Alopecia areata: a review on diagnosis, immunological etiopathogenesis and treatment options.
4/5 보강
TL;DR
Research into immunology and genetics, more particularly in the field of dendritic cells (DC), is recommended for AA as there is evidence of the possible role of DC in the treatment of other autoimmune diseases such as multiple Sclerosis and cancer.
📑 코퍼스 인용 관계
· 인용됨 58 · 인용함 144
→ 이 논문이 인용한 논문 (6) ▾
- 'The psychosocial burden of alopecia areata and androgenetica': a cross-sectional multicen… Journal of the European Academy of Dermatology and Venereology : JEADV · 2020
- Serum level of IL-4 predicts response to topical immunotherapy with diphenylcyclopropenone… Experimental dermatology · 2020
- Alopecia totalis and universalis long-term outcomes: a review. Journal of the European Academy of Dermatology and Venereology : JEADV · 2020
- Development of the Scalp Hair Assessment PRO™ measure for alopecia areata. The British journal of dermatology · 2020
- Serum Vitamin D Levels and Alopecia Areata- A Hospital Based Case-Control Study from North… International journal of trichology · 2019
- A randomized placebo-controlled single-center pilot study of the safety and efficacy of ap… Archives of dermatological research · 2019
📑 인용한 논문 (6) ▾
- Effectiveness of Baricitinib on Nail Alopecia Areata: A 48-Week Single-Center Retrospectiv… Clinical drug investigation · 2026
- Comparative investigation of immune-related biomarkers related to alopecia areata subtypes… Archives of medical science : AMS · 2025
- Mechanism of PPARα agonist in alopecia areata. American journal of translational research · 2025
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- Serum-Based Assessment of Alopecia Areata Response to Treatment Using ATR-FTIR Spectroscop… Diagnostics (Basel, Switzerland) · 2025
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연도별 인용 (2021–2026) · 합계 153
OpenAlex 토픽 ·
Hair Growth and Disorders
Dermatology and Skin Diseases
Autoimmune Bullous Skin Diseases
Abstract 🌐 Abstract
Patients suffering from alopecia areata (AA) can lose hair in focal regions, the complete scalp, including eyelashes and eyebrows, or even the entire body. The exact pathology is not yet known, but the most described theory is a collapse of the immune privilege system, which can be found in some specific regions of the body. Different treatment options, local and systemic, are available, but none of them have been proven to be effective in the long term as well for every treatment there should be considered for the possible side effects. In many cases, treated or non-treated, relapse often occurs. The prognosis is uncertain and is negatively influenced by the subtypes alopecia totalis and alopecia universalis and characteristics such as associated nail lesions, hair loss for more than 10 years and a positive familial history. The unpredictable course of the disease also makes it a mental struggle and AA patients are more often associated with depression and anxiety compared to the healthy population. Research into immunology and genetics, more particularly in the field of dendritic cells (DC), is recommended for AA as there is evidence of the possible role of DC in the treatment of other autoimmune diseases such as multiple Sclerosis and cancer. Promising therapies for the future treatment of AA are JAK-STAT inhibitors and PRP.
Research into immunology and genetics, more particularly in the field of dendritic cells (DC), is recommended for AA as there is evidence of the possible role of DC in the treatment of other autoimmun
APA 7
Sterkens, A., Lambert, J., & Bervoets, A. (2021). Alopecia areata: A review on diagnosis, immunological etiopathogenesis and treatment options.. Clinical and experimental medicine, 21(2), 215-230. https://doi.org/10.1007/s10238-020-00673-w
Vancouver
Sterkens A, Lambert J, Bervoets A. Alopecia areata: a review on diagnosis, immunological etiopathogenesis and treatment options. Clin. expe. medi.. 2021;21(2):215-230. doi:10.1007/s10238-020-00673-w
AMA 11
Sterkens A, Lambert J, Bervoets A. Alopecia areata: a review on diagnosis, immunological etiopathogenesis and treatment options. Clin. expe. medi.. 2021;21(2):215-230. doi:10.1007/s10238-020-00673-w
Chicago
Sterkens, A., Lambert, J., and Bervoets, A.. 2021. "Alopecia areata: a review on diagnosis, immunological etiopathogenesis and treatment options." Clinical and experimental medicine 21 (2): 215-230. https://doi.org/10.1007/s10238-020-00673-w
MLA 9
Sterkens, A., et al. "Alopecia areata: a review on diagnosis, immunological etiopathogenesis and treatment options." Clinical and experimental medicine, vol. 21, no. 2, 2021, pp. 215-230. doi:10.1007/s10238-020-00673-w.
PMID
33386567 ↗
추출된 의학 개체 (NER)
전체 NER 표 보기
| 유형 | 영어 표현 | 한국어 / 풀이 | UMLS CUI | 출처 | 등장 |
|---|---|---|---|---|---|
| 질환 | alopecia areata
|
원형 탈모증 | dict | 2 | |
| 질환 | alopecia areata
|
원형 탈모증 | dict | 2 | |
| 해부 | scalp
|
두피 | dict | 1 | |
| 해부 | scalp
|
두피 | dict | 1 |
🏷️ 키워드 / MeSH 📖 같은 키워드 OA만
인용 관계
그래프 OA 노드: 12/16 (75%)
· 참조 5편 · 후속 7편
이 논문이 참조한 문헌 50
- Alopecia areata.
- Alopecia areata is driven by cytotoxic T lymphocytes and is reversed by JAK inhibition.
- Genome-wide association study in alopecia areata implicates both innate and adaptive immunity.
- Epidemiology and burden of alopecia areata: a systematic review.
- Minoxidil: mechanisms of action on hair growth.
- The effectiveness of treatments for androgenetic alopecia: A systematic review and meta-analysis.
- Safety and efficacy of the JAK inhibitor tofacitinib citrate in patients with alopecia areata.
- Tofacitinib for the treatment of severe alopecia areata and variants: A study of 90 patients.
- The Effect of Platelet-Rich Plasma in Hair Regrowth: A Randomized Placebo-Controlled Trial.
- Alopecia areata profiling shows TH1, TH2, and IL-23 cytokine activation without parallel TH17/TH22 s…
- A randomized, placebo-controlled trial of 5% and 2% topical minoxidil solutions in the treatment of …
- Tofacitinib for the treatment of alopecia areata and variants in adolescents.
- The Role of Micronutrients in Alopecia Areata: A Review.
- Alopecia areata: Clinical presentation, diagnosis, and unusual cases.
- Platelet-rich plasma in androgenic alopecia: myth or an effective tool.
- Trichoscopy of alopecia areata: An update.
- Alopecia areata: Animal models illuminate autoimmune pathogenesis and novel immunotherapeutic strate…
- Biomarkers of alopecia areata disease activity and response to corticosteroid treatment.
- 'The psychosocial burden of alopecia areata and androgenetica': a cross-sectional multicentre study …
- Nail changes in alopecia areata: an update and review.
외부 PMID 30건 (DB 미수집)
- PMID 10504438 ↗
- PMID 11148480 ↗
- PMID 12084906 ↗
- PMID 12444333 ↗
- PMID 12542742 ↗
- PMID 12833016 ↗
- PMID 13610145 ↗
- PMID 14676070 ↗
- PMID 15337988 ↗
- PMID 15889264 ↗
- PMID 15918897 ↗
- PMID 16164707 ↗
- PMID 16416652 ↗
- PMID 16427504 ↗
- PMID 16550198 ↗
- PMID 16551260 ↗
- PMID 16650161 ↗
- PMID 16675965 ↗
- PMID 17010743 ↗
- PMID 17911990 ↗
- PMID 18248767 ↗
- PMID 19931651 ↗
- PMID 20193016 ↗
- PMID 21060941 ↗
- PMID 21679864 ↗
- PMID 21995572 ↗
- PMID 22525048 ↗
- PMID 22790179 ↗
- PMID 22795876 ↗
- PMID 22923897 ↗
이 논문을 인용한 후속 연구 20
- Alopecia Areata: Current Treatments and New Directions.
- Janus Kinase Inhibitors for Alopecia Areata: A Systematic Review and Meta-Analysis.
- Status of research on the development and regeneration of hair follicles.
- The Roles of Exosomes in Regulating Hair Follicle Growth.
- Clinical and Genetic Aspects of Alopecia Areata: A Cutting Edge Review.
- Real-Life Effectiveness and Tolerance of Baricitinib for the Treatment of Severe Alopecia Areata wit…
- The Role of Minoxidil in Treatment of Alopecia Areata: A Systematic Review and Meta-Analysis.
- Gut microbiome, metabolome and alopecia areata.
- Classification Framework for Healthy Hairs and Alopecia Areata: A Machine Learning (ML) Approach.
- Alopecia Areata: Understanding the Pathophysiology and Advancements in Treatment Modalities.
- An Update on Alopecia and its Association With Thyroid Autoimmune Diseases.
- Fractional carbon dioxide laser alone and as an assisted drug delivery for treatment of alopecia are…
- Oxidative stress and alopecia areata.
- Significant efficacy of tofacitinib from China in the treatment of alopecia areata: a case report.
- A Three-Step Diagnostic Algorithm for Alopecia: Pattern Analysis in Trichoscopy.
- Impact of SDF-1 and AMD3100 on Hair Follicle Dynamics in a Chronic Stress Model.
- Co-regulatory mechanisms and potential markers of oxidative stress-related genes in vitiligo and alo…
- Growth Factors and Microneedling in Alopecia Areata: A Narrative Review.
- A comparative study of fractional CO laser with topical triamcinolone acetonide versus intralesional…
- Efficacy and safety of baricitinib in patients with alopecia areata: evidence to date.
🏷️ 같은 키워드 · 무료전문 — 이 논문 MeSH/keyword 기반
📖 비슷한 OA 논문 — 같은 카테고리, 무료 전문 가능
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Alopecia areata.
TL;DRAlopecia areata is difficult to manage medically, but recent advances in understanding the molecular mechanisms have revealed new treatments and the possibility of remission in the…
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Epidemiology and burden of alopecia areata: a systematic review.
TL;DRAA is the most prevalent autoimmune disorder and the second most prevalent hair loss disorder after androgenetic alopecia, and the lifetime risk in the global population is approxi…
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Two Phase 3 Trials of Baricitinib for Alopecia Areata.
TL;DRIn two phase 3 trials involving patients with severe alopecia areata, oral baricitinib was superior to placebo with respect to hair regrowth at 36 weeks.
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Treatment options for androgenetic alopecia: Efficacy, side effects, compliance, financial considerations, and ethics.
TL;DRAlthough a variety of medical, surgical, light‐based and nutraceutical treatment options are available to slow or reverse the progression of AGA, it can be challenging to select ap…
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Alopecia areata: A multifactorial autoimmune condition.
TL;DRVarious genetic and environmental factors that cause autoimmunity are discussed and the immune mechanisms that lead to hair loss in alopecia areata patients are described.