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An injectable photo-crosslinking silk hydrogel system with biphasic release of BTXA and 5-Fu promotes scarless wound healing.
Hypertrophic scarring is characterized by excessive dermal fibrosis and irregular collagen metabolism, mediated by fibroblasts derived from keloids. This condition typically arises from improper wound healing after deep burns, trauma, or su…
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A New Clinical Classification Method for Gynecomastia Based on Chest Appearance and MR/CT Images.
[BACKGROUND] Classification theories for gynecomastia often conflate breast ptosis degree with subcutaneous soft tissue composition, leading to further confusion in determining appropriate surgical regions and techniques. To address this, w…
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The Rise of Intelligent Plastic Surgery: A 10-Year Bibliometric Journey Through AI Applications, Challenges, and Transformative Potential.
[BACKGROUND] Driven by advancements in deep learning, surgical robots, and predictive modeling technologies, the integration of artificial intelligence (AI) and plastic surgery has expanded rapidly. Although AI shows the potential to enhanc…
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Prepectoral versus Subpectoral Dual-Plane Direct-to-Implant Breast Reconstruction with the TiLoop Bra: A Single-Center Prospective Cohort Study.
[BACKGROUND] Advancements in surgical techniques and materials have increased the use of direct-to-implant breast reconstruction after mastectomy. However, the optimal implant placement remains debated, with limited prospective studies comp…
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A new treatment strategy for mid-low rectal cancer patients exhibiting a clinical complete or near-complete response to neoadjuvant chemoradiotherapy: Transanal endoscopic microsurgery --A multicenter prospective case-control clinical trial by MONT-R.
[BACKGROUND] Total mesorectal excision is the standard surgery for locally advanced rectal cancer (LARC) after neoadjuvant chemoradiotherapy (nCRT), but it may lead to high complication rates and poor quality of life. This study evaluates w…
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Impact of anterior commissure invasion on the oncological efficacy of transoral laser microsurgery for T1 glottic cancer.
[BACKGROUND] In glottic laryngeal cancer, anterior commissure (AC) involvement affects prognosis. T staging ignores AC subregion involvement and TNM staging may not suit as an AC prognostic indicator. We explored how AC involvement degree i…
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FPM-RNet: Fused Photoacoustic and operating Microscopic imaging with cross-modality Representation and Registration Network.
Robot-assisted microsurgery is a promising technique for a number of clinical specialties including neurosurgery. One of the prerequisites of such procedures is accurate vision guidance, delineating not only the exposed surface details but …
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Comparative analysis of the therapeutic effect of antibiotic bone cement on Wagner grade 3 or 4 diabetic foot ulcer in heel and non-heel areas: a retrospective cohort study.
[BACKGROUND] Heel diabetic foot ulcers (hDFU) represent a particularly severe form of DFU, characterized by prolonged healing times and a significantly elevated risk of major amputation. Effective strategies to control infection and improve…
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Correction: Comparative analysis of the therapeutic effect of antibiotic bone cement on Wagner grade 3 or 4 diabetic foot ulcer in heel and non-heel areas: a retrospective cohort study.
[This corrects the article DOI: 10.3389/fendo.2025.1662731.].…
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Superficial Temporal Artery Pseudoaneurysm Following Facial Thread-Lift: A Rare Complication.
Thread lifting has become widely adopted worldwide as a nonsurgical facial rejuvenation technique due to its simplicity and short recovery period. However, despite its generally favorable safety profile, various complications may occur, wit…
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ENKD1 modulates innate immune responses through enhanced geranylgeranyl pyrophosphate synthase activity.
Inflammation is a crucial element of immune responses, with pivotal roles in host defenses against pathogens. Comprehensive understanding of the molecular mechanisms underlying inflammation is imperative for developing effective strategies …
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Atrophy Masseter Recovery by Electrical Stimulation Mediated M2-Like Macrophage Polarisation via JAK/PI3K/AKT Pathway.
[BACKGROUND] Atrophy of the masseter muscle can result in an aged facial appearance and diminished chewing function. Electrical stimulation (ES) is known for its ability to facilitate tissue healing and functional recovery, but its precise …
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[Mechanism of Xuebijing Injection in ameliorating acute lung injury by promoting efferocytosis based on proteomics and experimental validation].
This study aims to elucidate the mechanism by which Xuebijing Injection ameliorates acute lung injury(ALI) through promoting efferocytosis and suppressing inflammatory responses based on proteomics and experimental validation. Forty male Sp…
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Protruding or concealed: Defining ideal cranioauricular angle via a morphometric analysis in Asians.
[INTRODUCTION] The frontal appearance of ears, usually overlooked in facial aesthetics, has gained increasing attention among Asians. However, a consensus on the ideal cranioauricular angle is currently lacking. This study aims to investiga…
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Supramastoid Fascia as an Autologous Donor Site Alternative for Moderate Dorsal Augmentation: A Multicenter Prospective Study.
[BACKGROUND] Autologous fascia has been widely applied in rhinoplasty, yet prospective data on the supramastoid donor site remain scarce. This region provides a dense, pliable fascial layer with concealed scarring, potentially suitable for …
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A Bibliometric Analysis on Application of Robot-Assisted Surgery in Plastic Surgery.
In recent years, robot-assisted surgery has been a major advancement in surgery and has gradually become the preferred approach. The precise operation, minimal invasiveness, and the ability to perform the preoperative planning are its chara…
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Patient-Reported Outcomes and Complication Profiles of Implant-Based Breast Reconstruction in Patients With Postmastectomy Radiation Therapy.
[OBJECTIVE] This study aims to investigate the patient-reported outcomes (PROs) and complications of distinct implant-based breast reconstruction modality for patients with postmastectomy radiation therapy (PMRT). [METHODS] A retrospective…
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Inhibition of spinal Rac1 attenuates chronic inflammatory pain by regulating the activation of astrocytes.
[BACKGROUND] Spinal astrocyte-mediated neuroinflammation is an important mechanism for the maintenance of chronic inflammatory pain. Previous studies have investigated that Ras-related C3 botulinum toxin substrate 1 (Rac1) is closely relate…
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Comparison of the efficacy and adverse effects of unilateral or bilateral botulinum toxin injections for adductor spasmodic dysphonia: a systematic review and meta-analysis.
[PURPOSE] This study aims to aggregate and analyze existing clinical evidence to compare the efficacy and adverse effects of unilateral or bilateral botulinum toxin injections for the treatment of adductor spasmodic dysphonia (ADSD). [METH…
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Localisation of the centre of the highest region of muscle spindle abundance of anterior forearm muscles.
The centre of the highest region of muscle spindle abundance (CHRMSA) in the intramuscular nerve-dense region has been suggested as the optimal target location for injecting botulinum toxin A to block muscle spasms. The anterior forearm mus…
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An Ultrasonographic Analysis of the Deep Inferior Tendon in the Masseter Muscle: Implications for Botulinum Toxin Injections.
(1) Background: With the increasing aesthetic pursuit of facial features, the clinical use of Botulinum Toxin Type A (BoNT-A) injections for masseter hypertrophy has been on the rise. However, due to variations in masseter muscle structure …
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Intraoperative Cardiac Arrest During Liposuction: A Case Report.
[BACKGROUND] With the popularity of liposuction surgery, more awareness should be obtained regarding complications. Liposuction has been thought of as a safe procedure with a very low incidence of major complications. However, life-threaten…
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Major Clinical Adverse Events of Breast Implant in the Manufacturer and User Facility Device Experience Database.
[OBJECTIVE] Search the Manufacturer and User Facility Device Experience database to collect information on adverse events of breast implant. We analyzed the local complications and the breast implant illness (BII) of silicone breast implant…
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Elastic parameter identification of three-dimensional soft tissue based on deep neural network.
In the field of virtual surgery and deformation simulation, the identification of elastic parameters of human soft tissues is a critical technology that directly affects the accuracy of deformation simulation. Current research on soft tissu…
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Double Reinforcing Strategy with Perpendicular Plate of Ethmoid in Asian Secondary Unilateral Cleft Rhinoplasty: A Finite Element Analysis.
[BACKGROUND] Deviation and asymmetry relapse after secondary unilateral cleft rhinoplasty with septal extension graft is a common yet serious problem especially among Asian patients. Therefore, finding an effective approach to reduce deform…
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Academic visualization study of aesthetic medicine management and related legal research since 2000.
[BACKGROUND] Aesthetics medicine, a controversial branch of clinical medicine known for its high degree of commercialization, faces numerous conflicts, particularly in some developing countries. The global aesthetics medicine industry requi…
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Comparing Direct-to-Implant and Two-Stage Breast Reconstruction in the Australian Breast Device Registry.
[BACKGROUND] There remains a lack of clarity surrounding the benefits, risks, and outcomes between two-stage expander/implant reconstruction and single-stage direct-to-implant (DTI) reconstruction. This study used a national data set to exa…
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Effects of anterolateral femoral free flap transplantation on the repair of soft tissue defect of hands and feet and risk factors for flap necrosis.
[OBJECTIVE] To retrospectively analyze the effect of anterolateral femoral free flap transplantation in repairing hand and foot soft tissue defects and the risk factors for skin flap necrosis. [METHODS] The clinical data of 62 patients wit…
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Shifted-windows transformers for the detection of cerebral aneurysms in microsurgery.
[PURPOSE] Microsurgical Aneurysm Clipping Surgery (MACS) carries a high risk for intraoperative aneurysm rupture. Automated recognition of instances when the aneurysm is exposed in the surgical video would be a valuable reference point for …
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[Prospective study on the influence of dobutamine on blood perfusion in free flap repair of diabetic foot wounds].
To investigate the influence of clinical administration of dobutamine on blood perfusion in free flap repair of diabetic foot wounds. A prospective self-controlled study was conducted. From January to November 2022, 20 patients with diabet…