Androgens and androgen receptor action in skin and hair follicles.
4/5 보강
TL;DR
The molecular pathophysiology of type 2 5α-reductase, AR coactivators, the paracrine factors deregulated in dermal papillae and the crosstalk between AR and Wnt signaling are reviewed in order to shed some light on new promising treatments.
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· 인용됨 41
📑 인용한 논문 (6) ▾
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연도별 인용 (2018–2026) · 합계 207
OpenAlex 토픽 ·
Hair Growth and Disorders
Cancer and Skin Lesions
melanin and skin pigmentation
Abstract 🌐 Abstract
Beyond sexual functions, androgens exert their action in skin physiology and pathophysiology. Skin cells are able to synthesize most active androgens from gonadal or adrenal precursors and the enzymes involved in skin steroidogenesis are implicated both in normal or pathological processes. Even when the role of androgens and androgen receptor (AR) in skin pathologies has been studied for decades, their molecular mechanisms in skin disorders remain largely unknown. Here, we analyze recent studies of androgens and AR roles in several skin-related disorders, focusing in the current understanding of their molecular mechanisms in androgenetic alopecia (AGA). We review the molecular pathophysiology of type 2 5α-reductase, AR coactivators, the paracrine factors deregulated in dermal papillae (such as TGF-β, IGF 1, WNTs and DKK-1) and the crosstalk between AR and Wnt signaling in order to shed some light on new promising treatments.
The molecular pathophysiology of type 2 5α-reductase, AR coactivators, the paracrine factors deregulated in dermal papillae and the crosstalk between AR and Wnt signaling are reviewed in order to shed
APA 7
Ceruti, J. M., GJ, L., & ME, B. (2018). Androgens and androgen receptor action in skin and hair follicles.. Molecular and cellular endocrinology, 465, 122-133. https://doi.org/10.1016/j.mce.2017.09.009
Vancouver
Ceruti JM, GJ L, ME B. Androgens and androgen receptor action in skin and hair follicles. Mole. cell. endo.. 2018;465:122-133. doi:10.1016/j.mce.2017.09.009
AMA 11
Ceruti JM, GJ L, ME B. Androgens and androgen receptor action in skin and hair follicles. Mole. cell. endo.. 2018;465:122-133. doi:10.1016/j.mce.2017.09.009
Chicago
Ceruti, J. M., GJ, L., and ME, B.. 2018. "Androgens and androgen receptor action in skin and hair follicles." Molecular and cellular endocrinology 465: 122-133. https://doi.org/10.1016/j.mce.2017.09.009
MLA 9
Ceruti, J. M., et al. "Androgens and androgen receptor action in skin and hair follicles." Molecular and cellular endocrinology, vol. 465, 2018, pp. 122-133. doi:10.1016/j.mce.2017.09.009.
PMID
28912032 ↗
추출된 의학 개체 (NER)
전체 NER 표 보기
| 유형 | 영어 표현 | 한국어 / 풀이 | UMLS CUI | 출처 | 등장 |
|---|---|---|---|---|---|
| 질환 | androgenetic alopecia
|
안드로겐성 탈모 | dict | 1 | |
| 질환 | androgenetic alopecia
|
안드로겐성 탈모 | dict | 1 | |
| 질환 | androgenetic alopecia
|
안드로겐성 탈모 | dict | 1 |
🏷️ 키워드 / MeSH 📖 같은 키워드 OA만
인용 관계
그래프 OA 노드: 8/8 (100%)
· 참조 0편 · 후속 8편
이 논문을 인용한 후속 연구 20
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같은 제1저자의 인용 많은 논문 (1)
🏷️ 같은 키워드 · 무료전문 — 이 논문 MeSH/keyword 기반
📖 비슷한 OA 논문 — 같은 카테고리, 무료 전문 가능
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