using vascularized fi…
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Endodontic Microsurgery with the Aid of Dynamic Navigation System Using Minimally Invasive Incision Approach in Anatomically Complex Scenarios: A Case Series.
Endodontic microsurgery (EMS) is an alternative treatment option for previously treated teeth with persistent periapical disease, offering a favorable prognosis. However, it can be particularly challenging in anatomically complex cases, ris…
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Visualization Mapping and Current Trends of Facial Contouring Procedures: A Bibliometric Analysis Based on Web of Science.
[BACKGROUND] Facial contouring procedures become popular in recent years, but there has been no bibliometric analysis focused on this field. [OBJECTIVE] Construct visualization maps and analyze the hotspots and current trends in this field…
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Performance assessment of an injectable hyaluronic acid/polylactic acid complex hydrogel with enhanced biological properties as a dermal filler.
Injectable hyaluronic acid (HA) hydrogel plays an important role in dermal filling. However, conventional HA dermal fillers mostly lack bio-functional diversity and frequently cause adverse reactions because of the chemical stiffness of hig…
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Objective Noninvasive Measurement of the Volumizing Effect of a Dermal Filler: An In Vivo Study.
[BACKGROUND] Information about the volumizing effects of dermal fillers is critical for physicians' understanding of product features and prudent decision-making in clinical practice. It is important for material engineers to develop and op…
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Improvement of neurogenic urinary dysfunctions in female rats treated with an injection of botulinum toxin A at the epicenter of the spinal cord injured site.
[OBJECTIVE] To assess the effect of an injection of botulinum toxin A (BoNT/A) at the epicenter of the spinal cord injury (SCI) site on the recovery of lower urinary tract function in female rats with thoracic SCI. [MATERIALS AND METHODS] …
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Evaluation of therapeutic benefits of botulinum toxin for foot dystonia associated with Parkinson's disease.
[BACKGROUND] Foot dystonia occurs in patients with Parkinson's disease (PD) and leads to pain, malformation, and difficulty with walking. Botulinum toxin injections may be effective for foot dystonia, but the extent of improvement and effec…
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Pulmonary Embolism after Botulinum Toxin Treatment for Leg Muscle Hypertrophy.
Leg muscle hypertrophy is a unique physical symptom in East Asian women. Compared with traditional surgical treatment for calf muscle hypertrophy, botulinum toxin is widely favored by East Asian women because of its minimal trauma and signi…
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Intradermal Injection in Balding Region Versus Intramuscular Injection in Surrounding Muscles: A Split-Scalp, Randomized Trial on BoNT for Androgenetic Alopecia.
[INTRODUCTION] Recent advancements in androgenetic alopecia (AGA) treatment have highlighted the efficacy of botulinum toxin (BoNT). However, inconsistencies in injection sites and depths warrant attention. It remains unclear which injectio…
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SNARE proteins: Core engines of membrane fusion in cancer.
Vesicles are loaded with a variety of cargoes, including membrane proteins, secreted proteins, signaling molecules, and various enzymes, etc. Not surprisingly, vesicle transport is essential for proper cellular life activities including gro…
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Assessing the efficacy and quality of Life improvements of botulinum toxin type a with topical minoxidil versus topical minoxidil in male androgenetic alopecia: a randomized controlled trial.
Androgenetic alopecia (AGA) is a common type of hair loss in men and efficacy and safety of current medical treatment remain limited. Therefore, the present study aimed to investigate the efficacy and safety of botulinum toxin type A (BTA) …
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The progress in epidemiological, diagnosis and treatment of primary hemifacial spasm.
Hemifacial Spasm is a neurological disorder characterized by persistent and rhythmic spasms of the facial muscles, significantly affecting the patient's quality of life. This condition can be classified into primary and secondary types; thi…
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[Research progress of botulinum toxin A in the therapeutic applications of oral diseases].
Botulinum toxin A (BTX-A) is a powerful neurotoxin produced by Clostridium botulinum, which can relieve muscle spasm or limit gland secretion by inhibiting the release of acetylcholine at the neuromuscular/glandular junction. In addition, B…
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Botulinum toxin combined with static progressive stretching improves fibrous stiffness of knee joint in rats through TGF-β1/Smad pathway.
Joint stiffness and fibrosis are common complications that affect mobility and quality of life, necessitating effective therapeutic strategies to alleviate these issues. The study aimed to observe the therapeutic effect of static progressiv…
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Recipient site scalp necrosis: A rare postoperative complication of hair transplantation.
[BACKGROUND] Recipient area scalp necrosis is considered a potential complication of hair transplantation, but has rarely been reported. A small number of patients have developed scalp necrosis after hair transplantation with the widely use…