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Prevalence and Utilization of Obturator Artery Anatomic Variant in Autologous Breast Reconstruction.
[BACKGROUND] The objective of this study is to quantify the prevalence and describe the utilization of an anatomic vascular variant in which the obturator artery (OA) arises from the trunk of the deep inferior epigastric artery (DIEA) in s…
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Pilot study of minimum occlusive force of vascular clamps on arterial vessels in rats.
Our aims were to determine the accuracy of an improved formula for determining the minimum occlusive force (MOF) of a vascular clamp on rats' abdominal aortas, compare our findings with the calculated theoretical MOF, and provide reference …
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Beyond botulinum neurotoxin A for chemodenervation of the bladder.
[PURPOSE OF REVIEW] Botulinum neurotoxin A (BoNT/A), or Botox, is a popular option for overactive bladder (OAB) and neurogenic bladder (NGB) with or without incontinence. This review aims to discuss the clinical outcomes of BoNT in adult an…
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Rac3 Expression and its Clinicopathological Significance in Patients With Bladder Cancer.
Ras-related C3 botulinum toxin substrate 3 (Rac3) is overexpressed in malignancies and promotes tumor progression. However, the correlations between Rac3 expression and the clinicopathological characteristics and prognoses of patients with …
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Mycotoxin deoxynivalenol affects myoblast differentiation via downregulating cytoskeleton and ECM-integrin-FAK-RAC-PAK signaling pathway.
As a common mycotoxin, deoxynivalenol (DON) contaminates cereal grains and feed in field or during processing and storage. DON elicits a spectrum of adverse effects in animals including anorexia and growth retardation. Especially, the prese…
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Influence of extracellular nanovesicles derived from adipose-derived stem cells on nucleus pulposus cell from patients with intervertebral disc degeneration.
An increasing number of individuals are suffering from lower back and neck pain caused by intervertebral disc degeneration each year. Although the application of mesenchymal stem cells (MSCs) has provided desirable results in the treatment …
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Management of Unsatisfactory Postoperative Double Eyelid With Intralesional Corticosteroid Injection.
The present study was designed to observe the curative effect of early intralesional corticosteroid injection to treat unsatisfactory double eyelid. This retrospective, observational study included 30 female patients (age 22-35 years) rece…
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Effect of Transcutaneous Upper Eyelid Blepharoplasty on Blink Parameters and Lipid Layer Thickness.
This study aimed to investigate the effect of transcutaneous upper eyelid blepharoplasty on lipid layer thickness (LLT) and blink parameters in young women during the early postoperative period. This prospective study included 110 eyes of …
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Collagen scaffold combined with human umbilical cord-mesenchymal stem cells transplantation for acute complete spinal cord injury.
Currently, there is no effective strategy to promote functional recovery after a spinal cord injury. Collagen scaffolds can not only provide support and guidance for axonal regeneration, but can also serve as a bridge for nerve regeneration…
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Perspectives and Consensus among International Orthopaedic Surgeons during Initial and Mid-lockdown Phases of Coronavirus Disease.
With a lot of uncertainty, unclear, and frequently changing management protocols, COVID-19 has significantly impacted the orthopaedic surgical practice during this pandemic crisis. Surgeons around the world needed closed introspection, cont…
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Cervical Dystonia Caused by Chronic Nonunion C2 Fracture: A Case Report.
Chronic nonunion cervical fracture leading to cervical dystonia (CD) is very rare. This study reports a 72-year-old man who presented with 9-month history of progressively worsening neck tilting, neck tightness, neck pain, headache, and dif…
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Stress-Sensitive Protein Rac1 and Its Involvement in Neurodevelopmental Disorders.
Ras-related C3 botulinum toxin substrate 1 (Rac1) is a small GTPase that is well known for its sensitivity to the environmental stress of a cell or an organism. It senses the external signals which are transmitted from membrane-bound recept…
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Investigation of optimum transplant and extraction density based on the data from the donor area of Chinese androgenetic alopecia patients: a multicenter, retrospective study.
The rise in the incidence of androgenetic alopecia (AGA) in China has increased the inclination toward hair transplantation. To calculate the optimum density of hair follicles needed covering both the hairless area and the safe donor area (…
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Impact of Full-Incision Double-Eyelid Blepharoplasty on Tear Film Dynamics and Dry Eye Symptoms in Young Asian Females.
[BACKGROUND] Dry eye symptoms as a complication of double-eyelid blepharoplasty are controversial. This article evaluates tear film dynamics and changes in dry eye symptoms after cosmetic double-eyelid blepharoplasty in young Asian female. …
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Treatment for upper esophageal sphincter dysfunction in a patient with poststroke dysphagia: A case report.
[RATIONALE] Botulinum toxin injection is a widely used procedure for the treatment of the dysfunction of the upper esophageal sphincter (UES). Although the injection can be guided by ultrasound, electromyography, or computed tomography, suc…
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Crystal structure of the catalytic domain of the Weissella oryzae botulinum-like toxin.
Botulinum neurotoxins (BoNTs) are the most potent toxins known. So far, eight serotypes have been identified that all act as zinc-dependent endopeptidases targeting SNARE proteins and inhibiting the release of neurotransmitters. Recently, t…
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CT-Guided Chemical Thoracic Sympathectomy versus Botulinum Toxin Type A Injection for Palmar Hyperhidrosis.
[BACKGROUND] The present study aimed to evaluate and compare the efficacy of botulinum toxin type A (BTX-A) injection versus thoracic sympathectomy for idiopathic palmar hyperhidrosis. [METHODS] Fifty-one patients with idiopathic palmar …
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The Application of a Jigsaw Puzzle Flap Based on a Freestyle Perforator and an Aesthetic Unit for Large Facial Defects.
[BACKGROUND] The single-stage reconstruction of large facial defects remains a conundrum due to the balance between function and aesthetics after skin cancer radical resection. [OBJECTIVE] The goal of this study was to explore a novel surg…
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Identification of a Botulinum Neurotoxin-like Toxin in a Commensal Strain of Enterococcus faecium.
Botulinum neurotoxins (BoNTs), produced by various Clostridium strains, are a family of potent bacterial toxins and potential bioterrorism agents. Here we report that an Enterococcus faecium strain isolated from cow feces carries a BoNT-lik…
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Crystal Structure of Botulinum Neurotoxin A2 in Complex with the Human Protein Receptor SV2C Reveals Plasticity in Receptor Binding.
Botulinum neurotoxins (BoNTs) are a family of highly dangerous bacterial toxins, with seven major serotypes (BoNT/A-G). Members of BoNTs, BoNT/A1 and BoNT/B1, have been utilized to treat an increasing number of medical conditions. The clini…
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Efficacy of 8 Different Drug Treatments for Patients With Trigeminal Neuralgia: A Network Meta-analysis.
[OBJECTIVES] Trigeminal neuralgia (TN) is commonly seen in older persons and negatively influences their daily life. Although some research on the efficacy of TN drugs has been conducted, the optimal choice still remains uncertain. Therefor…
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Temporomandibular joint positional change accompanies post-surgical mandibular relapse-A long-term retrospective study among patients who underwent mandibular advancement.
[OBJECTIVE] This study evaluated the relationship between follow-up temporomandibular joint positional change and mandibular stability among patients who had orthognathic and orthodontic treatment for a skeletal Class II malocclusion. [MET…
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Adjustable V-Flap Epicanthoplasty Based on Desired Eyelid Morphology.
Eyelid shape is one key distinctive feature of the Asian eye. The presence of epicanthal folds is a common eyelid defect of Asians. Different surgical techniques have been developed to correct epicanthal folds. However, potential problems w…
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Prophylactic Levetiracetam for Seizure Control After Cranioplasty: A Multicenter Prospective Controlled Study.
[OBJECTIVE] To study efficacy and safety of prophylactic levetiracetam (LEV) administration in adults undergoing cranioplasty. [METHODS] We prospectively enrolled and randomly divided 200 adults undergoing cranioplasty into 2 groups: LEV (…
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The risk factors, etiology, and drug resistance of infection after plastic surgery, and corresponding measures.
[BACKGROUND] Explore the risk factors, etiology, and drug resistance of infection after plastic surgery, and present corresponding measures. [METHODS] We retrospectively analyzed 980 patients who underwent head and facial plastic surgery f…
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1α,25(OH)2D3 Induces Actin Depolymerization in Endometrial Carcinoma Cells by Targeting RAC1 and PAK1.
[BACKGROUND] Cell proliferation and motility require actin reorganization, which is under control of various signalling pathways including ras-related C3 botulinum toxin substrate 1 (RAC1), p21 protein-activated kinase 1 (PAK1) and actin re…
- An Easy and Cost-Effective Method to Perform the "No-Touch" Technique in Saline Breast Augmentation.
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[The clinical application of modified rhytidectomy incision in superficial parotid tumor surgery].
[OBJECTIVE] To evaluate the modified rhytidectomy incision in superficial parotidectomy. [METHOD] Thirty-five patients with superficial parotid tumor were included in this study. A modified rhytidectomy incision often used in facial plasti…
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Polyacrylamide hydrogel injection for breast augmentation: another injectable failure.
[BACKGROUND] Increasing complications of polyacrylamide hydrogel (PAAG) augmentation mammoplasty, such as chronic persistent infection, have recently caught the attention of both the medical field and the general public. [MATERIAL/METHODS]…