Alopecia areata: An appraisal of new treatment approaches and overview of current therapies.
4/5 보강
TL;DR
The evidence supporting new treatment methods, among them Janus kinase inhibitors, are described and an overview of conventional therapy is provided with new insights gleaned from recent studies.
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· 인용됨 90
📑 인용한 논문 (6) ▾
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연도별 인용 (2018–2026) · 합계 247
OpenAlex 토픽 ·
Hair Growth and Disorders
Autoimmune Bullous Skin Diseases
Dupuytren's Contracture and Treatments
Abstract 🌐 Abstract
Many therapies are available for the treatment of alopecia areata, including topical, systemic, and injectable modalities. However, these treatment methods produce variable clinical outcomes and there are no currently available treatments that induce and sustain remission. When making management decisions, clinicians must first stratify patients into pediatric versus adult populations. Disease severity should then be determined (limited vs extensive) before deciding the final course of therapy. The second article in this continuing medical education series describes the evidence supporting new treatment methods, among them Janus kinase inhibitors. We evaluate the evidence concerning the efficacy, side effects, and durability of these medications. An overview of conventional therapy is also provided with new insights gleaned from recent studies. Finally, future promising therapeutic options that have not yet been fully evaluated will also be presented.
The evidence supporting new treatment methods, among them Janus kinase inhibitors, are described and an overview of conventional therapy is provided with new insights gleaned from recent studies.
APA 7
Strazzulla, L. C., Wang, E. H. C., Avila, L., K, L. S., Brinster, N., Christiano, A. M., & Shapiro, J. (2018). Alopecia areata: An appraisal of new treatment approaches and overview of current therapies.. Journal of the American Academy of Dermatology, 78(1), 15-24. https://doi.org/10.1016/j.jaad.2017.04.1142
Vancouver
Strazzulla LC, Wang EHC, Avila L, K LS, Brinster N, Christiano AM, et al. Alopecia areata: An appraisal of new treatment approaches and overview of current therapies. Jour. Amer. Acad. Derm.. 2018;78(1):15-24. doi:10.1016/j.jaad.2017.04.1142
AMA 11
Strazzulla LC, Wang EHC, Avila L, K LS, Brinster N, Christiano AM, et al. Alopecia areata: An appraisal of new treatment approaches and overview of current therapies. Jour. Amer. Acad. Derm.. 2018;78(1):15-24. doi:10.1016/j.jaad.2017.04.1142
Chicago
Strazzulla, L. C., Wang, E. H. C., Avila, L., K, L. S., Brinster, N., Christiano, A. M., and Shapiro, J.. 2018. "Alopecia areata: An appraisal of new treatment approaches and overview of current therapies." Journal of the American Academy of Dermatology 78 (1): 15-24. https://doi.org/10.1016/j.jaad.2017.04.1142
MLA 9
Strazzulla, L. C., et al. "Alopecia areata: An appraisal of new treatment approaches and overview of current therapies." Journal of the American Academy of Dermatology, vol. 78, no. 1, 2018, pp. 15-24. doi:10.1016/j.jaad.2017.04.1142.
PMID
29241773 ↗
추출된 의학 개체 (NER)
전체 NER 표 보기
| 유형 | 영어 표현 | 한국어 / 풀이 | UMLS CUI | 출처 | 등장 |
|---|---|---|---|---|---|
| 질환 | alopecia areata
|
원형 탈모증 | dict | 2 | |
| 질환 | alopecia areata
|
원형 탈모증 | dict | 2 | |
| 질환 | alopecia areata
|
원형 탈모증 | dict | 2 |
🏷️ 키워드 / MeSH 📖 같은 키워드 OA만
- Administration
- Oral
- Topical
- Adrenal Cortex Hormones
- Alopecia Areata
- Dermatologic Agents
- Education
- Medical
- Continuing
- Female
- Humans
- Immunotherapy
- Injections
- Intralesional
- Male
- Methotrexate
- Minoxidil
- Quality of Life
- Risk Assessment
- Severity of Illness Index
- Treatment Outcome
- JAK inhibitors
- alopecia areata
- alopecia totalis
… 외 4개
인용 관계
그래프 OA 노드: 7/8 (88%)
· 참조 0편 · 후속 7편
이 논문을 인용한 후속 연구 20
- Alopecia Areata: an Update on Etiopathogenesis, Diagnosis, and Management.
- Minoxidil and its use in hair disorders: a review.
- Functional complexity of hair follicle stem cell niche and therapeutic targeting of niche dysfunctio…
- Hair Regrowth Outcomes of Contact Immunotherapy for Patients With Alopecia Areata: A Systematic Revi…
- JAK Inhibitors for Treatment of Alopecia Areata.
- Alopecia Areata Treatment Patterns, Healthcare Resource Utilization, and Comorbidities in the US Pop…
- Baricitinib for the Treatment of Alopecia Areata.
- Novel potential therapeutic targets of alopecia areata.
- Alopecia Areata: Burden of Disease, Approach to Treatment, and Current Unmet Needs.
- The current state of knowledge of the immune ecosystem in alopecia areata.
- Monotherapy for Alopecia Areata: A Systematic Review and Network Meta-Analysis.
- A phase 2a randomized vehicle-controlled multi-center study of the safety and efficacy of delgocitin…
- Prevalence, comorbidities, and treatment patterns of Japanese patients with alopecia areata: A descr…
- Application of Topical Immunotherapy in the Treatment of Alopecia Areata: A Review and Update.
- Treatments for alopecia areata: a network meta-analysis.
- Hair Follicle Melanocytes Initiate Autoimmunity in Alopecia Areata: a Trigger Point.
- Oral Tofacitinib and Systemic Corticosteroids, Alone or in Combination, in Patients With Moderate-to…
- Alopecia Areata: Pathogenesis, Diagnosis, and Therapies.
- Clinical and Genetic Aspects of Alopecia Areata: A Cutting Edge Review.
- Comparative Efficacy and Safety of Janus Kinase Inhibitors Used in Alopecia Areata: A Systematic Rev…
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🏷️ 같은 키워드 · 무료전문 — 이 논문 MeSH/keyword 기반
📖 비슷한 OA 논문 — 같은 카테고리, 무료 전문 가능
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Alopecia areata.
TL;DRAlopecia areata is difficult to manage medically, but recent advances in understanding the molecular mechanisms have revealed new treatments and the possibility of remission in the…
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Epidemiology and burden of alopecia areata: a systematic review.
TL;DRAA is the most prevalent autoimmune disorder and the second most prevalent hair loss disorder after androgenetic alopecia, and the lifetime risk in the global population is approxi…
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Two Phase 3 Trials of Baricitinib for Alopecia Areata.
TL;DRIn two phase 3 trials involving patients with severe alopecia areata, oral baricitinib was superior to placebo with respect to hair regrowth at 36 weeks.
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Treatment options for androgenetic alopecia: Efficacy, side effects, compliance, financial considerations, and ethics.
TL;DRAlthough a variety of medical, surgical, light‐based and nutraceutical treatment options are available to slow or reverse the progression of AGA, it can be challenging to select ap…
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Hair follicle immune privilege and its collapse in alopecia areata.
TL;DRA key goal for effective AA management is the re‐establishment of a functional HF IP, which will also provide superior protection from disease relapse, and may confer increased sus…