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6건 · 최신순- Developing Botulinum Toxin Drugs: Unexpected Challenges.
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Iatrogenic botulism: a risk for botulinum toxin's medical use?
Botulinum toxin (BT) is infamous for its extreme toxicity. If it enters the bloodstream, it can cause botulism presenting with a typical pattern of motor and autonomic dysfunction. An international expert panel organised by IAB-Interdiscipl…
- Botulinum Toxin: Preclinical and Clinical Aspects.
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Immunogenicity Associated with Aesthetic Botulinumtoxin A: A Survey of Asia-Pacific Physicians' Experiences and Recommendations.
[BACKGROUND] Most botulinum toxin A (BoNT/A) products contain unnecessary bacterial components that increase the risk of developing neutralizing antibodies (nAbs). Reports of secondary nonresponse and treatment failures (STF) due to nAbs ha…
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The immunology of botulinum toxin therapy: A brief summary.
Like all proteins foreign to the human body, also botulinum toxin (BT) is antigenic and may stimulate an immune response with formation of antibodies (BT-AB). Affected patients may no longer respond to BT therapy and various degrees of BT-A…
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Neurotoxin Impurities: A Review of Threats to Efficacy.
Recently launched esthetic botulinum toxin serotype A (BoNT/A) products include Nabota/Jeuveau, Meditoxin/Neuronox, and Botulax, which contain nontoxic accessory proteins and excipients. Clinical evidence supporting these formulations, incl…