Alopecia areata and health-related quality of life: a systematic review and meta-analysis.
메타분석
4/5 보강
TL;DR
No systematic review has yet evaluated the available evidence on health‐related quality of life (HRQOL) in alopecia areata (AA).
PICO 자동 추출 (휴리스틱, conf 2/4)
유사 논문P · Population 대상 환자/모집단
환자: AA was 6·3 (95% confidence interval 5·6-7·1)
I · Intervention 중재 / 시술
추출되지 않음
C · Comparison 대조 / 비교
추출되지 않음
O · Outcome 결과 / 결론
Several generic and dermatology-specific HRQOL instruments have been used, but no validation studies have confirmed their applicability in AA. The newly developed AA-specific measures seem very promising; however, a more extensive assessment of validity and reliability is needed.
📑 코퍼스 인용 관계
· 인용됨 76
📑 인용한 논문 (6) ▾
- Illness Perception, Emotional Distress, and Obsessive-Compulsive Symptomatology in Patient… Behavioral sciences (Basel, Switzerland) · 2026
- Dermatologists' Perspectives and Real-World Assessment of Alopecia Areata Severity in Adul… Dermatology and therapy · 2026
- A systematic review and meta-synthesis of qualitative studies of alopecia: Managing identi… British journal of health psychology · 2026
- Stem cell-based therapies for alopecia areata: a narrative review. Stem cell research & therapy · 2026
- Responsiveness of the Dermatology Life Quality Index and the Colombian Validated Version o… Skin appendage disorders · 2025
- Cutaneous and Gut Dysbiosis in Alopecia Areata: A Review. JID innovations : skin science from molecules to population health · 2025
연도별 인용 (2016–2026) · 합계 230
OpenAlex 토픽 ·
Hair Growth and Disorders
Facial Rejuvenation and Surgery Techniques
Skin and Cellular Biology Research
Abstract 🌐 Abstract
[BACKGROUND] No systematic review has yet evaluated the available evidence on health-related quality of life (HRQOL) in alopecia areata (AA).
[OBJECTIVES] To conduct a systematic review and meta-analysis of HRQOL studies among patients diagnosed with AA.
[METHODS] A systematic search was performed for papers published between 1946 and 15 December 2014 in Medline, Embase, Web of Science, CINAHL, PsycINFO and the Cochrane Library. Random-effects meta-analyses were conducted to pool data.
[RESULTS] Twenty-one studies were included, representing a total of 2530 adult patients with AA. Of the 14 different HRQOL measures used in the studies, Dermatology Life Quality Index (DLQI; n = 8) and SF-36 (n = 7) were the most common. Three AA-specific HRQOL instruments were identified: Alopecia Areata Quality of Life Index, Alopecia Areata Quality of Life and Alopecia Areata Symptom Impact Scale. The mean pooled DLQI score of patients with AA was 6·3 (95% confidence interval 5·6-7·1). Comparing age- and sex-matched controls, the meta-analysis of SF-36 studies revealed significantly reduced HRQOL across the role-emotional, mental health and vitality domains (P < 0·001). Wearing a wig had a positive impact, while scalp involvement, anxiety and depression had a negative impact on HRQOL. Conflicting results were found regarding the association between HRQOL and age, sex, marital status and disease duration.
[CONCLUSIONS] Patients with AA experience significant impairment in HRQOL, especially in the area of mental health. Several generic and dermatology-specific HRQOL instruments have been used, but no validation studies have confirmed their applicability in AA. The newly developed AA-specific measures seem very promising; however, a more extensive assessment of validity and reliability is needed.
[OBJECTIVES] To conduct a systematic review and meta-analysis of HRQOL studies among patients diagnosed with AA.
[METHODS] A systematic search was performed for papers published between 1946 and 15 December 2014 in Medline, Embase, Web of Science, CINAHL, PsycINFO and the Cochrane Library. Random-effects meta-analyses were conducted to pool data.
[RESULTS] Twenty-one studies were included, representing a total of 2530 adult patients with AA. Of the 14 different HRQOL measures used in the studies, Dermatology Life Quality Index (DLQI; n = 8) and SF-36 (n = 7) were the most common. Three AA-specific HRQOL instruments were identified: Alopecia Areata Quality of Life Index, Alopecia Areata Quality of Life and Alopecia Areata Symptom Impact Scale. The mean pooled DLQI score of patients with AA was 6·3 (95% confidence interval 5·6-7·1). Comparing age- and sex-matched controls, the meta-analysis of SF-36 studies revealed significantly reduced HRQOL across the role-emotional, mental health and vitality domains (P < 0·001). Wearing a wig had a positive impact, while scalp involvement, anxiety and depression had a negative impact on HRQOL. Conflicting results were found regarding the association between HRQOL and age, sex, marital status and disease duration.
[CONCLUSIONS] Patients with AA experience significant impairment in HRQOL, especially in the area of mental health. Several generic and dermatology-specific HRQOL instruments have been used, but no validation studies have confirmed their applicability in AA. The newly developed AA-specific measures seem very promising; however, a more extensive assessment of validity and reliability is needed.
- 표본수 (n) 8
- 연구 설계 systematic review
No systematic review has yet evaluated the available evidence on health‐related quality of life (HRQOL) in alopecia areata (AA).
APA 7
Rencz, F., L, G., M, P., N, W., Baji, P., & Brodszky, V. (2016). Alopecia areata and health-related quality of life: A systematic review and meta-analysis.. The British journal of dermatology, 175(3), 561-71. https://doi.org/10.1111/bjd.14497
Vancouver
Rencz F, L G, M P, N W, Baji P, Brodszky V. Alopecia areata and health-related quality of life: a systematic review and meta-analysis. Brit. jour. derm.. 2016;175(3):561-71. doi:10.1111/bjd.14497
AMA 11
Rencz F, L G, M P, N W, Baji P, Brodszky V. Alopecia areata and health-related quality of life: a systematic review and meta-analysis. Brit. jour. derm.. 2016;175(3):561-71. doi:10.1111/bjd.14497
Chicago
Rencz, F., L, G., M, P., N, W., Baji, P., and Brodszky, V.. 2016. "Alopecia areata and health-related quality of life: a systematic review and meta-analysis." The British journal of dermatology 175 (3): 561-71. https://doi.org/10.1111/bjd.14497
MLA 9
Rencz, F., et al. "Alopecia areata and health-related quality of life: a systematic review and meta-analysis." The British journal of dermatology, vol. 175, no. 3, 2016, pp. 561-71. doi:10.1111/bjd.14497.
PMID
26914830 ↗
추출된 의학 개체 (NER)
전체 NER 표 보기
| 유형 | 영어 표현 | 한국어 / 풀이 | UMLS CUI | 출처 | 등장 |
|---|---|---|---|---|---|
| 질환 | alopecia areata
|
원형 탈모증 | dict | 5 | |
| 질환 | alopecia areata
|
원형 탈모증 | dict | 5 | |
| 질환 | alopecia areata
|
원형 탈모증 | dict | 5 | |
| 해부 | scalp
|
두피 | dict | 1 | |
| 해부 | scalp
|
두피 | dict | 1 | |
| 해부 | scalp
|
두피 | dict | 1 |
🏷️ 키워드 / MeSH 📖 같은 키워드 OA만
인용 관계
그래프 OA 노드: 8/8 (100%)
· 참조 0편 · 후속 8편
이 논문을 인용한 후속 연구 20
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- "'You lose your hair, what's the big deal?' I was so embarrassed, I was so self-conscious, I was so …
- Review of quality of life studies in women with alopecia.
- A Large Cross-Sectional Survey Study of the Prevalence of Alopecia Areata in the United States.
- Psychological Profile and Quality of Life of Patients with Alopecia Areata.
- Scalp biomarkers during dupilumab treatment support Th2 pathway pathogenicity in alopecia areata.
- Development of the Scalp Hair Assessment PRO™ measure for alopecia areata.
- Cumulative Life Course Impairment of Alopecia Areata.
- Application of Topical Immunotherapy in the Treatment of Alopecia Areata: A Review and Update.
- Health-Related Quality of Life in Patients With Frontal Fibrosing Alopecia.
- Treatments for alopecia areata: a network meta-analysis.
- Health-related quality of life in patients with alopecia areata: Results of a Japanese survey with n…
- Patient characteristics and disease burden of alopecia areata in the Danish Skin Cohort.
- Clinical and Genetic Aspects of Alopecia Areata: A Cutting Edge Review.
- Autoantigen Discovery in the Hair Loss Disorder, Alopecia Areata: Implication of Post-Translational …
- Patient and physician perspectives on alopecia areata: A real-world assessment of severity and burde…
- Dermatologist and Patient Perceptions of Treatment Success in Alopecia Areata and Evaluation of Clin…
- Characterizing the relationships between patient-reported outcomes and clinician assessments of alop…
같은 제1저자의 인용 많은 논문 (2)
🏷️ 같은 키워드 · 무료전문 — 이 논문 MeSH/keyword 기반
📖 비슷한 OA 논문 — 같은 카테고리, 무료 전문 가능
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Alopecia areata.
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Epidemiology and burden of alopecia areata: a systematic review.
TL;DRAA is the most prevalent autoimmune disorder and the second most prevalent hair loss disorder after androgenetic alopecia, and the lifetime risk in the global population is approxi…
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Two Phase 3 Trials of Baricitinib for Alopecia Areata.
TL;DRIn two phase 3 trials involving patients with severe alopecia areata, oral baricitinib was superior to placebo with respect to hair regrowth at 36 weeks.
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Treatment options for androgenetic alopecia: Efficacy, side effects, compliance, financial considerations, and ethics.
TL;DRAlthough a variety of medical, surgical, light‐based and nutraceutical treatment options are available to slow or reverse the progression of AGA, it can be challenging to select ap…
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Hair follicle immune privilege and its collapse in alopecia areata.
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