Persistent sexual side effects of finasteride for male pattern hair loss.
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TL;DR
The types and duration of sexual dysfunction and the changes in perceived sexual frequency and sexual dysfunction score between pre- and post-finasteride use are characterized.
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· 인용됨 70
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연도별 인용 (2012–2026) · 합계 278
OpenAlex 토픽 ·
Hair Growth and Disorders
Sexual function and dysfunction studies
Facial Rejuvenation and Surgery Techniques
Abstract 🌐 Abstract
[INTRODUCTION] Finasteride has been associated with reversible adverse sexual side effects in multiple randomized, controlled trials for the treatment of male pattern hair loss (MPHL). The Medicines and Healthcare Products Regulatory Agency of the United Kingdom and the Swedish Medical Products Agency have both updated their patient information leaflets to include a statement that "persistence of erectile dysfunction after discontinuation of treatment with Propecia has been reported in post-marketing use."
[AIM] We sought to characterize the types and duration of persistent sexual side effects in otherwise healthy men who took finasteride for MPHL.
[METHODS] We conducted standardized interviews with 71 otherwise healthy men aged 21-46 years who reported the new onset of sexual side effects associated with the temporal use of finasteride, in which the symptoms persisted for at least 3 months despite the discontinuation of finasteride.
[MAIN OUTCOME MEASURES] The types and duration of sexual dysfunction and the changes in perceived sexual frequency and sexual dysfunction score between pre- and post-finasteride use.
[RESULTS] Subjects reported new-onset persistent sexual dysfunction associated with the use of finasteride: 94% developed low libido, 92% developed erectile dysfunction, 92% developed decreased arousal, and 69% developed problems with orgasm. The mean number of sexual episodes per month dropped and the total sexual dysfunction score increased for before and after finasteride use according to the Arizona Sexual Experience Scale (P<0.0001 for both). The mean duration of finasteride use was 28 months and the mean duration of persistent sexual side effects was 40 months from the time of finasteride cessation to the interview date. Study limitations include a post hoc approach, selection bias, recall bias for before finasteride data, and no serum hormone levels.
[CONCLUSION] Physicians treating MPHL should discuss the potential risk of persistent sexual side effects associated with finasteride.
[AIM] We sought to characterize the types and duration of persistent sexual side effects in otherwise healthy men who took finasteride for MPHL.
[METHODS] We conducted standardized interviews with 71 otherwise healthy men aged 21-46 years who reported the new onset of sexual side effects associated with the temporal use of finasteride, in which the symptoms persisted for at least 3 months despite the discontinuation of finasteride.
[MAIN OUTCOME MEASURES] The types and duration of sexual dysfunction and the changes in perceived sexual frequency and sexual dysfunction score between pre- and post-finasteride use.
[RESULTS] Subjects reported new-onset persistent sexual dysfunction associated with the use of finasteride: 94% developed low libido, 92% developed erectile dysfunction, 92% developed decreased arousal, and 69% developed problems with orgasm. The mean number of sexual episodes per month dropped and the total sexual dysfunction score increased for before and after finasteride use according to the Arizona Sexual Experience Scale (P<0.0001 for both). The mean duration of finasteride use was 28 months and the mean duration of persistent sexual side effects was 40 months from the time of finasteride cessation to the interview date. Study limitations include a post hoc approach, selection bias, recall bias for before finasteride data, and no serum hormone levels.
[CONCLUSION] Physicians treating MPHL should discuss the potential risk of persistent sexual side effects associated with finasteride.
- p-value P<0.0001
The types and duration of sexual dysfunction and the changes in perceived sexual frequency and sexual dysfunction score between pre- and post-finasteride use are characterized.
APA 7
Irwig, M. S., & Kolukula, S. (2011). Persistent sexual side effects of finasteride for male pattern hair loss.. The journal of sexual medicine, 8(6), 1747-53. https://doi.org/10.1111/j.1743-6109.2011.02255.x
Vancouver
Irwig MS, Kolukula S. Persistent sexual side effects of finasteride for male pattern hair loss. jour. sexu. medi.. 2011;8(6):1747-53. doi:10.1111/j.1743-6109.2011.02255.x
AMA 11
Irwig MS, Kolukula S. Persistent sexual side effects of finasteride for male pattern hair loss. jour. sexu. medi.. 2011;8(6):1747-53. doi:10.1111/j.1743-6109.2011.02255.x
Chicago
Irwig, M. S., and Kolukula, S.. 2011. "Persistent sexual side effects of finasteride for male pattern hair loss." The journal of sexual medicine 8 (6): 1747-53. https://doi.org/10.1111/j.1743-6109.2011.02255.x
MLA 9
Irwig, M. S., and Kolukula S. "Persistent sexual side effects of finasteride for male pattern hair loss." The journal of sexual medicine, vol. 8, no. 6, 2011, pp. 1747-53. doi:10.1111/j.1743-6109.2011.02255.x.
PMID
21418145 ↗
🏷️ 키워드 / MeSH 📖 같은 키워드 OA만
인용 관계
그래프 OA 노드: 6/8 (75%)
· 참조 0편 · 후속 6편
이 논문을 인용한 후속 연구 20
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🏷️ 같은 키워드 · 무료전문 — 이 논문 MeSH/keyword 기반
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- 양성 전립선 비대증 남성에서 급성 요폐의 위험과 수술적 치료 필요성에 대한 finasteride의 효과. Finasteride Long-Term Efficacy and Safety Study Group.
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