Physiopathology and current treatments of androgenetic alopecia: Going beyond androgens and anti-androgens.
4/5 보강
TL;DR
A review of the mechanisms and extrinsic factors involved in the AGA physiopathology as well as its conventional and emerging treatments and the association of different strategies could improve the treatment outcomes.
📑 코퍼스 인용 관계
· 인용됨 34
📑 인용한 논문 (6) ▾
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- Development of Ethosomes for the Topical Treatment of Androgenic Alopecia: Ethanol Effect … Pharmaceutics · 2025
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연도별 인용 (2019–2026) · 합계 128
OpenAlex 토픽 ·
Hair Growth and Disorders
Dermatologic Treatments and Research
Laser Applications in Dentistry and Medicine
A review of the mechanisms and extrinsic factors involved in the AGA physiopathology as well as its conventional and emerging treatments and the association of different strategies could improve the t
APA
Tatiele Katzer, Ademir Carvalho Junior Leite, et al. (2019). Physiopathology and current treatments of androgenetic alopecia: Going beyond androgens and anti-androgens.. Dermatologic therapy, 32(5), e13059. https://doi.org/10.1111/dth.13059
MLA
Tatiele Katzer, et al.. "Physiopathology and current treatments of androgenetic alopecia: Going beyond androgens and anti-androgens.." Dermatologic therapy, vol. 32, no. 5, 2019, pp. e13059.
PMID
31400254 ↗
Abstract 한글 요약
Androgenetic alopecia (AGA) is the most diagnosed hair loss dysfunction. Its physiopathology comprises a genetic predisposition affording an exacerbated response of the hair follicles cells to androgens aggravated by scalp inflammation and extrinsic factors. This paper presents a review of the mechanisms and extrinsic factors involved in the AGA physiopathology as well as its conventional and emerging treatments. The research focused on reports regarding AGA physiopathology and treatments published between January 2001 and July 2019 in medical and related journals. The most used medical treatments for AGA-minoxidil and finasteride-present non satisfactory results in some cases. Currently, the low-level laser therapy is recognized as a safe and effective treatment for AGA. Some minimally invasive techniques-mesotherapy, microneedling, carboxytherapy, and platelet-rich plasma-are also used to stimulate hair growth. Pharmaceutical substances with mechanisms differing from the anti-androgen activity are under current investigation and many of them have botanical origins; however, formulations with higher performance are required, and the hair follicles ability of being a drug and nanoparticle reservoir has been researched. The association of different strategies, that is, substances with synergic mechanisms and the use of advantageous technologies associated with lifestyle changes could improve the treatment outcomes.
추출된 의학 개체 (NER)
전체 NER 표 보기
| 유형 | 영어 표현 | 한국어 / 풀이 | UMLS CUI | 출처 | 등장 |
|---|---|---|---|---|---|
| 질환 | androgenetic alopecia
|
안드로겐성 탈모 | dict | 2 | |
| 질환 | androgenetic alopecia
|
안드로겐성 탈모 | dict | 2 | |
| 해부 | scalp
|
두피 | dict | 1 | |
| 해부 | scalp
|
두피 | dict | 1 | |
| 약물 | minoxidil
|
미녹시딜 | dict | 1 | |
| 약물 | finasteride
|
피나스테리드 | dict | 1 | |
| 약물 | minoxidil
|
미녹시딜 | dict | 1 | |
| 약물 | finasteride
|
피나스테리드 | dict | 1 |
🏷️ 키워드 / MeSH 📖 같은 키워드 OA만
인용 관계
그래프 OA 노드: 8/8 (100%)
· 참조 0편 · 후속 8편
이 논문을 인용한 후속 연구 20
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- Treatment of Androgenetic Alopecia: Current Guidance and Unmet Needs.
- Topical Treatment for Scarring and Non-Scarring Alopecia: An Overview of the Current Evidence.
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- Phytochemical Constitution, Anti-Inflammation, Anti-Androgen, and Hair Growth-Promoting Potential of…
- Female-pattern hair loss: therapeutic update.
- A Cross-sectional Study of Plasma Trace Elements and Vitamins Content in Androgenetic Alopecia in Me…
- Non-ablative Er:YAG laser is an effective tool in the treatment arsenal of androgenetic alopecia.
- Caizhixuan hair tonic regulates both apoptosis and the PI3K/Akt pathway to treat androgenetic alopec…
- Topical Delivery of Atraric Acid Derived from with Enhanced Skin Permeation and Hair Regrowth Activ…
- Androgenetic Alopecia Among Hospital Staff: A Study of Prevalence, Types and a Comparison with Gener…
- Trichoscopy of Androgenetic Alopecia: A Systematic Review.
- Androgenetic Alopecia in Men: An Update On Genetics.
- Scalp vascularization as a marker of topical minoxidil treatment efficacy in patients with androgene…
- Oxidative stress activates the transplanted adipose-derived stem cells to exert antioxidant effects …
- Male androgenetic alopecia.
- Topical dutasteride for androgenic alopecia: current state and prospects.
- Effectiveness and safety of the ablative fractional 2940-nm Er: YAG laser for the treatment of andro…
🏷️ 같은 키워드 · 무료전문 — 이 논문 MeSH/keyword 기반
📖 비슷한 OA 논문 — 같은 카테고리, 무료 전문 가능
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TL;DRAlopecia areata is difficult to manage medically, but recent advances in understanding the molecular mechanisms have revealed new treatments and the possibility of remission in the…
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Androgenetic alopecia: a review.
TL;DRA systematic review of the literature and candidate gene and genome-wide association studies have reported that single-nucleotide polymorphisms at different genomic loci are associ…
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Epidemiology and burden of alopecia areata: a systematic review.
TL;DRAA is the most prevalent autoimmune disorder and the second most prevalent hair loss disorder after androgenetic alopecia, and the lifetime risk in the global population is approxi…
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Two Phase 3 Trials of Baricitinib for Alopecia Areata.
TL;DRIn two phase 3 trials involving patients with severe alopecia areata, oral baricitinib was superior to placebo with respect to hair regrowth at 36 weeks.
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Treatment options for androgenetic alopecia: Efficacy, side effects, compliance, financial considerations, and ethics.
TL;DRAlthough a variety of medical, surgical, light‐based and nutraceutical treatment options are available to slow or reverse the progression of AGA, it can be challenging to select ap…