insight
✂️ 성형 🏥 중증 탈모 한방 반려 게놈 🌐 전체
← 뒤로

Long-term renewal of hair follicles from clonogenic multipotent stem cells.

🦱 탈모
4/5 보강
Proceedings of the National Academy of Sciences of the United States of America 📖 저널 OA 99.1% 2021: 31/31 OA 2022: 37/37 OA 2023: 68/68 OA 2024: 106/106 OA 2025: 306/306 OA 2026: 260/269 OA 2021~2026 2005 Vol.102(41) p. 14677-82 피인용 16회 참고 42건 cited 328 RCR 4.30 Hair Growth and Disorders
TL;DR It is demonstrated that clonogenicity is an intrinsic property of the adult stem cells of the hair follicle, and that there are many more stem cells in whisker follicles than could be anticipated from label-retaining experiments.
Retraction 확인
출처
PubMed DOI PMC OpenAlex Semantic 마지막 보강 2026-05-10
📑 코퍼스 인용 관계 · 인용됨 16 · 인용함 42
→ 이 논문이 인용한 논문 (4) ▾
📑 인용한 논문 (6) ▾
연도별 인용 (2012–2026) · 합계 140
OpenAlex 토픽 · Hair Growth and Disorders Skin and Cellular Biology Research Wound Healing and Treatments

Claudinot S, Nicolas M, Oshima H, Rochat A, Barrandon Y

📖 무료 전문 🟢 PMC 전문 PMC1253596 🔓 OA PDF oa
PubMed ↗ DOI ↗ BibTeX ↓ RIS ↓

Abstract

Adult stem cells are essential for tissue renewal, regeneration, and repair, and their expansion in culture is of paramount importance for regenerative medicine. Using the whisker follicle of the rat as a model system, we demonstrate that (i) clonogenicity is an intrinsic property of the adult stem cells of the hair follicle; (ii) after cultivation for >140 doublings, these stem cells, transplanted to the dermo-epidermal junction of newborn mouse skin, form part or all of the developing follicles; (iii) the stem cells incorporated into follicles are multipotent, because they generate all of the lineages of the hair follicle and sebaceous gland; (iv) thousands of hair follicles can be generated from the progeny of a single cultivated stem cell; (v) cultured stem cells express the self-renewal genes Bmi1 and Zfp145;(vi) several stem cells participate in the formation of a single hair bulb; and (vii) there are many more stem cells in whisker follicles than could be anticipated from label-retaining experiments.
📝 환자 설명용 한 줄

It is demonstrated that clonogenicity is an intrinsic property of the adult stem cells of the hair follicle, and that there are many more stem cells in whisker follicles than could be anticipated from

이 논문을 인용하기

↓ .bib ↓ .ris
APA 7 Claudinot, S., Nicolas, M., Oshima, H., Rochat, A., & Barrandon, Y. (2005). Long-term renewal of hair follicles from clonogenic multipotent stem cells.. Proceedings of the National Academy of Sciences of the United States of America, 102(41), 14677-82. https://doi.org/10.1073/pnas.0507250102
Vancouver Claudinot S, Nicolas M, Oshima H, Rochat A, Barrandon Y. Long-term renewal of hair follicles from clonogenic multipotent stem cells. Proc. Nati. Acad. Scie. Unit. Stat. Amer.. 2005;102(41):14677-82. doi:10.1073/pnas.0507250102
AMA 11 Claudinot S, Nicolas M, Oshima H, Rochat A, Barrandon Y. Long-term renewal of hair follicles from clonogenic multipotent stem cells. Proc. Nati. Acad. Scie. Unit. Stat. Amer.. 2005;102(41):14677-82. doi:10.1073/pnas.0507250102
Chicago Claudinot, S., Nicolas, M., Oshima, H., Rochat, A., and Barrandon, Y.. 2005. "Long-term renewal of hair follicles from clonogenic multipotent stem cells." Proceedings of the National Academy of Sciences of the United States of America 102 (41): 14677-82. https://doi.org/10.1073/pnas.0507250102
MLA 9 Claudinot, S., et al. "Long-term renewal of hair follicles from clonogenic multipotent stem cells." Proceedings of the National Academy of Sciences of the United States of America, vol. 102, no. 41, 2005, pp. 14677-82. doi:10.1073/pnas.0507250102.
PMID 16203973 ↗
DOI 10.1073/pnas.0507250102

🏷️ 키워드 / MeSH 📖 같은 키워드 OA만

인용 관계

그래프 OA 노드: 8/12 (67%) · 참조 2편 · 후속 6편

이 논문이 참조한 문헌 34

외부 PMID 30건 (DB 미수집)

이 논문을 인용한 후속 연구 16

같은 제1저자의 인용 많은 논문 (1)

🏷️ 같은 키워드 · 무료전문 — 이 논문 MeSH/keyword 기반

🟢 PMC 전문 열기